312307-38-3

Usage

Uses

Used in Pharmaceutical Industry:
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile is used as an impurity in the production of Vonoprazan, a P-CAB medication, for the treatment of gastric acid-related disorders. The presence of this impurity is crucial for quality control and safety assessments, as it can impact the efficacy and safety profile of the final drug product.
Used in Quality Control and Safety Assessments:
In the pharmaceutical industry, 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile serves as a reference compound for quality control and safety assessments of Vonoprazan. By monitoring the levels of this impurity, manufacturers can ensure that the final drug product meets the required standards for purity, efficacy, and safety.
Used in Research and Development:
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile may also be used in research and development for the study of P-CABs and their potential applications in treating gastric acid-related disorders. Understanding the properties and effects of this impurity can contribute to the development of new drugs or improvements in the synthesis and production processes of existing medications.

Upstream product

• 445-27-2 2'-Fluoroacetophenone 
• 109-77-3 malononitrile 

Downstream Products

• 1240948-81-5 S-{3-cyano-5-(2-fluorophenyl)-1H-pyrrol-2-yl}benzenecarbothioate 
• 2098974-13-9 1-[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrole-3-yl]-N-methylmethylamine fumaric acid salt 
• 881677-11-8 5‐(2-fluorophenyl)‐1‐(pyridine-3-sulfonyl)-1H-pyrrole-3-carbaldehyde 
• 881674-56-2 5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 
• 1240948-72-4 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile 
• 1240948-77-9 5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile 
• 1240949-27-2 4-(2-fluorophenyl)-2-(iminomethyl)-4-oxobutanenitrile 
• 1240948-83-7 2,2'-disulfanediylbis[5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile] 
• 881681-00-1 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-yl)-N-methylmethanamine 
• 1883595-39-8 C₁₇H₁₄FN₃O₃S 
• 1883595-37-6 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic acid 
• 1807642-39-2 5-(2-fluorophenyl)-1-(pyridin-3-yl-sulfonyl)-1H-pyrrole-3-carbonitrile 
• 2098974-13-9 (x)C₄H₄O₄*C₁₇H₁₆FN₃O₂S 

Relevant academic research and scientific papers

Synthesis method of 5-(2-fluorophenyl)-1H-pyrrole-3-formaldehyde

The invention discloses a synthetic method of 5-(2-fluorophenyl)-1H-pyrrole-3-formaldehyde, and belongs to the field of organic synthesis. The preparation method comprises the following steps: (1) reacting 2-fluoro acetophenone with a bromination reagent

Substituted pyrrole-4-alkylamine compounds and application thereof

The invention relates to substituted pyrrole-4-alkylamine compounds and application thereof. The invention particularly provides application of compounds shown in a formula I, or optical isomers thereof, or racemates thereof, or solvates thereof, or pharm

A fumaric acid fertile norah approves key intermediate and its preparation method (by machine translation)

The present invention provides a kind of fumaric acid fertile norah approves key intermediate and its preparation method. The invention fumaric acid fertile norah approves a key intermediate in the preparation method mainly comprises 3 step process, the p

Novel pyrroles derivative as well as preparation method and pharmaceutical application thereof

The invention relates to a novel pyrroles derivative as well as a preparation method and pharmaceutical application thereof. Specifically, the invention relates to the novel pyrroles derivative shown as a general formula (I) as well as pharmaceutically ac