39252-69-2

Basic information

• Product Name: ETHYL 2-IODOBENZOATE
• Synonyms: 2-IODOETHYL BENZOATE;BENZOIC ACID 2-IODOETHYL ESTER;ETHYL 2-IODOBENZOATE;ETHYL O-IODOBENZOATE;RARECHEM AL BI 0562;Benzoicacidiodoethylester;o-Iodobenzoic acid ethyl ester
• CAS NO: 39252-69-2
• Molecular Formula: C₉H₉IO₂
• Molecular Weight: 276.07
• Product Categories: Acids & Esters;Iodine Compounds
• Mol File: 39252-69-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 163-165°C 23mm
• Flash Point: 134.7 °C
• Appearance: /
• Density: 1.67
• Refractive Index: 1.5700-1.5850
• CAS DataBase Reference: ETHYL 2-IODOBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-IODOBENZOATE(39252-69-2)
• EPA Substance Registry System: ETHYL 2-IODOBENZOATE(39252-69-2)

Safety Data

• Hazard Codes: C
• Safety Statements: 24/25
• Hazardous Substances Data: 39252-69-2(Hazardous Substances Data)

Usage

General Description

ETHYL 2-IODOBENZOATE is a chemical compound with the molecular formula C9H9IO2. It is a white crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The ester group in the molecule makes it suitable for use as a flavor and fragrance ingredient as well. It is also used as a reagent in organic synthesis and as a building block in the production of other organic compounds. ETHYL 2-IODOBENZOATE is known to be harmful if swallowed or inhaled, and may cause skin and eye irritation, so proper safety precautions should be taken when handling this chemical.

Upstream product

• 936-51-6 2-phenyl-1,3-dioxolane 
• 16029-98-4 trimethylsilyl iodide 
• 94-33-7 C₉H₁₀O₃ 
• 624-76-0 Iodoethanol 
• 644-32-6 dibenzoyl disulfide 
• 98-88-4 benzoyl chloride 
• 100-52-7 benzaldehyde 
• 107-21-1 ethylene glycol 
• 939-55-9 2-chloroethyl benzoate 

Downstream Products

• 93-89-0 benzoic acid ethyl ester 
• 7553-56-2 iodine 
• 871026-10-7 2-(4-chloro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)ethyl benzoate 
• 871023-64-2 2-[7-(methylthio)-2H-pyrazolo[4,3-d]pyrimidin-2-yl]ethyl benzoate 
• 871023-63-1 2-[7-(methylthio)-1H-pyrazolo[4,3-d]pyrimidin-1-yl]ethyl benzoate 
• 1236147-18-4 3-((trimethylsilyl)methyl)but-3-enyl benzoate 
• 871026-52-7 2-[(2-bromoethyl)thio]ethyl benzoate 
• 871026-53-8 2-{[2-(4-chloro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)ethyl]thio}ethyl benzoate 
• 1383853-68-6 N-[5-cyclopropyl-3-(5,6-dihydro-4H-1,2,4-oxadiazin-3-yl)-2-(4-fluorophenyl)-1-benzofuran-6-yl]-N-(2-hydroxyethyl)methanesulfonamide 
• 1383853-36-8 N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(1H-imidazol-2-yl)-1-benzofuran-6-yl]-N-(2-hydroxyethyl)methanesulfonamide 
• 1239500-47-0 2-({2-methyl-3-[4-phenyl-5-(4H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridin-5-yl}oxy)ethanol 

Relevant articles and documents

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Total synthesis of enigmazole a from cinachyrella enigmatica. Bidirectional bond constructions with an ambident 2,4-disubstituted oxazole synthon

The first total synthesis of the cytotoxic marine macrolide enigmazole A has been completed in 22 steps (longest linear sequence). The sensitive, densely functionalized 2,4-disubstituted oxazole fragment was constructed using an efficient Negishi-type cou

β-Functionalised radicals in organic synthesis: 2-Acyloxyalkyl radicals from 2-acyloxyalkyl iodides by the tin route

The reaction of iodoesters 1a-c with electrophilic olefins 2a-d and in situ generated tributyltin hydride (from a substoichiometric amount of tributyltin chloride and an excess of sodium borohydride) in the presence of a catalytic amound of AIBN in ethanol at 0 to 20°C yields the expected coupling products 3aa-3cd. Products 4 resulting from an iodine/hydrogen exchange are also obtained as by-products in variable amounts. The stereochemistry of the coupling reaction is studied: starting from trans-2-iodocyclohexyl acetate (1d) and methyl acrylate (2a) a 1/3 mixture of the corresponding cis/trans diastereoisomers is obtained. This result indicates that the corresponding radical coupling is not stereospecific.