2767-84-2

Usage

Chemical Properties

YELLOW POWDER

Uses

Chiral starting material.

InChI:InChI=1/C10H14O2/c1-9(2)6-4-5-10(9,3)8(12)7(6)11/h6H,4-5H2,1-3H3/t6-,10+/m0/s1

Upstream product

• 76-22-2 Camphor 
• 7519-74-6 thiocamphor 
• 17697-12-0 benzeneseleninic anhydride 
• 95589-30-3 (1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one 
• 736109-58-3 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 
• 663-17-2 camphorquinone monooxime 
• 104319-35-9 DL camphor-10-thiazine dioxide 
• 464-48-2 (1S)-camphor 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 64474-54-0 (-)-(1S,3R,4R)-3-bromocamphor 
• 76-29-9 3-bromocamphor 
• 14487-70-8 3-diazocamphor 
• 75-05-8 acetonitrile 
• 76013-16-6 3-endo-(phenylseleninyl)camphor 

Downstream Products

• 595-29-9 camphoric anhydride 
• 15210-83-0 2,2,3-trimethyl-4-oxo-cyclohexanecarboxylic acid 
• 71681-63-5 3-o-tolylimino-bornan-2-one 
• 116865-63-5 (+/-)-3-((Ξ)-3-bromo-phenylimino)-bornan-2-one 
• 71681-69-1 (+/-)-3-((Ξ)-4-bromo-phenylimino)-bornan-2-one 
• 117122-83-5 (+/-)-3-((Ξ)-2-bromo-phenylimino)-bornan-2-one 
• 110463-08-6 (+/-)-3-(3-ethoxy-phenylimino)-bornan-2-one 
• 10373-81-6 3-hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 
• 91900-73-1 m-menth-3⁽⁸⁾-ene-2,6-dione 
• 13837-85-9 1,7,7-trimethylbicyclo[2.2.1]heptane-exo,exo-2,3-diol 
• 3278-94-2 homocamphorquinoline 
• 21488-68-6 (1R)-3exo-hydroxy-bornan-2-one 
• 10373-79-2 DL-3-endo-(4-Methyl-benzyl)-3-exo-hydroxy-bornan-2-on 
• 101980-80-7 1,2,2-trimethylcyclopentyl p-methylbenzyl ketone 

Relevant academic research and scientific papers

Electropolymerization of D-A type EDOT-based monomers consisting of camphor substituted quinoxaline unit for electrochromism with enhanced performance

In this study, three novel donor-acceptor type monomers based on EDOT (3,4-ethoxylene dioxy thiophene) and quinoxaline derivates were designed and synthesized through Stille coupling reaction, and further polymerized by electrochemical polymerization for electrochromic application. Specially, a quinoxaline-based acceptor with bulky and rigid camphor group was introduced into the polyEDOT backbone, which was demonstrated to be effective for the improvement of electrochromic performance. The corresponding redox active polymers PCQ-EDOT and PCQ-DEDOT performed transparent oxidation states and robust switching stability. Polymer PCQ-EDOT showed superior electrochromic performances with high optical contrast (over 50%) at 647 nm, short switching time (around 0.5 s) and high coloration efficiency (427 cm2 C?1) under a low applied potential of 0.7 V.

Novel synthetic method of camphorquinone

The invention relates to a novel synthetic method of camphorquinone, which is a method for preparing camphorquinone from camphor in the presence of a catalyst. The invention further provides a methodfor preparing camphorquinone, which can effectively reduce the toxicity of the used catalyst and reflect the harm to the environment, and ensures a high yield of the reaction while simplifying the process flow. According to the method, clean energy microwave irradiation instead of conventional energy is utilized, so that the pollution of the reaction to the environment is greatly reduced while thereaction yield is ensured, and the purpose of green chemistry is met.

Selectively polymerizable compositions and methods of use in vivo

Otologic materials and methods are provided. For example, a cell-adhesive, biodegradable hydrogel scaffold loaded with time-released drugs for repairing chronic tympanic membrane perforations is disclosed, methods of making same and administering same are provided. This hydrogel may promote vascular in-growth and epithelial cell growth of the tympanic membrane with the purpose of closing the perforation and providing a barrier between the external and middle ear. The hydrogel is initially a liquid polymer that only gels upon exposure to specific conditions, such as exposure to light. This scaffold may simultaneously induce repair of the tympanic membrane while preventing or alleviating middle ear infection, thus filling a void in current tympanic membrane perforation therapies.

Method for producing camphorquinone by taking byproduct generated in camphor synthesis process as raw material

The invention provides a method for producing camphorquinone by taking a byproduct generated in the camphor synthesis process as a raw material, belonging to the technical field of organic synthesis.The byproduct 3-camphene ester generated in the synthesis process of camphor is used as a starting material to prepare high-purity camphorquinone through refining, saponification, dehydrogenation, condensation, hydrolysis and recrystallization steps. The method has the beneficial effects that the value of the byproduct generated in the camphor synthesis process is used, industrial wastes are reduced, wastes are changed into valuables, environmental pressure is reduced, a brand-new path for the synthesis of the camphorquinone is provided, no heavy metals are used in all process steps, truly nontoxic chemical synthesis of the camphorquinone is realized, and the method is an economic and environment-friendly production process.

PYRIDAZINE DERIVATIVES AS RORC MODULATORS

Compounds of formula (I): (I) or pharmaceutical salts thereof, wherein m, n,, p, q A, B, Ri, R2, R3, R4, R5, R6and R7are as defined herein. Also disclosed are methods of making the compounds and using the compounds as RORs modulators for treatment of inflammatory diseases such as arthritis.

A phenanthroline-derived ligand and its complexation with Pd(II): From ligand design, synthesis and Pd(II) complexes structures to its application

A novel phenanthroline-derived bis-opened-triazine ligand for selective complexation with Pd(ii) over 19 typical metals from HNO3 media was designed based on cavity modulation strategy. Structures of the three species of the Pd(ii) complexes of with the ligand were elucidated by 1H NMR titration isothermal titration calorimetry (ITC) and density functional theory (DFT) studies. ITC test and binding energy calculations demonstrated that the asymmetrical 1:1 Pd(ii)-ligand complex with a monodentate nitrate anion was the most stable among these three species of the Pd(ii) complexes. The excellent kinetics of Pd(ii) extraction with the ligand is due to its optimal conformation completely ready for metal ligation. The enhanced special extraction selectivity and fast extraction rate towards Pd(ii) achieved by the phenanthroline-derived ligand demonstrated that the effective separation of some radionuclides with smaller radius in HLW through cavity modulation strategy is a feasible approach.

SELECTIVELY POLYMERIZABLE COMPOSITIONS AND METHODS OF USE IN VIVO

Otologic materials and methods are provided. For example, a cell-adhesive, biodegradable hydrogel scaffold loaded with time-released drugs for repairing chronic tympanic membrane perforations is disclosed, methods of making same and administering same are provided. This hydrogel may promote vascular in-growth and epithelial cell growth of the tympanic membrane with the purpose of closing the perforation and providing a barrier between the external and middle ear. The hydrogel is initially a liquid polymer that only gels upon exposure to specific conditions, such as exposure to light. This scaffold may simultaneously induce repair of the tympanic membrane while preventing or alleviating middle ear infection, thus filling a void in current tympanic membrane perforation therapies.

Oxidation of terpenoid diols with chlorine dioxide. Easy preparation of α-hydroxyketones

Oxidative dehydrogenation of vicinal diols of bornane and pinane type with chlorine dioxide in dimethylformamide has yielded α-hydroxyketones with high selectivity. 3α-Hydroxy-10β-pinane-4-one has been prepared for the first time with yield of 63-65%; the

New chiral cyclopalladated complexes based on the pinane and bornane imines

2α-Hydroxypinan-3-one imino derivatives react with lithium tetrachloropalladate to form palladacycles, while similar bornane derivative undergo cyclopalladation only when treated with palladium acetate.

METHOD FOR MANUFACTURING ESTER

The present invention relates to a method for manufacturing an ester from a ketone or an aldehyde, which is a reactive substrate, by a Baeyer-Villiger oxidation reaction using hydrogen peroxide, and in this method, as a catalyst, M(BAr4)n, which is a metal borate, is used (M represents an alkali metal or an alkaline earth metal; Ar represents an aryl; and n is the same number as the valence of M). For example, when cyclohexanone was used as the reactive substrate, and Sr[B(3,5-CF3C6H3)4]2 was used as the catalyst, ε-caprolactone was obtained at an isolated yield of 82%.