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Benzoylcholine chloride is a synthetic chemical compound derived from choline and benzoyl chloride. It is a specific competitive inhibitor of cholinesterase enzymes and is widely used in research and clinical studies. Benzoylcholine chloride plays a significant role in the field of neuroscience, where it is utilized to study the function of cholinergic neurotransmission in both the central and peripheral nervous systems. Its inhibitory effects on cholinesterase enzymes make it a valuable tool for investigating the physiological and pharmacological actions of acetylcholine in the nervous system. Furthermore, benzoylcholine chloride has been explored for its potential therapeutic applications in treating various neurological disorders, including Alzheimer's disease.

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  • 2964-09-2 Structure
  • Basic information

    1. Product Name: BENZOYLCHOLINE CHLORIDE
    2. Synonyms: (2-hydroxyethyl)trimethylammoniumchloridebenzoate;2-(benzyloxy)-n,n,n-trimethylethanaminiumchloride;ammonium,(2-hydroxyethyl)trimethyl-,chloride,benzoate;choline,chloride,benzoate;N-BENZOYLCHOLINE CHLORIDE;BENZOYLCHOLINE CHLORIDE;2-benzoyloxyethyltrimethylammonium chloride
    3. CAS NO:2964-09-2
    4. Molecular Formula: C12H18NO2*Cl
    5. Molecular Weight: 243.73
    6. EINECS: 221-000-9
    7. Product Categories: Ammonium Chlorides (Quaternary);Quaternary Ammonium Compounds
    8. Mol File: 2964-09-2.mol
  • Chemical Properties

    1. Melting Point: 204-208 °C
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. Water Solubility: almost transparency
    10. Sensitive: Hygroscopic
    11. BRN: 3919727
    12. CAS DataBase Reference: BENZOYLCHOLINE CHLORIDE(CAS DataBase Reference)
    13. NIST Chemistry Reference: BENZOYLCHOLINE CHLORIDE(2964-09-2)
    14. EPA Substance Registry System: BENZOYLCHOLINE CHLORIDE(2964-09-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 22-24/25
    4. WGK Germany: 3
    5. RTECS: GA0830000
    6. F: 3
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 2964-09-2(Hazardous Substances Data)

2964-09-2 Usage

Uses

Used in Neuroscience Research:
Benzoylcholine chloride is used as a research tool for studying the role of cholinergic neurotransmission in the central and peripheral nervous systems. Its ability to inhibit cholinesterase enzymes allows researchers to investigate the physiological and pharmacological actions of acetylcholine, providing insights into the functioning of the nervous system.
Used in Clinical Studies:
In clinical studies, benzoylcholine chloride is employed as a specific competitive inhibitor of cholinesterase enzymes. This property makes it a valuable agent for understanding the effects of cholinesterase inhibition on various physiological processes and for evaluating the potential therapeutic benefits of such inhibition.
Used in Drug Development for Neurological Disorders:
Benzoylcholine chloride is used as a potential therapeutic agent in the development of treatments for neurological disorders, such as Alzheimer's disease. Its inhibitory effects on cholinesterase enzymes may help improve cognitive function and slow the progression of neurodegenerative diseases by enhancing cholinergic neurotransmission.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, benzoylcholine chloride is utilized as a key intermediate in the synthesis of various drugs targeting the cholinergic system. Its ability to inhibit cholinesterase enzymes makes it a valuable component in the development of medications aimed at treating cognitive impairments and other neurological conditions.
Used in Toxicology Studies:
Benzoylcholine chloride is also used in toxicology studies to evaluate the potential toxic effects of cholinesterase inhibition on various organisms. This information is crucial for understanding the safety profile of drugs that target the cholinergic system and for developing strategies to mitigate potential adverse effects.

Check Digit Verification of cas no

The CAS Registry Mumber 2964-09-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,6 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2964-09:
(6*2)+(5*9)+(4*6)+(3*4)+(2*0)+(1*9)=102
102 % 10 = 2
So 2964-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H18NO2.ClH/c1-13(2,3)9-10-15-12(14)11-7-5-4-6-8-11;/h4-8H,9-10H2,1-3H3;1H/q+1;/p-1

2964-09-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-benzoyloxyethyl(trimethyl)azanium,chloride

1.2 Other means of identification

Product number -
Other names 2-(benzoyloxy)-n,n,n-trimethylethanaminium chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2964-09-2 SDS

2964-09-2Relevant articles and documents

Cavitand templated catalysis of acetylcholine

Zelder, Felix H.,Rebek Jr., Julius

, p. 753 - 754 (2006)

A Zn-salen-modified cavitand templates the catalytic formation of acetylcholine from choline and acetic anhydride. The Royal Society of Chemistry 2006.

Catalytic application of zinc complex of oxygen depleted 1,3-bis(pyrazole)-p-tert-butylcalix[4]arene

Sinha, Anshu Kumar,Vigalok, Arkadi,Rawat, Varun

supporting information, p. 796 - 799 (2019/02/14)

In this paper we have described the synthesis and coordination properties of monometallic Zinc complex of oxygen depleted bis(pyrazole)-p-tert-butylcalix[4]arene ligand. We also present the catalytic activity of the Zinc–bis(pyrazole) complex, in acetylation of alcohols and lactide polymerization.

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