26287-73-0

Basic information

• Product Name: 1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL
• Synonyms: 1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL
• CAS NO: 26287-73-0
• Molecular Formula: C₃₀H₂₄N₂O₉
• Molecular Weight: 556.525
• Mol File: 26287-73-0.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• PKA: 9.39±0.10(Predicted)
• CAS DataBase Reference: 1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL(26287-73-0)
• EPA Substance Registry System: 1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL(26287-73-0)

Safety Data

• Hazardous Substances Data: 26287-73-0(Hazardous Substances Data)

Usage

General Description

1-(2'', 3'', 5''-tri-O-benzoyl-β-L-ribofuranosyl)uracil is a chemical compound that consists of a uracil molecule linked to a ribose sugar with three benzoyl groups attached to the ribofuranosyl moiety. 1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL is a modified nucleoside molecule that is commonly used in biochemical and medicinal research as a substrate for nucleic acid studies. The benzoyl groups serve to protect the ribose sugar from chemical reactions, allowing for precise modification and manipulation of the nucleoside for specific research purposes. In addition, the compound's modified structure also affects its biochemical and pharmacological properties, making it a valuable tool for studying nucleic acid functions and potential drug development.

Upstream product

• 3080-30-6 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose 
• 66-22-8 uracil 
• 31615-98-2 1-(3,5-Di-O-benzoyl-β-L-arabinofuranosyl)uracil 
• 171866-28-7 1-O-methyl-2,3,5-tri-O-benzoyl-L-ribofuranose 
• 31615-96-0 3',5'-di-O-benzoyl-2,2'-anhydro-L-uridine 
• 31501-46-9 (2S,3S,3aR,9aS)-3-hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2,3’:4,5]oxazolo[3,2-a]pyrimidin-6-one 
• 35939-60-7 2-amino-β-L-arabinofurano[1',2':4,5]oxazoline 
• 532-32-1 sodium benzoate 
• 259856-99-0 1-(β-L-arabinofuranosyl-2-O-methanesulfonyl-3,5-di-O-benzoyl)uracil 
• 98-88-4 benzoyl chloride 
• 58-96-8 1-(β-L-arabinofuranosyl)-uracil 
• 120019-54-7 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-arabinofuranoside 
• 613-90-1 benzoyl cyanide 

Downstream Products

• 1382804-43-4 C₃₄H₂₅ClN₂O₉S 
• 1382804-45-6 C₃₄H₂₅BrN₂O₉S 
• 1382804-47-8 C₃₄H₂₅IN₂O₉S 
• 1382804-54-7 C₃₀H₂₄IN₃O₈ 
• 1382804-56-9 C₃₄H₂₇N₃O₈S 
• 1382804-58-1 C₃₄H₂₆ClN₃O₈S 
• 1382804-60-5 C₃₄H₂₆BrN₃O₈S 
• 1382804-62-7 C₃₄H₂₆IN₃O₈S 
• 1382804-38-7 C₃₀H₂₃ClN₂O₉ 
• 1382804-40-1 C₃₀H₂₃BrN₂O₉ 
• 552827-64-2 C₃₀H₂₃IN₂O₉ 
• 1382804-41-2 C₃₄H₂₆N₂O₉S 
• 77210-26-5 1-(3'-O-benzyl-β-L-ribofuranosyl)-5-fluorouracil 
• 58-97-9 L-uridine 5'-monophosphate 

Relevant articles and documents

MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF

The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.

An economical synthesis of D- and L-pyrimidine arabinoand ribonucleosides

The one-step synthesis of several β-D/L-arabino- and ribonucleosides was performed in good yields under reflux or microwave-assisted fusion method. A comparison of the two methods showed that better yields were obtained using the reflux conditions. Copyright Taylor and Francis Group, LLC.

L-Ribonucleosides from L-xylose

L-Xylose was converted into a L-ribose derivative via an oxidation/reduction procedure. The L-ribosyl donor was submitted to a glycosidation reaction according to Vorbruggen's conditions to give L- ribonucleosides (L-uridine, L-cytidine, L-adenosine and L-guanosine) in high yield.