313350-41-3

Basic information

• Product Name: 1H-Indole-3-carbonyl chloride, 1-(phenylmethyl)-
• CAS NO: 313350-41-3
• Molecular Formula: C16H12ClNO
• Molecular Weight: 269.73
• Mol File: 313350-41-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Indole-3-carbonyl chloride, 1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-carbonyl chloride, 1-(phenylmethyl)-(313350-41-3)
• EPA Substance Registry System: 1H-Indole-3-carbonyl chloride, 1-(phenylmethyl)-(313350-41-3)

Safety Data

• Hazardous Substances Data: 313350-41-3(Hazardous Substances Data)

Upstream product

• 27018-76-4 1-benzylindole-3-carboxylic acid 
• 10511-51-0 1-Benzylindole-3-carboxaldehyde 
• 487-89-8 Indole-3-carboxaldehyde 
• 771-50-6 1H-indole-3-carboxylic acid 
• 155134-26-2 1-Benzyl-1H-indole-3-carboxylic acid methyl ester 
• 942-24-5 3-methoxycarbonylindole 
• 100-39-0 benzyl bromide 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 877378-90-0 1-benzyl-N-[2-(6-methoxy-2-naphthyl)-2-oxoethyl]-1H-indole-3-carboxamide 
• 1003598-16-0 C₂₃H₁₈N₂O 
• 860611-46-7 N-methyl-1-benzylindole-3-carboxamide 
• 1093757-06-2 N-n-butyl-1-benzylindole-3-carboxamide 
• 1093757-05-1 N-ethyl-1-benzylindole-3-carboxamide 
• 1016011-15-6 N-n-propyl-1-benzylindole-3-carboxamide 
• 848853-53-2 1-benzyl-N-[(3'-bromo-4'-methoxy-1,1'-biphenyl-4-yl)methyl]-N-methyl-1H-indole-3-carboxamide 

Relevant articles and documents

Pd(II)-Catalyzed asymmetric oxidative annulation of N-alkoxyheteroaryl amides and 1,3-dienes

The first Pd(II)-catalyzed asymmetric oxidative annulation of N-alkoxyaryl amides and 1,3-dienes is reported, which features particular applicability for quick assembly of different types of chiral heterocycles with high yields and enantioselectivities. A novel chiral pyridine-oxazoline bearing a methoxyl group at the C-5 position and a gem-dimethyl group on the oxazoline moiety was found to be crucial for conversion.

Construction of indoloquinolinones via Pd(II)-catalyzed tandem CC/CN bond formation: Application to the total synthesis of isocryptolepine

Construction of indoloquinolinone skeleton via Pd-catalyzed tandem CC/CN bond formation has been achieved in moderate to good yields. The method was applied toward the total synthesis of the bioactive natural product isocryptolepine in good overall yields.

OXAZOLO-NAPHTHYL ACIDS AS PLAMINOGEN ACTIVATOR INHIBTOR TYPE-1 (PAI-1) MODULATORS USEFUL IN THE TREATMENT OF THROMBOSIS AND CARDIOVASCULAR DISEASES

The present invention relates to oxazolo-naphthyl acids of the formula (I) and methods of using them to modulate PAI-1 expression and to treat PAI-1 related disorders.