2963-65-7

Basic information

• Product Name: 5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE
• Synonyms: 1H-BENZIMIDAZOLE, 6-METHYL-2-PHENYL-;1H-BenziMidazole, 6-Methyl-2-phenyl-1H-BenziMidazole, 5-Methyl-2-phenyl- (9CI);5-Methyl-2-phenylbenziMidazole, 95%;5-Methyl-2-phenyl-1H-benzoimidazole;5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE
• CAS NO: 2963-65-7
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.26
• Mol File: 2963-65-7.mol
• Article Data: 160

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE(2963-65-7)
• EPA Substance Registry System: 5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE(2963-65-7)

Safety Data

• Hazardous Substances Data: 2963-65-7(Hazardous Substances Data)

Usage

General Description

5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE is a chemical compound with the molecular formula C16H14N2. It is a benzimidazole derivative with a methyl group attached to the 5th carbon and a phenyl group attached to the 2nd carbon of the benzene ring. 5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE has been studied for its potential medicinal properties and has shown to exhibit diverse biological activities, including anti-cancer, anti-inflammatory, and anti-microbial effects. It has also been investigated for its potential use in the development of new pharmaceutical drugs. This chemical has drawn interest for its unique structural features and potential therapeutic applications.

Upstream product

• 5467-06-1 N,N'-(4-methyl-o-phenylene)-bis-benzamide 
• 1859-00-3 N-(4-methylphenyl)benzamidine 
• 53476-33-8 2'-amino-4'-methylbenzanilide 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 36954-50-4 N-(4-methylphenyl)-benzamide oxime 
• 5023-82-5 N-((methylsulfonyl)oxy)benzimidoyl chloride 
• 106-49-0 p-toluidine 
• 1224442-15-2 C₁₄H₁₃N₃O₂ 
• 610-39-9 3,4-Dinitrotoluene 
• 707-07-3 orthobenzoic acid trimethyl ester 
• 578-46-1 5-methyl-2-nitroaniline 
• 89-62-3 4-methyl-2-nitroaniline 
• 100-52-7 benzaldehyde 

Downstream Products

• 1313402-11-7 5-methyl-1-methanesulphinylmethyl-2-phenyl-1H-benzimidazole 
• 1313401-96-5 5-methyl-1-methylsulphanylmethyl-2-phenyl-1H-benzimidazole 
• 66630-70-4 2-phenyl-1H-1,3-benzimidazole-5-carboxylic acid 
• 24781-11-1 1-benzyl-6-methyl-2-phenyl-1H-benzo[d]imidazole 

Relevant articles and documents

AN EFFICIENT PREPARATION OF 4-ARYLMETHYLISOXAZOL-5-ONES BY SELECTIVE REDUCTION OF THE 4-ARYLMETHYLENEISOXAZOL-5-ONES

An efficient selective reduction of the exocyclic double bond of the 4-arylmethyleneisoxazol-5-ones with o-phenylenediamines and aldehydes is described. 4-arylmethylisoxazol-5-ones are produced in high yields together with comparable quantities of benzimidazoles.

One-Pot Transformation of Lignin and Lignin Model Compounds into Benzimidazoles

It is a challenging task to simultaneously achieve selective depolymerization and valorization of lignin due to their complex structure and relatively stable bonds. We herein report an efficient depolymerization strategy that employs 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as oxidant/catalyst to selectively convert different oxidized lignin models to a wide variety of 2-phenylbenzimidazole-based compounds in up to 94 % yields, by reacting with o-phenylenediamines with varied substituents. This method could take full advantage of both Cβ and/or Cγ atom in lignin structure to furnish the desirable products instead of forming byproducts, thus exhibiting high atom economy. Furthermore, this strategy can effectively transform both the oxidized hardwood (birch) and softwood (pine) lignin into the corresponding degradation products in up to 45 wt% and 30 wt%, respectively. Through a “one-pot” process, we have successfully realized the oxidation/depolymerization/valorization of natural birch lignin at the same time and produced the benzimidazole derivatives in up to 67 wt% total yields.

Cobalt ferrite magnetic nanoparticles as highly efficient catalyst for the mechanochemical synthesis of 2-aryl benzimidazoles

A highly efficient magnetically separable nano cobalt ferrite catalyst was synthesized via the sol-gel auto combustion method, characterized by powder XRD, SEM, TEM, UV–Visible, FT-IR, magnetic study, and BET isotherm analysis. The synthesized material was found to be an efficient heterogeneous Lewis acid catalyst for the synthesis of 2-aryl benzimidazole derivatives via solvent-free mechanochemical synthesis. The notable features of this new protocol include solvent-free reaction, cost-effectiveness, good yields, and environmental friendliness to afford the products within a short reaction time along with easy recovery and reuse of the nano catalyst.