259133-72-7

Upstream product

• 1005-56-7 phenylcarbonochloridothioate 
• 259133-71-6 (2R,6R)-2-hydroxymethyl-6-propyl-N-Boc-piperidine 
• 675-20-7 piperidin-2-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 150521-32-7 (S)-1-N-Boc-piperidine-2-al 
• 85275-45-2 N-tert-butoxycarbonyl-3-piperidinol 
• 131667-57-7 tert-butyl 1,2,3,4-tetrahydro-1-pyridinecarboxylate 
• 86953-81-3 tert-butyl 2-hydroxypiperidine-1-carboxylate 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 26250-84-0 (S)-(-)-1-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid 
• 134441-93-3 tert-butyl (2S)-2-(hydroxymethyl)piperidine-1-carboxylate 
• 147974-34-3 2-propyl-piperidine-1-carboxylic acid tert-butyl ester 
• 146337-23-7 tert-butyl 3-methoxypiperidine-1-carboxylate 
• 259133-70-5 tert-butyl (2R,6R)-2-formyl-6-propylpiperidine-1-carboxylate 

Relevant academic research and scientific papers

Enantioselective syntheses of 2-alkyl- and 2,6-dialkylpiperidine alkaloids: preparations of the hydrochlorides of (-)-coniine, (-)-solenopsin A, and (-)-dihydropinidine.

[reaction: see text] Sequences of lithiation-substitution, enantioselective hydrogenation, and diastereoselective lithiation-substitution provide efficient highly enantioselective syntheses of 2-substituted and cis and trans 2,6-disubstituted piperidines.