29786-93-4

Upstream product

• 109-65-9 1-bromo-butane 
• 109-69-3 n-Butyl chloride 
• 629-35-6 dibutylmercury 
• 71-43-2 benzene 
• 60-29-7 diethyl ether 
• 1643-19-2 tetrabutylammomium bromide 
• 7439-93-2 lithium 
• 917-64-6 methyl magnesium iodide 
• 62735-89-1 α-chloro-nitroso-2,2,6,6-tetramethylcyclohexane 
• 5432-85-9 4-isopropyl-cyclohexanone 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 2744-08-3 decahydroisoquinoline 
• 681-84-5 tetramethylorthosilicate 
• 27484-93-1 (C₄H₉)2BSB(C₄H₉)2 

Downstream Products

• 109-79-5 n-butanethiol 
• 1613-46-3 butyl propyl sulfide 
• 867129-71-3 1-butylsulfanyl-3-propylsulfanyl-propane 
• 217-59-4 triphenylene 
• 477-75-8 triptycene 
• 1657-60-9 2,2-dimethyl-1,1-diphenyl-propan-1-ol 
• 110-83-8 cyclohexene 
• 1578-33-2 2-furyltrimethylsilane 
• 2786-07-4 2-thienyl lithium 
• 18245-28-8 2-(trimethylsilyl)thiophene 
• 5058-19-5 2-butylpyridine 
• 41806-40-0 1-methyl-1H-imidazole-5-carboxylic acid 
• 20485-43-2 1-methyl-2-imidazolecarboxylic acid 
• 16034-46-1 1-methyl-1H-pyrazole-5-carboxylic acid 

Relevant academic research and scientific papers

STERIC EFFECTS IN SYSNTHESIS - STERIC LIMITS TO THE ALKYLATION OF NITRILES AND CARBOXYLIC ACIDS

The steric limits to the alkylation of aliphatic nitriles and carboxylic acids have been investigated in some detail.For the experimental conditions considered (ionization by i-Pr2NLi in THF followed by alkylation with RI/THF/HMPA) the most hindered nitriles R-CN and carboxylic acids R-CO2H have the same secondary alkyl group R=t-BuiPrCH-, but different tertiary, i.e.R=t-BuiPrEtC- or i-Pr3C- for RCN and R=Et2MeC for RCO2H.A comparison of the relative merits of alkylation of esters, carboxylic acids, and nitriles is considered.

Inhibitors of viral replication, their process of preparation and their therapeutical uses

The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.

Fine-tuning the oxidative ability of persistent radicals: Electrochemical and computational studies of substituted 2-pyridylhydroxylamines

N-tert-Butyl-N-2-pyridylhydroxylamines were synthesized from 2-halopyridines and 2-methyl-2-nitrosopropane using magnesium-halogen exchange. The use of Turbo Grignard generated the metallo-2-pyridyl intermediate more reliably than alkyllithium reagents. The hydroxylamines were characterized using NMR, electrochemistry, and density functional theory. Substitution of the pyridyl ring in the 3-, 4-, and 5-positions was used to vary the potential of the nitroxyl/oxoammonium redox couple by 0.95 V. DFT computations of the electrochemical properties agree with experiment and provide a toolset for the predictive design of pyridyl nitroxides.

Catalyst component, catalyst for olefin polymerization, and process for producing olefin polymer using catalyst

A polymer having high catalyst activity, excellent hydrogen response, high stereoregularity and high yield can be obtained by polymerizing olefins in the presence of a catalyst for olefin polymerization comprising (A) a solid catalyst component containing magnesium, titanium, a halogen, and an electron donor compound, (B) an organoaluminum compound shown by the formula R6pAlQ3-p(R1R2N)m, and (C) an aminosilane compound shown by the formula (R3HN)nR4pSi(OR5)q.

MATERIAL FOR ORGANIC ELECTRO-OPTICAL DEVICE HAVING FLUORENE DERIVATIVE COMPOUND AND ORGANIC ELECTRO-OPTICAL DEVICE INCLUDING THE SAME

The present invention relates to a material for an organic electro-optical device and an organic electro-optical device including the same. More particularly, the present invention relates to a material having thermal stability of a glass transition temperature of 120° C. or more and a thermal decomposition temperature of 450° C. or more, and being capable of providing an organic electro-optical device having high efficiency and a long life-span due to less crystallization and improved amorphous properties in a material for an organic electro-optical device. The material for an organic electro-optical device can be used singularly or as a host material in combination with a dopant, and includes an asymmetric fluorene derivative compound. An organic electro-optical device including the material for an organic electro-optical device is also provided.

PROCESS OF MAKING ALUMINUM ALKYLS

The present invention generally relates to a new process of making a trialkyl aluminum compound in which at least one alkyl group is a primary alkyl derived from an internal olefin or alpha-olefin. The process employs an isomerization/hydroalumination catalyst.

Reactivity of individual organolithium aggregates: A RINMR study of n-butyllithium and 2-methoxy-6-(methoxymethyl)phenyllithium

Low-temperature rapid injection NMR (RINMR) experiments were performed on two lithium reagents, n-butyllithium and 2-methoxy-6-(methoxymethyl)phenyllithium (5), with the goal of measuring the relative reactivity of the different aggregates (dimer, mixed dimer, and tetramer for n-BuLi, monomer and tetramer for 5) toward typical electrophiles. The reaction of the n-BuLi dimer with (trimethylsilyl)acetylene first forms the mixed dimer n-BuLi·Me3SiC≡CLi, which is about 1/60 as reactive as the n-BuLi homodimer. The tetramer does not react. In the deprotonation of (phenylthio)acetylene, the n-BuLi dimer was found to be 3.5 × 108 as reactive as the tetramer, and in the addition to p-diethylaminobenzaldehyde, the relative reactivity was at least 2 × 104. In the deprotonation of (p-tolylsulfonyl)acetylene, the monomer of 5 was at least 1014 times as reactive as the tetramer. These measurements show that the difference in reactivity between the lower and higher aggregates of organolithium reagents can be many orders of magnitude higher than all previous estimates. Copyright

Use of sulfur containing initiators for anionic polymerization of monomers

An initiator is presented for anionically polymerizing monomers, to provide a functional head group on the polymer. A polymer having a functional head group derived from a sulfur containing anionic initiator, and optionally as additional functional group resulting from the use of a functional terminating reagent, coupling agent or linking agent is also provided. A method is presented for anionically polymerizing monomers comprising the step of polymerizing the monomers with a sulfur containing anionic initiator to provide a functional head group on the polymer. An elastomeric compound, comprising a functional polymer and filler is also described. Also provided is a tire having decreased rolling resistance resulting from a tire component containing a vulcanizable elastomeric compound.

METHOD FOR PRODUCING ALKYL LITHIUM COMPOUNDS AND ARYL LITHIUM COMPOUNDS BY MONITORING THE REACTION BY MEANS OF IR-SPECTROSCOPY

The invention relates to a method for producing alkyl lithium compounds and aryl lithium compounds by reacting lithium metal with alkyl or aryl halogenides in a solvent, the concentration of the alkyl/aryl halogenide and the alkyl/aryl lithium compound being detected according to an in-line measurement in the reactor by means of IR spectroscopy, and an exact recognition of the end point of the dosing of the halogenide constituents being carried out by evaluation of the IR measurement. Said method enables an optimum reactive process and reaction yield. The identification of the respective concentration of the educt and the product is a reliable reactive process. The yield of the reaction is also optimised by determining the end point of the halogenide dosing, as is the purity of the product due to a lower concentration thereof during the reaction.

Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme: