Welcome to LookChem.com Sign In|Join Free
  • or
3-Methyl-4-[3-(pyridin-3-ylmethylamino)propoxy]-1-benzofuran-2-carboxylic acid ethyl ester is a complex organic compound with the molecular formula C20H22N2O4. It is a derivative of benzofuran, a heterocyclic aromatic compound, and features a pyridine ring attached to a propoxy chain. The molecule contains a methyl group at the 3-position and an ethyl ester group at the 2-position of the benzofuran ring. 3-Methyl-4-[3-(pyridin-3-ylmethylamino)propoxy]-1-benzofuran-2-carboxylic acid ethyl ester is known for its potential applications in pharmaceutical research, particularly as a precursor or intermediate in the synthesis of various drugs and bioactive molecules. Its chemical structure and properties make it a promising candidate for further exploration in the development of new therapeutic agents.

279230-20-5

Post Buying Request

279230-20-5 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

279230-20-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 279230-20-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,9,2,3 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 279230-20:
(8*2)+(7*7)+(6*9)+(5*2)+(4*3)+(3*0)+(2*2)+(1*0)=145
145 % 10 = 5
So 279230-20-5 is a valid CAS Registry Number.

279230-20-5Relevant academic research and scientific papers

Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase

Masubuchi, Miyako,Ebiike, Hirosato,Kawasaki, Ken-Ichi,Sogabe, Satoshi,Morikami, Kenji,Shiratori, Yasuhiko,Tsujii, Shinji,Fujii, Toshihiko,Sakata, Kiyoaki,Hayase, Michiko,Shindoh, Hidetoshi,Aoki, Yuko,Ohtsuka, Tatsuo,Shimma, Nobuo

, p. 4463 - 4478 (2007/10/03)

The C-4 side chain modification of lead compound 1 has resulted in the identification of a potent and selective Candida albicans N-myristoyltransferase (CaNmt) inhibitor RO-09-4609, which exhibits antifungal activity against C. albicans in vitro. Further

Bicyclic compounds

-

, (2008/06/13)

The present invention is directed to new bicyclic compounds of the formula [I], and pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, R5, R6, R7, Q1Q2and Q3are as defined in the claims. The compounds have N-myristoyltransferase inhibitory and antifungal activity.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1

Masubuchi, Miyako,Kawasaki, Ken-ichi,Ebiike, Hirosato,Ikeda, Yoshihiko,Tsujii, Shinji,Sogabe, Satoshi,Fujii, Toshihiko,Sakata, Kiyoaki,Shiratori, Yasuhiko,Aoki, Yuko,Ohtsuka, Tatsuo,Shimma, Nobuo

, p. 1833 - 1837 (2007/10/03)

Potent and selective Candida albicans N-myristoyltransferase (CaNmt) inhibitors have been identified through optimization of a lead compound 1 discovered by random screening. The inhibitor design is based on the crystal structure of the CaNmt complex with compound (S)-3 and structure-activity relationships (SARs) have been clarified. Modification of the C-4 side chain of 1 has led to the discovery of a potent and selective CaNmt inhibitor 11 (RO-09-4609), which exhibits antifungal activity against C. albicans in vitro.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 279230-20-5