30354-91-7

Basic information

• Product Name: 2 4-DIAMINO-6-(4-METHOXYPHENYL)-1 3 5-
• Synonyms: 2,4-diamino-6-(4-methoxyphenyl)-s-triazine;5-triazine-2,4-diamine,6-(4-methoxyphenyl)-3;2 4-DIAMINO-6-(4-METHOXYPHENYL)-1 3 5-;1,3,5-Triazine-2,4-diaMine, 6-(4-Methoxyphenyl)-
• CAS NO: 30354-91-7
• Molecular Formula: C₁₀H₁₁N₅O
• Molecular Weight: 217.22724
• Product Categories: Heterocyclic Compounds;Building Blocks;Heterocyclic Building Blocks;Triazines
• Mol File: 30354-91-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 231-235 °C(lit.)
• Boiling Point: 518 °C at 760 mmHg
• Flash Point: 267.1 °C
• Appearance: /
• Density: 1.333 g/cm³
• Vapor Pressure: 7.77E-11mmHg at 25°C
• Refractive Index: 1.661
• PKA: 4.36±0.10(Predicted)
• CAS DataBase Reference: 2 4-DIAMINO-6-(4-METHOXYPHENYL)-1 3 5-(CAS DataBase Reference)
• NIST Chemistry Reference: 2 4-DIAMINO-6-(4-METHOXYPHENYL)-1 3 5-(30354-91-7)
• EPA Substance Registry System: 2 4-DIAMINO-6-(4-METHOXYPHENYL)-1 3 5-(30354-91-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• RTECS: WY0775054
• Hazardous Substances Data: 30354-91-7(Hazardous Substances Data)

Usage

General Description

2, 4-DIAMINO-6-(4-METHOXYPHENYL)-1, 3, 5-triazine is a chemical compound that belongs to the triazine class. It has the molecular formula C10H11N5O and a molecular weight of 213.23 g/mol. 2 4-DIAMINO-6-(4-METHOXYPHENYL)-1 3 5- is often used in the synthesis of heterocyclic compounds and pharmaceuticals. It is known for its potential application in the field of medicinal chemistry and drug development due to its diverse pharmacological activities. Additionally, it exhibits a variety of biological properties, making it a valuable compound for research and development in the pharmaceutical industry.

InChI:InChI=1/C10H11N5O/c1-16-7-4-2-6(3-5-7)8-13-9(11)15-10(12)14-8/h2-5H,1H3,(H4,11,12,13,14,15)

Upstream product

• 874-90-8 4-methoxybenzonitrile 
• 127099-85-8 N-Cyanoguanidine 
• 3397-62-4 2-Chloro-4,6-diamino-1,3,5-triazine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-94-9 4-methoxy-aniline 
• 1115-70-4 metformin hydrochloride 

Downstream Products

• 186834-94-6 N-[4-Isobutyrylamino-6-(4-methoxy-phenyl)-[1,3,5]triazin-2-yl]-isobutyramide 

Relevant articles and documents

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Synthesis, molecular docking studies, and in vitro evaluation of 1,3,5-triazine derivatives as promising antimicrobial agents

The six-membered ring heterocycle 1,3,5-triazine and its derivatives have attracted considerable attention as they have proven to be excellent bioactive herbicides, cancer agents, etc. A series of 1,3,5-triazine derivatives (3a-o) were synthesized by a single step reaction and characterized by 1H NMR, 13C NMR, and mass spectrometry analysis. Antimicrobial screening of title compounds (3a-o) was examined against five bacterial and two fungal strains. In vitro study revealed that the freshly synthesized 6-(thiazol-4-yl)-1,3,5-triazine-2,4-diamine (3o) showed good antibacterial growth inhibition against E. coli, K. pneumoniae, and A. baumannii bacterial strains, and even the fungi C. neoformans. Molecular docking studies were performed on the X-ray crystal structure of E. coli 24 kDa domain in complex with clorobiocin (PDB code: 1KZN; resolution 2.30 ?) using Surflex-Dock program of Sybyl-X software. The results obtained are very encouraging.

Microwave-assisted one-pot tandem reactions for direct conversion of primary alcohols and aldehydes to triazines and tetrazoles in aqueous media

(Chemical Equation Presented) A series of primary alcohols and aldehydes were treated with iodine in ammonia water under microwave irradiation to give the intermediate nitriles, which without isolation underwent [2 + 3] cycloadditions with dicyandiamide and sodium azide to afford high yields of the corresponding triazines and tetrazoles, including the α-amino- and dipeptidyl tetrazoles in high optical purity.