27441-79-8

Upstream product

• 1871-57-4 2-chloromethyl-3-chloroprop-1-ene 
• 100-51-6 benzyl alcohol 
• 3513-81-3 2-(Hydroxymethyl)allyl alcohol 
• 100-39-0 benzyl bromide 

Downstream Products

• 145215-00-5 ethyl 1,1-bis(benzyloxymethyl)cyclopropane-2-carboxylate 
• 77356-14-0 1,3-dibenzyloxy-2-propanone 
• 774587-66-5 1-(2-benzyloxymethylallyl)cyclohexanecarboxaldehyde 
• 1058138-87-6 1-benzyl-4-methylene-2-pentylpyrrolidine 
• 1332646-37-3 C₂₃H₂₈O₄ 
• 1397441-82-5 1-isocyano-2,2-bis[2',2'-di(benzyloxymethyl)ethoxymethyl]ethane 
• 1380599-06-3 1-amino-2,2-bis[2',2'-di(benzyloxymethyl)ethoxymethyl]ethane 
• 1380599-05-2 1-azido-2,2-bis[2',2'-di(benzyloxymethyl)ethoxymethyl]ethane 
• 1380599-04-1 2,2-bis[2',2'-di(benzyloxymethyl)ethoxymethyl]ethane mesylate 
• 778592-64-6 2,2-bis[2',2'-di(benzyloxymethyl)ethyoxymethyl]ethanol 
• 1380598-98-0 2,2-bis[2',2'-di(benzyloxymethyl)ethoxymethyl]ethene 
• 145215-24-3 6-<<2,2-bis(benzyloxymethyl)cyclopropyl>amino>-4-chloro-2,5-diformamidopyrimidine 
• 145215-26-5 N-[9-(2,2-Bis-benzyloxymethyl-cyclopropyl)-6-chloro-9H-purin-2-yl]-formamide 
• 145215-29-8 9-<2,2-bis(benzyloxymethyl)cyclopropyl>guanine 

Relevant academic research and scientific papers

Convergent synthesis of dendrimers via the passerini three-component reaction

Tuning properties by programming the surface functional group composition of surface-block dendrimers has been limited to dendrimers with only two types of surface functionality (i.e., surface-diblock dendrimers). The Passerini reaction provides dendrimer

Synthesis and evaluation of a new class of tertiary alcohol based BACE-1 inhibitors

BACE-1 has emerged as one of the best characterized targets for future Alzheimer therapy. In accordance with the successful identification of masked inhibitors of HIV-1 protease, we envisioned that tert-alcohol containing transition-state mimicking struct

Convenient synthesis of pyrrolidines by amphiphilic allylation of imines with 2-methylenepropane-1,3-diols

(Chemical Equation Presented). A straightforward route: The combination of a palladium catalyst and triethylborane promotes the amphiphilic (nucleophilic-electrophilic) allylation of aldimines, prepared in situ from a wide variety of aromatic and aliphatic aldehydes and amines, with commercially available 2-methylenepropane-1,3-diols to provide pyrrolidines (see scheme).

Synthesis and biological evaluation of novel tert-azido or ten-amino substituted penciclovir analogs

tert-Azido or amino substituted penciclovir analogs, 1-3 were synthesized for the purpose of improving the efficacy and bioavailability of penciclovir and searching for novel antiviral agents. Among several methods attempted to insert an azido group into

Studies of intramolecular alkylidene carbene reactions; an approach to heterocyclic nucleoside bases

A series of investigations into the applications of intramolecular cyclisations of alkylidene carbenes are described. The insertion reaction of the carbene generated from 1,4-di(tert-butyldimethylsilyloxy)-3-benzyloxy-butane-2-one to the benzylic position

Synthesis of 2,5-dihydrofurans via alkylidene carbene insertion reactions

The insertion reaction of alkylidene carbenes is demonstrated to be an effective method for the synthesis of 2,5-dihydrofuran ring systems. The best results have been obtained on substrates containing electron-withdrawing substituents, which appear less prone to the competing rearrangement reaction. This insight has led to the development of a new method for the synthesis of the core structure of the squalestatin-zaragozic acid natural products.

Synthesis of Carbocyclic Nucleosides: Synthesis of (+/-)-2,2-Bis(hydroxymethyl)cyclopropyl Nucleosides

Treatment of 2,2-bis(benzyloxymethyl)cyclopropanecarboxylic acid 8 with ethyl chloroformate and sodium azide followed by thermolysis of the resulting keto azide 9 at 80 deg C provided the corresponding isocyanate 10, which was then converted into 2,2-bis(