32366-25-9

Basic information

• Product Name: 1-Azidoethylbenzene
• Synonyms: (1-Azidoethyl)benzene;1-Azidoethylbenzene;1-Phenylethyl azide
• CAS NO: 32366-25-9
• Molecular Formula: C₈H₉N₃
• Molecular Weight: 148.1846
• Mol File: 32366-25-9.mol
• Article Data: 63

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 1-Azidoethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Azidoethylbenzene(32366-25-9)
• EPA Substance Registry System: 1-Azidoethylbenzene(32366-25-9)

Safety Data

• Hazardous Substances Data: 32366-25-9(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Odor

Sweet, floral

Uses

a. Chemical intermediate in the production of pharmaceuticals
b. Chemical intermediate in the production of dyes
c. Chemical intermediate in the production of other organic compounds
d. Potential precursor for the synthesis of azido-containing polymers and materials
e. Reagent in organic synthesis

Hazardous properties

Explosive

Safety precautions

Handle with caution due to explosive properties

InChI:InChI=1/C8H10N3/c1-7(10-11-9)8-5-3-2-4-6-8/h2-7,9H,1H3/q+1

Upstream product

• 100-41-4 ethylbenzene 
• 585-71-7 (1-bromoethyl)benzne 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 93-92-5 1-phenylethyl acetate 
• 4648-54-8 trimethylsilylazide 
• 100-42-5 styrene 
• 94073-86-6 (1-methoxymethoxy)ethylbenzene 
• 10604-60-1 (1-iodoethyl)benzene 
• 1524-12-5 1-phenylethyl 2,2,2-trifluoroacetate 
• 252031-74-6 tert-butyl 1-phenylethyl carbonate 
• 1445-91-6 (S)-1-phenylethanol 
• 98-86-2 acetophenone 
• 2040-37-1 benzyl 1-phenylethyl ether 
• 4013-34-7 3-phenyl-2-oxabutane 

Downstream Products

• 147169-48-0 (R,S)-N-(tert-butyloxycarbonyl)-α-methylbenzylamine 
• 618-36-0 rac-methylbenzylamine 
• 63778-17-6 1-(1-phenylethyl)-1H-1,2,3-triazole 
• 1259931-56-0 1-(1-phenyethyl)-1H-1,2,3-triazole-4,5-D₂ 
• 77473-29-1 1,2-dimethoxy-4-(1-phenylethyl)benzene 
• 779-54-4 phenyl(1-phenylethyl)amine 
• 30432-65-6 N-ethyl-N-(α-methylbenzyl)aniline 
• 103-69-5 N-ethyl-N-phenylamine 
• 100-47-0 benzonitrile 
• 98-86-2 acetophenone 
• 1277091-27-6 4-cyclopropyl-1-(1-phenylethyl)-1H-[1,2,3]triazole 
• 57957-24-1 N-(1-phenylvinyl)acetamide 
• 857489-17-9 N-(1-phenylethenyl)benzamide 
• 697301-70-5 tert-butyl 1-phenylvinylcarbamate 

Relevant articles and documents

Metal-Free Fast Azidation by Using Tetrabutylammonium Azide: Effective Synthesis of Alkyl Azides and Well-Defined Azido-End Polymethacrylates

An effective method to synthesize azido-end polymethacrylates from tetrabutylammonium azide (BNN3) in a nonpolar solvent (toluene) was developed. Several low-mass alkyl halides were reacted with BNN3 in toluene as model reactions and

Two-Step Protocol for Iodotrimethylsilane-Mediated Deoxy-Functionalization of Alcohols

We have developed a two-step protocol for iodotrimethylsilane-mediated deoxy-functionalization of primary and secondary alcohols to afford products containing a C?N, C?S, or C?O bond. In the first step the alcohol undergoes iodination with iodotrimethylsilane, and in the second, the iodine atom is replaced by a N, S, or O nucleophile. Compared with traditional Mitsunobu reaction, non-acidic pre-nucleophiles can be used, and the reaction proceeds with retention of configuration. This operationally simple, highly efficient protocol can be used for some natural products and small-molecule drugs containing hydroxy-group.

Direct AlCl3-catalyzed transformation of benzyl THP ethers and allyl benzyl ethers

THP and allyl groups are frequently used for the protection of alcohols. In this study, novel direct transformations of benzyl THP ethers and allyl benzyl ethers, protected forms of alcohols, are reported. TMSN3 and AlCl3 were employ