289903-56-6

Basic information

• Product Name: 4-(2-azidoethoxy)-3-methoxybenzylisothiocyanate
• Synonyms: 4-(2-azidoethoxy)-3-methoxybenzylisothiocyanate
• CAS NO: 289903-56-6
• Molecular Weight: 264.308
• Mol File: 289903-56-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2-azidoethoxy)-3-methoxybenzylisothiocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-azidoethoxy)-3-methoxybenzylisothiocyanate(289903-56-6)
• EPA Substance Registry System: 4-(2-azidoethoxy)-3-methoxybenzylisothiocyanate(289903-56-6)

Safety Data

• Hazardous Substances Data: 289903-56-6(Hazardous Substances Data)

Upstream product

• 102368-13-8 1,1'-Thiocarbonyldi-2(1H)-pyridone 
• 289903-50-0 tert-butyl N-[4-(2-azidoethoxy)-3-methoxybenzyl]carbamate 
• 130972-90-6 tert-butyl N-[4-(2-bromoethoxy)-3-methoxybenzyl]carbamate 
• 130972-89-3 (4-hydroxy-3-methoxybenzyl)carbamic acid tert-butyl ester 
• 7149-10-2 vanillylamine hydrochloride 

Downstream Products

• 289903-60-2 2,2-Dimethyl Propionic Acid 2-{3-[4-(2-Azidoethoxy)-3-methoxybenzyl]thioureido Methyl}-3-(4-t-butylphenyl)propyl Ester 
• 289903-58-8 2,2-Dimethyl Propionic Acid 2-{3-[4-(2-Azidoethoxy)-3-methoxybenzyl]thioureido Methyl}-3-(3,4-dimethylphenyl)propyl ester 

Relevant articles and documents

Phenolic modification as an approach to improve the pharmacology of the 3-acyloxy-2-benzylpropyl homovanillic amides and thioureas, a promising class of vanilloid receptor agonists and analgesics

In order to improve the analgesic activity and pharmacokinetics of thioureas 2 and 3, which we previously developed as potent vanilloid receptor (VR) agonists, we prepared and characterized phenolic modifications of them and of their amide surro-gates (7, 8). The aminoethyl analogue of the amide template 13 was a potent analgesic with an EC50 =0.96 μg/kg in the AA-induced writhing test and with better in vivo stability than the parent phenol. Copyright