29618-30-2

Basic information

• Product Name: Benzenepropanamide, a-(benzoylamino)-N-phenyl-, (S)-
• CAS NO: 29618-30-2
• Molecular Formula: C22H20N2O2
• Molecular Weight: 344.413
• Mol File: 29618-30-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, a-(benzoylamino)-N-phenyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, a-(benzoylamino)-N-phenyl-, (S)-(29618-30-2)
• EPA Substance Registry System: Benzenepropanamide, a-(benzoylamino)-N-phenyl-, (S)-(29618-30-2)

Safety Data

• Hazardous Substances Data: 29618-30-2(Hazardous Substances Data)

Upstream product

• 5874-61-3 4-benzyl-2-phenyl-2-oxazolin-5-one 
• 62-53-3 aniline 
• 2566-22-5 DL-N-benzoylphenylalanine 
• 5426-73-3 2-amino-N,3-diphenylpropanamide 
• 65-85-0 benzoic acid 
• 1161-13-3 N-Cbz-L-Phe 
• 63-91-2 L-phenylalanine 
• 5426-73-3 L-phenylalanineanilide 
• 98-88-4 benzoyl chloride 
• 2566-22-5 N-benzoyl-L-phenylalanine 
• 555-48-6 2-amino-N-phenyl-acetamide 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 113035-40-8 N²-<(tert-butoxy)carbonyl>-L-phenylalanine phenylamide 
• 857770-81-1 C₁₅H₁₆N₂O*2ClH 

Downstream Products

• 952029-46-8 C₂₂H₂₄N₂ 
• 63-91-2 L-phenylalanine 

Relevant articles and documents

Synthesis of new C3 symmetric amino acid- and aminoalcohol-containing chiral stationary phases and application to HPLC enantioseparations

We recently reported a new C3-symmetric (R)-phenylglycinol N-1,3,5-benzenetricarboxylic acid-derived chiral high-performance liquid chromatography (HPLC) stationary phase (CSP 1) that demonstrated better results as compared to a previously described N-3,5-dintrobenzoyl (DNB) (R)-phenylglycinol-derived CSP. Over a decade ago, (S)-leucinol, (R)-phenylglycine, and (S)-leucine derivatives were used as the starting materials of 3,5-DNB-based Pirkle-type CSPs for chiral separation. In this study, three new C3-symmetric CSPs (CSP 2, 3, and 4) were prepared by combining the ideas and results mentioned above. Here we describe the synthetic procedures and applications of the new C3-symmetric CSPs (CSP 2–CSP 4).

ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES

The invention provides compounds having activity as bacterial RNA polymerase inhibitors and antibacterial agents, as well as compositions comprising the compounds and methods for their use. Specifically, phenylalanineamide and tyrosinamide compounds are disclosed that have inhibitory activity toward mycobacterium tuberculosis RNA polymerase. Use of these compounds in the treatment o prevention of M. tuberculosis infections in a mammal, is disclosed.

Pd-catalyzed enantioselective synthesis of quaternary α-amino acid derivatives using a phenylalanine-derived P-chirogenic diaminophosphine oxide

A Pd-catalyzed enantioselective synthesis of quaternary α-amino acid derivatives using a phenylalanine-derived P-chirogenic diaminophosphine oxide is described. Asymmetric allylic substitution using acyclic β-keto esters with a nitrogen functional group at the α-carbon as prochiral nucleophiles proceeded in the presence of 5 mol % of Pd catalyst, 10 mol % of chiral diaminophosphine oxide 1j, BSA, and appropriate additives, affording the corresponding quaternary α-amino acid derivatives in excellent yield and in up to 92% ee.