30090-97-2

Basic information

• Product Name: Methanone, (4-methoxy-3-methylphenyl)phenyl-
• Synonyms: 4-methoxy-3-methylbenzophenone;4-benzoyl-2-methylanisole;3'-methyl-4'-methoxybenzophenone
• CAS NO: 30090-97-2
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Mol File: 30090-97-2.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Methanone, (4-methoxy-3-methylphenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methoxy-3-methylphenyl)phenyl-(30090-97-2)
• EPA Substance Registry System: Methanone, (4-methoxy-3-methylphenyl)phenyl-(30090-97-2)

Safety Data

• Hazardous Substances Data: 30090-97-2(Hazardous Substances Data)

Upstream product

• 578-58-5 2-methylmethoxybenzene 
• 2078-12-8 trimethylsilyl benzoate 
• 65-85-0 benzoic acid 
• 31040-84-3 4-tert-butyl-2-methylanisole 
• 98-88-4 benzoyl chloride 
• 93-97-0 benzoic acid anhydride 
• 611-94-9 4-Methoxybenzophenone 
• 5158-46-3 methylzinc chloride 
• 17637-11-5 2,3-bis-benzoyloxy-succinic acid anhydride 
• 65582-59-4 dimethyl 2-(benzoyloxy)succinate 
• 6304-99-0 dimethyl 2,3-bis(benzoyloxy)succinate 
• 14804-31-0 2-methyl-4-bromoanisole 
• 74-88-4 methyl iodide 

Downstream Products

• 861096-18-6 Hydroxy-diphenyl-(4-methoxy-3-methyl-phenyl)-methan 
• 412018-25-8 (+/-)-Hydroxy-phenyl-(4-methoxy-3-methyl-phenyl)-(naphthyl-⁽¹⁾)-methan 
• 108552-35-8 3-Bromomethyl-4-methoxybenzophenone 
• 5326-42-1 3-methyl-4-hydroxybenzophenone 
• 103158-41-4 2-methyl-4-trityl-anisole 
• 854749-99-8 4-(α-bromo-benzhydryl)-2-methyl-anisole 
• 409320-38-3 4-(chloro-[1]naphthyl-phenyl-methyl)-2-methyl-anisole 
• 409320-33-8 2-methyl-4-([1]naphthyl-phenyl-methylene)-cyclohexa-2,5-dienone 
• 804499-51-2 (4-methoxy-3-methyl-phenyl)-phenyl-methanol 

Relevant articles and documents

Selective Methylation of Arenes: A Radical C?H Functionalization/Cross-Coupling Sequence

A selective, nonchelation-assisted methylation of arenes has been developed. The overall transformation, which combines a C?H functionalization reaction with a nickel-catalyzed cross-coupling, offers rapid access to methylated arenes with high para selectivity. The reaction is amenable to late-stage methylation of small-molecule pharmaceuticals.

Syntheses, structures, and catalytic activity in Friedel–Crafts acylations of substituted tetramethylcyclopentadienyl molybdenum carbonyl complexes

Reactions of the substituted tetramethylcyclopentadienes [C5HMe4R] [R?=?tBu, Ph, CH2CH2C(CH3)3] with Mo(CO)3(CH3CN)3 in refluxing xylene gave a series of dinuclear molybdenum carbonyl complexes [(η5-C5Me4R)Mo(CO)3]2 [R?=?tBu (1), Ph (2), CH2CH2C(CH3)3 (3)], [(η5-C5MetBu)Mo(μ-CO)2]2 (4)], and [(η5-C5Me4)tBu]2Mo2O4(μ-O) (5)], respectively. Complexes 1–5 were characterized by elemental analysis, IR, 1H NMR, and 13C NMR spectroscopy. In addition, their crystal structures were determined by X-ray crystal diffraction analysis. The catalytic activities of complexes 1–3 in Friedel–Crafts acylation in the presence of o-chloranil has also been investigated; the reactions were achieved under mild conditions to give the corresponding products in moderate yields.

Friedel-crafts acylation reactions using esters

Intermolecular and intramolecular Friedel-Crafts acylation reactions of various aliphatic and aromatic esters at room temperature with the use of very simple reagents and activating groups in are described. The products were obtained in good yield (60-85 %). The detailed mechanistic pathway was studied by DFT calculations and supported by experimental evidence. Copyright