26340-49-8Relevant articles and documents
Generation and reactions of 2,3-dilithio-N-methylindole. Synthesis of 2,3-disubstituted indoles
Liu, Yanbing,Gribble, Gordon W.
, p. 2949 - 2951 (2001)
Generation of 2,3-dilithio-N-methylindole (7) from 2,3-diiodo-N-methylindole (6) and subsequent reaction with various electrophiles (NH4Cl, DMF, ClCO2Me, CO2, phthalic anhydride) affords the corresponding 2,3-disubstituted indoles in good to excellent yields (41-99%).
Aerobic Oxidative C-H Azolation of Indoles and One-Pot Synthesis of Azolyl Thioindoles by Flavin-Iodine-Coupled Organocatalysis
Tanimoto, Kazumasa,Okai, Hayaki,Oka, Marina,Ohkado, Ryoma,Iida, Hiroki
, p. 2084 - 2088 (2021/04/05)
The aerobic oxidative cross-coupling of indoles with azoles driven by flavin-iodine-coupled organocatalysis has been developed for the green synthesis of 2-(azol-1-yl)indoles. The coupled organocatalytic system enabled the one-pot three-component synthesis of 2-azolyl-3-thioindoles from indoles, azoles, and thiols in an atom-economical manner by utilizing molecular oxygen as the only sacrificial reagent.
Heat Versus Basic Conditions: Intramolecular Dehydro-Diels-Alder Reaction of 1-Indolyl-1,6-heptadiynes for the Selective Synthesis of Substituted Carbazoles
Kudoh, Takayuki,Fujisawa, Syo,Kitamura, Megumi,Sakakura, Akira
, p. 2189 - 2193 (2017/09/26)
The intramolecular dehydro-Diels-Alder reaction of 1-indolyl-1,6-heptadiynes proceeds smoothly under rather mild heating conditions to give substituted carbazoles in moderate to good yields. The reaction of 7-aryl-1-indolyl-1,6-heptadiynes under heating gives the corresponding carbazoles chemoselectively in high yields, whereas the reaction under basic conditions gives naphthalenes as major products.
Sterically controlled iodination of arenes via iridium-catalyzed C-H borylation
Partridge, Benjamin M.,Hartwig, John F.
, p. 140 - 143 (2013/03/28)
A mild method to prepare aryl and heteroaryl iodides by sequential C-H borylation and iodination is reported. The regioselectivity of this process is controlled by steric effects on the C-H borylation step and is complementary to existing methods to form aryl iodides. The iodination of boronic esters has potential for the synthesis of radiolabeled aryl iodides, as demonstrated by the concise synthesis of a potential tracer for SPECT imaging.