2657-24-1Relevant academic research and scientific papers
β-phenyl quenching of triplet excited ketones: How critical is the geometry for deactivation?
Samanta, Subhas,Mishra, Brijesh Kumar,Pace, Tamara C. S.,Sathyamurthy, Narayanasami,Bohne, Cornelia,Moorthy, Jarugu Narasimha
, p. 4453 - 4459 (2006)
The phenomenon of β-phenyl quenching has been examined by laser-flash photolysis in a series of α- and/or β-substituted ketones 4-8 with similar excited-state characteristics. It is found that α-substitution markedly increases the triplet lifetimes in con
Arylboronic Acid Catalyzed Dehydrative Mono-/Dialkylation Reactions of β-Ketoacids and Alcohols
Feng, Juhua,Hu, Haipeng,Ni, Hailiang,Qiu, Yuqian,Wang, Cuilin,Wang, Guangtu,Wang, Hanguang,Wang, Wei,Wu, Xin,Yue, Guizhou,Zou, Ping
supporting information, p. 832 - 836 (2022/02/05)
The dehydrative mono-/dialkylation reactions of alcohols and β-ketoacids were realized under arylboronic acid catalysis, furnishing a series of β-aryl ketones and β-ketoesters in yields of 15–99%, with CO2 and H2O being the byproduct
Microwave-Assisted Condensation of Benzylic Alcohols and Alkynes Promoted by Zinc Halides: Concise Access to Alkenyl Halides
Goel, Komal,Nandi, Poulomi,Satyanarayana, Gedu,Sreenivasulu, Chinnabattigalla
supporting information, p. 4851 - 4860 (2021/11/17)
A simple Lewis acid-mediated route for the synthesis of alkenyl halides are described under microwave-assisted conditions. The reaction proceeds through the condensation between secondary alcohols and terminal acetylenes and regioselective hydrohalogenati
An Atom-Economical Route to Substituted β-Arylethyl Ketones: Phosphomolybdic Acid-Catalyzed Carbohydroxylation of Terminal Alkynes in Organic Carbonate
Yang, Guo-Ping,Zhang, Nan,Ma, Nuan-Nuan,Yu, Bing,Hu, Chang-Wen
, p. 926 - 932 (2017/03/27)
A highly efficient and atom-economical route for the synthesis of substituted β-arylethyl ketones was developed by using cheap phosphomolybdic acid (H3PMo12O40) as catalyst and non-volatile propylene carbonate (PC) as green solvent via the carbohydroxylation of terminal alkynes with benzylic alcohols under mild conditions. Various functional groups on the benzylic alcohols and terminal alkynes were tolerated, giving the corresponding substituted β-arylethyl ketones as products in good to excellent yields (up to 95%). It is worth noting that a turnover number (TON) of up to 520 was achieved in the protocol. The mechanism investigation showed that PC might stabilize the heteropoly anion and the carbocation intermediate thus facilitating the carbohydroxylation reaction. (Figure presented.).
Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones
Zhong, Shanshan,Lu, Yu,Zhang, Yan,Liu, Yunyun,Wan, Jie-Ping
supporting information, p. 6270 - 6273 (2016/07/11)
The syntheses of β,β-diaryl aryl propiophenones have been realized via palladium-catalyzed domino reactions of dimethyl amino functionalized enaminones and aryl boronic acids. This is the first example of transition metal-catalyzed enaminone C-N bond conversion for the generation of a new C-C(aryl) structure.
Synthesis of Substituted Aryl Ketones by Addition of Alcohols to Alkynes Using Amberlyst-15/Ionic Liquid as a Recyclable Catalytic System
Wagh, Kishor V.,Bhanage, Bhalchandra M.
supporting information, p. 759 - 764 (2015/03/30)
A highly efficient protocol for the synthesis of substituted aryl ketones by using Amberlyst-15 immobilized in [Bmim][PF6] ionic liquid has been firstly developed. The present protocol works under metal-free, solvent-free, mild reaction conditions with 100% atom efficiency. The various aryl ketones were obtained in good to excellent yields. The developed catalytic system was recycled efficiently up to five cycles without significant loss in catalytic activity.
Ligand-free nickel-catalysed 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds
Chen, Wen,Sun, Lu,Huang, Xi,Wang, Jiayi,Peng, Yanqing,Song, Gonghua
, p. 1474 - 1482 (2015/05/19)
A simple and efficient ligand-free nickel-based catalytic system has been developed for the 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds. With catalyst loadings of 1-2 mol%, a series of 1,4-adducts from chalcones and cinnamates was obtained in moderate to excellent yields within 5-30 min under a nitrogen atmosphere and microwave irradiation. The 1,4-addition of arylboronic acids to acrylates is less efficient.
Palladium-catalyzed conjugate addition of arylsulfonyl hydrazides to α,β-unsaturated ketones
Chen, Wen,Chen, Hui,Xiao, Fuhong,Deng, Guo-Jun
, p. 4295 - 4298 (2013/08/23)
A palladium-catalyzed desulfitative-denitrogenative conjugate addition of arylsulfonyl hydrazides to α,β-unsaturated ketones is described. The reaction showed very good selectivity and tolerated a wide range of functionalities under an atmosphere of oxygen with or without the aid of a metal co-oxidant. The Royal Society of Chemistry 2013.
Palladium-catalyzed desulfitative conjugate addition of aryl sulfinic acids and direct ESI-MS for mechanistic studies
Wang, Huifeng,Li, Yaming,Zhang, Rong,Jin, Kun,Zhao, Defeng,Duan, Chunying
supporting information; experimental part, p. 4849 - 4853 (2012/07/02)
A new and efficient method for palladium(II) catalytic desulfitative conjugate addition of arylsulfinic acids with α,β-unsaturated carbonyl compound has been developed. The key reacting intermediates including aryl Pd(II) sulfinic intermediate, aryl Pd(II), and C=O-Pd complexes were captured by ESI-MS/MS, which provide new experimental evidence for the understanding of addition mechanism.
Catalytic decarboxylative alkylation of β-keto acids with sulfonamides via the cleavage of carbon-nitrogen and carbon-carbon bonds
Yang, Cui-Feng,Wang, Jian-Yong,Tian, Shi-Kai
supporting information; experimental part, p. 8343 - 8345 (2011/09/16)
An efficient decarboxylative alkylation reaction of β-keto acids with N-benzylic or N-allylic sulfonamides has been developed, for the first time, through sequential cleavage of carbon-nitrogen and carbon-carbon bonds in the presence of 10 mol% of FeCl3.
