31284-89-6Relevant articles and documents
Reductive Coupling of Carbon Dioxide and an Aldehyde Mediated by a Copper(I) Complex toward the Synthesis of α-Hydroxycarboxylic Acids
Masada, Koichiro,Kusumoto, Shuhei,Nozaki, Kyoko
supporting information, p. 4922 - 4926 (2020/04/21)
Copper-mediated reductive coupling between CO2 and an aldehyde to form α-hydroxycarboxylic acid was achieved using silylborane as a reductant. CO2 cleanly inserted into a copper-carbon bond that was formed by the reaction between a silylcopper-NHC complex
The Synthesis of Chiral α-Aryl α-Hydroxy Carboxylic Acids via RuPHOX-Ru Catalyzed Asymmetric Hydrogenation
Guo, Huan,Li, Jing,Liu, Delong,Zhang, Wanbin
, p. 3665 - 3673 (2017/09/11)
A ruthenocenyl phosphino-oxazoline-ruthenium complex (RuPHOX?Ru) catalyzed asymmetric hydrogenation of α-aryl keto acids has been successfully developed, affording the corresponding chiral α-aryl α-hydroxy carboxylic acids in high yields and with up to 97% ee. The reaction could be performed on a gram scale with a relatively low catalyst loading (up to 5000 S/C) and the resulting products can be transformed to several chiral building blocks, biologically active compounds and chiral drugs. (Figure presented.).
Silica sulfuric acid as a highly efficient catalyst for the synthesis of diarylacetic acids
Moore, Desiree L.,Denton, Allison E.,Kohinke, Rose M.,Craig, Brandon R.,Brenzovich, William E.
supporting information, p. 604 - 612 (2016/07/06)
ABSTRACT: An efficient heterogeneous method for the synthesis of diarylacetic acids was developed utilizing silica sulfuric acid as a catalyst. The reaction is highly efficient with a small amount of catalyst for the combination of a variety of electron-n
