29265-81-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Chloro-3-(1-phenyl-vinyl)-benzene is used as an intermediate in the synthesis of pharmaceuticals for its ability to be a key component in the creation of various medicinal compounds.
Used in Dye Industry:
In the dye industry, 1-chloro-3-(1-phenyl-vinyl)-benzene is used as a precursor for the production of dyes, contributing to the development of colorants for various applications.
Used in Organic Chemicals Production:
1-Chloro-3-(1-phenyl-vinyl)-benzene is utilized as a building block in the production of other organic chemicals, highlighting its versatility in chemical synthesis.

Upstream product

• 1016-78-0 3-chlorobenzophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 98-86-2 acetophenone 
• 14428-98-9 N-benzyl-N-(1-phenylethylidene)amine 
• 90006-76-1 3-methyl-3-phenyl-diaziridine 
• 63503-60-6 3-chlorophenylboronic acid 
• 63269-86-3 3-methyl-3-phenyl-3H-diazirine 
• 100-58-3 phenylmagnesium bromide 
• 107776-74-9 1-(3-chloro-phenyl)-1-phenyl-ethanol 
• 99-02-5 3'-Chloroacetophenone 
• 98-81-7 1-bromovinylbenzene 
• 62460-99-5 (E)-4-methyl-N′-(1-phenylethylidene)benzenesulfonohydrazide 

Downstream Products

• 1355956-63-6 C₂₆H₂₁ClSi 
• 1355956-46-5 C₂₆H₂₃ClSi 
• 1016-78-0 3-chlorobenzophenone 
• 1286278-98-5 4-(3-chlorophenyl)-4-phenylbutan-2-one 

Relevant academic research and scientific papers

Halogenation of 1,1-diarylethylenes by N-halosuccinimides

An efficient method for the preparation of 2,2-diarylvinyl halides from the corresponding 1,1-diarylethylenes has been developed. N-Halosuccinimides (N-bromosuccinimide or N-chlorosuccinimide) were used as the halogenation reagents. The practicability of this method is highlighted by its simple operation, broad substrate scope and capability for large-scale reaction.

Photocatalytic, Phosphoranyl Radical-Mediated N-O Cleavage of Strained Cycloketone Oximes

A photoinduced, phosphoranyl radical-mediated protocol for the direct N-O cleavage of strained cycloketone oximes via a polar/SET crossover process was developed for the first time. This visible-light-driven direct N-O activation mode for oxime offers beneficial features such as streamlined synthetic process and versatile photochemical reactivities. Consequently, the alkenes and α-trifluoromethyl alkenes with varied electronic and structural features acted as competent radical receptors in this protocol, enabling facile accesses to a range of elongated cyano and/or gem-difluoroalkene-bearing compounds.

Method for synthesizing alpha,beta-unsaturated selenium compound

The invention belongs to the field of organic selenium chemistry, and particularly relates to a method for synthesizing an alpha,beta-unsaturated selenium compound. The compound is synthesized by using an aryl boronic acid compound, elemental selenium and a diarylethene compound as reaction substrates. The method avoids toxic selenium-mercury reagents and toxic selenide reagents, conforms to the modern green development concept, and provides a green and economical method for synthesizing unsaturated selenium compounds in the future.

Metal-free oxidative cross-coupling of diazirines with arylboronic acids

We report herein a metal-free cross-coupling of diazirines with arylboronic acids under oxidative conditions. The reaction affords a series of substituted olefins. It is proposed that the interaction between the nitrogen on diazirine with arylboronic acid plays a key role in this transformation.

Olefin-assisted iron-catalyzed alkylation of aryl chlorides

A selective and operationally simple ironcatalyzed cross-coupling of aryl chlorides with alkylmagnesium halides has been developed. The reaction tolerates various functional groups and exhibits high chemoselectivity even in the presence of aryl bromides. Mechanistic studies indicate the essential role of the olefin substituent for substrate activation. Competing polymerization and reduction are effectively suppressed.

General and practical one-pot synthesis of dihydrobenzosiloles from styrenes

A one-pot synthesis of dihydrobenzosiloles from styrenes has been developed. The reaction involves the nickel-catalyzed hydrosilylation of styrene with diphenylsilane, followed by the iridium-catalyzed dehydrogenative cyclization. This method is efficient for both electron-rich and -deficient styrenes and exhibits good functional group tolerance, as well as excellent regioselectivity. The forming dihydrobenzosiloles can be efficiently converted into valuable benzosiloles or 2-hydroxyphenethyl alcohols.

Pd-catalyzed oxidative cross-coupling of N-tosylhydrazones with arylboronic acids

The Pd-catalyzed reaction of N-tosylhydrazones and arylboronic acids provides olefin derivatives. This oxidative cross-coupling is suggested to proceed through a migratory insertion process of a Pd carbene intermediate.