27104-72-9

Basic information

• Product Name: ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER
• Synonyms: ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER;1-Isoquinolinecarboxylic acid methyl ester;Methyl 1-isoquinolinecarboxylate;Methyl isoquinoline-1-carboxylate
• CAS NO: 27104-72-9
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.19
• Mol File: 27104-72-9.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Density: 1.210
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER(27104-72-9)
• EPA Substance Registry System: ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER(27104-72-9)

Safety Data

• Hazardous Substances Data: 27104-72-9(Hazardous Substances Data)

Usage

General Description

ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER, also known as methyl isoquinoline-1-carboxylate, is a chemical compound commonly used in pharmaceutical research and drug development. It is a derivative of isoquinoline, a heterocyclic aromatic compound, and contains a carboxylic acid and a methyl ester functional group. ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER has been studied for its potential biological activities, including anti-inflammatory and analgesic properties. It has also been investigated for its potential use in the treatment of various diseases, including cancer and neurodegenerative disorders. Additionally, it has been used as a building block in the synthesis of other bioactive compounds. Overall, ISOQUINOLINE-1-CARBOXYLIC ACID METHYL ESTER is a versatile chemical compound with potential applications in various fields, particularly in pharmaceutical and medicinal chemistry.

Upstream product

• 67-56-1 methanol 
• 486-73-7 1-isoquinolinecarboxylic acid 
• 1262842-14-7 C₁₈H₁₉NO₄S 

Downstream Products

• 27311-63-3 1-Hydroxymethyl-isoquinoline 
• 153758-56-6 (1,2,3,4-tetrahydroisoquinolin-1-yl)methanol 
• 170486-99-4 1-(1,3-dioxolan-2-yl)-2-benzylisoquinolium bromide 
• 4444-91-1 methyl 9-hydroxy-10-oxostearate 
• 406192-81-2 isoquinoline hydrazide 
• 4494-18-2 isoquinoline-1-carbaldehyde 
• 66948-16-1 rac-2-(isoquinolin-1-yl)-1-phenylethan-2-ol 

Relevant articles and documents

Synthesis and Hofman-degradation of 1-hydroxymethyl-2,2-diemethyl-1,2,3,4-tetrahydroiso-quinolinium-ion

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Fluorescence “On-Off” chemical sensor for ultrasensitive detection of Al3+ in live cell

An efficient fluorescent probe, 3, 3-bis(4-hydroxyphenyl)-2-benzofuran-1-one-isoquinoline-1-carbohydrazide hydrazine (L), has been prepared for the selective sensing of Al3+ in DMSO-H2O (90:10, v/v) solution. The 1:2 stoichiometry of

INHIBITORS OF MLH1 AND/OR PMS2 FOR CANCER TREATMENT

The present invention relates to compounds of Formula (I) that target the MLH1 and/or PMS2 proteins that are components of the DNA Mismatch Repair (MMR) process: Formula (I) wherein R1, R2, R3, R4, R6

A dual-functional fluorescent probe for sequential determination of Cu2+/S2? and its applications in biological systems

A new acylhydrazine-derived Schiff base fluorescence probe DMI based on “ON-OFF-ON” fluorescence strategy was presented in this paper. Probe DMI could detect Cu2+ selectively and sensitively with dramatic fluorescence quenching in CH3OH-PBS (v/v = 3:7) mixed solution. Once the complex DMI-Cu2+ interacted with S2?, 10.67-folds fluorescence increase was induced via a displacement mechanism under the same experimental conditions. The corresponding detection limits for Cu2+ and S2? were calculated to be 1.52 × 10?8 M and 1.79 × 10?8 M, respectively. The structures of DMI and DMI-Cu2+ were systematically characterized by Job's plot analysis, ESI-MS, IR, X-ray diffraction and density functional theory calculations. Furthermore, fluorescence imaging in MCF-7 cells and zebrafish demonstrated the probe DMI could act as a useful tool to monitor and track intracellular Cu2+ and S2?, which was encouraged by remarkable fluorescence performance and low cytotoxicity. Importantly, the complex DMI-Cu2+ could be applied to detect corrupt blood samples, which could estimate the time of death.