26218-50-8

Basic information

• Product Name: 2-Propynamide, N,N-dimethyl-3-phenyl-
• CAS NO: 26218-50-8
• Molecular Formula: C11H11NO
• Molecular Weight: 173.214
• Mol File: 26218-50-8.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 2-Propynamide, N,N-dimethyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynamide, N,N-dimethyl-3-phenyl-(26218-50-8)
• EPA Substance Registry System: 2-Propynamide, N,N-dimethyl-3-phenyl-(26218-50-8)

Safety Data

• Hazardous Substances Data: 26218-50-8(Hazardous Substances Data)

Upstream product

• 7299-58-3 phenylpropiolyl chloride 
• 124-40-3 dimethyl amine 
• 1004-22-4 (phenylethynyl)sodium 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 40233-44-1 (E)-3-Chloro-N,N-dimethyl-3-phenyl-acrylamide 
• 536-74-3 phenylacetylene 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 479486-96-9 N,N-dimethyl (trimethylsilyl)methanamide 
• 2579-22-8 Phenylpropargyl aldehyde 
• 68-12-2 N,N-dimethyl-formamide 
• 7342-02-1 3-phenylpropynoic acid phenylamide 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 28995-82-6 ((Z)-1-Iodo-2-methanesulfonyl-vinyl)-benzene 

Downstream Products

• 131214-20-5 (2Z)-N,N-dimethyl-3-phenyl-2-propenamide 
• 1360896-26-9 (E)-N,N-dimethyl-3-phenyl-2-(triethoxysilyl)acrylamide 
• 1279110-68-7 C₁₈H₁₇NO₃ 
• 1279110-67-6 C₁₈H₁₇NO₃ 
• 922522-23-4 [TaCl₃(PhCCCONMe₂)(pyridine)2] 
• 129741-70-4 (E)-(trimethylstannyl)(CONMe₂)CC(Ph)(PPh₂) 
• 129741-69-1 (trimethylstannyl)(CONMe₂)CC(Ph)(PPh₂) 

Relevant articles and documents

Manganese Catalyzed Enantioselective Epoxidation of α,β-Unsaturated Amides with H2O2

Herewith, we report the enantioselective epoxidation of electron-deficient cis- and trans-α,β-unsaturated amides with the environmentally benign oxidant H2O2. The catalysts - manganese complexes with bis-amino-bis-pyridine and structurally related ligands - exhibit reasonably high efficiency (up to 100 TON) and excellent chemo- and enantioselectivity (up to 100% and 99% ee, respectively). Crucially, the cis-enamides epoxidation enantioselectivity and yield are dramatically enhanced by the presence of NH-moiety, which effect can be explained by the hydrogen bonding interaction between the cis-enamide substrate and the manganese based oxygen transferring species. (Figure presented.).

CuCl2-catalyzed highly stereoselective and chemoselective reduction of alkynyl amides into α,β-unsaturated amides using silanes as hydrogen donors

A CuH-catalyzed Z-selective partial reduction of alkynyl amides to afford α,β-unsaturated amides using silane as the hydrogen donor is developed. This reaction is carried out under mild conditions and able to accommodate a broad scope of alkynyl amides in

Water as a Hydrogenating Agent: Stereodivergent Pd-Catalyzed Semihydrogenation of Alkynes

Palladium-catalyzed transfer semihydrogenation of alkynes using H2O as the hydrogen source and Mn as the reducing reagent is developed, affording cis- and trans-alkenes selectively under mild conditions. In addition, this method provides an efficient way to access various cis-1,2-dideuterioalkenes and trans-1,2-dideuterioalkenes by using D2O instead of H2O.