27826-43-3

Basic information

• Product Name: n-butyl(4-nitrophenyl) sulfane
• Synonyms: n-butyl(4-nitrophenyl) sulfane
• CAS NO: 27826-43-3
• Molecular Formula: C₁₀H₁₃NO₂S
• Molecular Weight: 211.28
• Mol File: 27826-43-3.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: n-butyl(4-nitrophenyl) sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: n-butyl(4-nitrophenyl) sulfane(27826-43-3)
• EPA Substance Registry System: n-butyl(4-nitrophenyl) sulfane(27826-43-3)

Safety Data

• Hazardous Substances Data: 27826-43-3(Hazardous Substances Data)

Upstream product

• 109-79-5 n-butanethiol 
• 17763-80-3 para-nitrophenyl triflate 
• 100-00-5 4-chlorobenzonitrile 
• 586-78-7 para-nitrophenyl bromide 
• 542-69-8 1-iodo-butane 
• 1849-36-1 para-nitrobenzenethiol 
• 629-45-8 dibutyl disulfide 
• 350-46-9 4-Fluoronitrobenzene 
• 636-98-6 p-nitrobenzene iodide 
• 109-69-3 n-Butyl chloride 
• 109-65-9 1-bromo-butane 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 201230-82-2 carbon monoxide 
• 45797-13-5 4-nitrophenylthiolate 

Downstream Products

• 78597-96-3 4-butylsulfonylnitrobenzene 
• 76410-92-9 1-(butylsulfinyl)-4-nitrobenzene 
• 92286-68-5 4-butylsulfanyl-aniline; hydrochloride 
• 836-30-6 4-ntrophenyl(phenyl)amine 
• 51770-72-0 (4-Aminophenyl)-butyl-sulfon 

Relevant articles and documents

Exploration of the mechanism and scope of the CuI/DABCO catalysed C–S coupling reaction

A cost effective and easily available CuI/DABCO catalytic system has been developed for the C–S cross-coupling reaction. This method is extremely useful for the thioetherification of aryl and heteroaryl halides, providing excellent yields and good chemoselectivity. We have also explored the mechanism of the reaction using DFT studies.

C-S cross-coupling of aryl halides with alkyl thiols catalyzed by in-situ generated nickel(II) N-heterocyclic carbene complexes

The C-S cross-coupling of aryl halides with alkyl thiols catalyzed by in-situ generated Ni (II) N-heterocyclic carbene (NHC) complexes is investigated. Good to excellent yields can be obtained for a variety of aryl halides when using 5 mol% of the Ni (II)-NHC catalyst and 1.5 eq. of KOtBu. Both the electronic and steric effects of the NHC ligands on the catalytic performance of Ni (II)-NHC, as well as the electronic effects of aryl halides on coupling reactivity are examined. The mechanism for Ni (II)-NHC catalyzed coupling reactions is also discussed.

Nucleophilic Aromatic Substitution Reactions in Water Enabled by Micellar Catalysis

Given the huge dependence on dipolar, aprotic solvents such as DMF, DMSO, DMAc, and NMP in nucleophilic aromatic substitution reactions (SNAr), a simple and environmentally friendly alternative is reported. Use of a "benign-by-design" nonionic surfactant, TPGS-750-M, in water enables nitrogen, oxygen, and sulfur nucleophiles to participate in SNAr reactions. Aromatic and heteroaromatic substrates readily participate in this micellar catalysis, which takes place at or near ambient temperatures.