28896-49-3

Basic information

• Product Name: 4-IODOPHENYL ETHER
• Synonyms: 4,4'-Diiododiphenyl ether;Benzene, 1,1'-oxybis(4-iodo-;Bis(p-iodophenyl) ether;Ether, bis(p-iodophenyl);ether,bis(p-iodophenyl);4-IODOPHENYL ETHER;2-Iodo-4,5-dimethylnitrobenzene;Benzene, 1,1'-oxybis[4-iodo- Ether, bis(p-iodophenyl)
• CAS NO: 28896-49-3
• Molecular Formula: C₁₂H₈I₂O
• Molecular Weight: 422
• Mol File: 28896-49-3.mol
• Article Data: 26

Chemical Properties

• Melting Point: 43-45°C
• Boiling Point: 377.5 °C at 760 mmHg
• Flash Point: 182.1 °C
• Appearance: /
• Density: 2.066 g/cm³
• Vapor Pressure: 0.00071mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 4-IODOPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODOPHENYL ETHER(28896-49-3)
• EPA Substance Registry System: 4-IODOPHENYL ETHER(28896-49-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 28896-49-3(Hazardous Substances Data)

Usage

General Description

4-Iodophenyl Ether, also known as p-Iodophenyl Ether or 4-Iododiphenyl Ether, is a compound distinguished by the presence of an iodine atom and an ether group. Its chemical formula is C12H9IO. This chemical has a molar mass of 344.10 g/mol. It's not typically used in regular consumer products due to its hazardous nature, and is generally used in scientific or industrial contexts. The compound is characterized by its relatively high reactivity due to the presence of the iodine atom. Care should be taken when handling this material as it can cause harm to the eyes, respiratory system, and skin upon exposure. It is recommended to have proper training to handle this chemical safely.

InChI:InChI=1/C12H9IO/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9H

Upstream product

• 101-84-8 diphenylether 
• 7790-99-0 Iodine monochloride 
• 64-19-7 acetic acid 
• 620-88-2 4-nitrophenyl phenyl ether 
• 21969-05-1 1-(4-nitrophenoxy)-4-iodobenzene 
• 624-38-4 para-diiodobenzene 
• 58518-73-3 4-(4-iodo-phenoxy)-aniline 
• 2974-94-9 4-phenoxyiodobenzene 
• 139-59-3 4-phenoxyanilin 
• 100-00-5 4-chlorobenzonitrile 
• 860578-02-5 acetic acid-[4-(4-iodo-phenoxy)-anilide] 
• 6312-87-4 p-phenoxyacetanilide 

Downstream Products

• 101-80-4 4,4'-oxydiphenylene diamine 
• 943035-24-3 4-[4-(4-iodophenoxy)phenyl]piperazine-1-carboxylic acid tert-butyl ester 
• 1965-09-9 4,4'-dihydroxydiphenyl ether 
• 855126-43-1 3-[4-(4-iodo-phenoxy)-phenoxy]-1-aza-bicyclo[2.2.2]octane 
• 15051-28-2 4,4'-bis[4-(4-hydroxyphenoxy)phenoxy]diphenyl ether 
• 5024-81-7 4,4'-(bis(p-hydroxyphenoxy))diphenyl ether 
• 21368-80-9 1,1'-oxybis(4-ethynylbenzene) 
• 5024-85-1 4,4'-bis(4-dimethoxyphenoxyl)phenyl ether 
• 916265-23-1 4,4'-bis[4-{4-(methoxymethoxy)phenoxy}phenoxy]diphenyl ether 
• 83281-31-6 4,4'-distyryldiphenyl ether 
• 17541-14-9 4,4'-bis(3-hydroxy-3-methylbutynyl)diphenyl ether 

Relevant articles and documents

R4NHal/NOHSO4: A Usable System for Halogenation of Isoxazoles, Pyrazoles, and beyond

A new convenient and versatile halogenating system (R4NHal/NOHSO4), giving straightforward and general access to halogenated 3,5-diaryl- and alkylarylisoxazoles, pyrazoles and electron-rich benzenes from the corresponding scaffolds, is suggested. The method provides excellent regioselectivity, scalability to the gram scale, and a broad scope for both aromatics and halogens. A three-step, one-pot reaction protocol was developed, and a series of 3,5-diaryl-4-haloisoxazoles has been efficiently synthesized from 1,2-diarylcyclopropanes under suggested nitrosating-halogenating conditions.

COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES

The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases

IBX-I2 redox couple for facile generation of IOH and I +: Expedient protocol for iodohydroxylation of olefins and iodination of aromatics

(Chemical Equation Presented) IBX is readily reduced to IBAin the presence of molecular iodine in DMSO to generate hypoiodous acid (IOH), which reacts with a variety of olefins as well as R, β-unsaturated ketones leading to their respective iodohydrins with anti stereochemistry. The same redox chemistry in acetonitrile containing TFA produces iodonium ions for facile iodination of a variety of aromatic compounds in respectable isolated yields.