10604-60-1

Usage

Uses

Used in Organic Synthesis:
1-Iodo-1-phenylethane is used as a reagent in organic synthesis for the formation of carbon-carbon bonds. Its ability to participate in various organic reactions makes it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1-iodo-1-phenylethane is used as a precursor for the synthesis of important chemicals. Its role in creating the building blocks of various medications highlights its significance in drug development.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical sector, benzyl iodide is employed as a precursor in the synthesis of essential chemicals. This application underscores its importance in the development of agricultural products, such as pesticides and fertilizers, which contribute to enhanced crop protection and yield.

InChI:InChI=1/C8H9I/c1-7(9)8-5-3-2-4-6-8/h2-7H,1H3

Upstream product

• 98-85-1 1-Phenylethanol 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 100-42-5 styrene 
• 1517-69-7 (R)-1-phenylethanol 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 100-41-4 ethylbenzene 
• 98-88-4 benzoyl chloride 
• 4659-45-4 2,6-Dichlorobenzoyl chloride 
• 94073-86-6 (1-methoxymethoxy)ethylbenzene 
• 31600-55-2 benzyl methoxymethyl ether 
• 34881-06-6 (+/-)-1-phenylethyl diethyl phosphate 
• 93-96-9 bis(1-phenylethyl)ether 
• 672-65-1 (1-chloroethyl)benzene 
• 105966-39-0 2-(1-phenylethoxy)-tetrahydro-2H-pyran 

Downstream Products

• 146040-13-3 3,4-Bis-(1-phenyl-ethyl)-cyclobut-3-ene-1,2-dione 
• 7214-65-5 α-phenethyl nitrate 
• 100-42-5 styrene 
• 492-37-5 hydratropic acid 
• 98-86-2 acetophenone 
• 53759-17-4 α-methylbenzyl trimethyl ammonium iodide 
• 4613-11-0 2,3-diphenylbutane 
• 2726-21-8 2,3-diphenylbutane 
• 32366-25-9 1-azidoethylbenzene 
• 4809-56-7 N-(1-phenylethyl)-p-toluenesulfonamide 
• 10340-49-5 4-phenyl-1-pentene 
• 1100569-50-3 C₁₄H₁₅NO₂ 
• 70096-24-1 (η5-C5H5)Fe(CO)(CN)(α-phenylethyl isocyanide) 

Relevant academic research and scientific papers

A mild and highly chemoselective iodination of alcohol using polymer supported DMAP

The synthesis of organic compounds using polymer supported catalysts and reagents, where the required product is always in solution, has been of great interest in recent years, both in industries and academia especially in pharmaceutical research. Here, a simple and efficient method for conversion of alcohols into their iodides in high yield using polymer supported 4-(Dimethylamino)pyridine (DMAP) is described. Polymer supported DMAP is used in catalytic amount and is recovered and reused several times. Additionally, this method is highly chemoselective. [Figure not available: see fulltext.]

Iodination of alcohols using triphenylphosphine/iodine under solvent-free conditions using microwave irradiation

A straightforward and effective procedure for the conversion of benzylic, allylic and aliphatic alcohols to the corresponding iodides using Ph3P/I2 under solvent-free conditions using microwave irradiation is reported.

Vapor pressures and enthalpies of vaporization of benzyl halides and benzyl ethers

Molar enthalpies of vaporization ΔlgHmo of seven benzyl halides and seven benzyl ethers have been obtained from the temperature dependence of the vapor pressure measured by the transpiration method. These values and the correlation-gas chromatography method, based on Kovat's index, have been applied for the determination of ΔlgHmo of three cumyl halides (Cl, Br, and I). The data obtained for ΔlgHmo of benzyl derivatives have been checked successfully for internal consistency using enthalpies of formation of alkyl halides and alkyl ethers available from the literature.

Silica chloride in the presence of NaI is a useful system for the efficient and selective conversion of TMS, TBDMS and THP ethers into their corresponding iodides

Direct and highly selective conversion of benzylic, allylic and propargylic TMS, TBDMS and THP ethers into their corresponding iodides with the SiO2-Cl/NaI system is described. Reactions were conducted in CH3CN at room temperature. Aliphatic silyl and tetrahydropyranyl ethers remained almost intact under similar reaction conditions.

Efficient method for iodination of alcohols using KI/silica sulfuric acid (SSA)

A straightforward and effective procedure for the conversion of benzylic and allylic alcohols to the corresponding iodides using KI/SSA in acetonitrile at room temperature. Copyright Taylor & Francis Group, LLC.

An expedient stereoselective synthesis of (Z)- and (E)-allyl iodides from Baylis-Hillman adducts along with selective iodination of benzylic alcohols using the polymethylhydrosiloxane-iodine system

A stereoselective method has been developed for the synthesis of (Z)- and (E)-allyl iodides from Baylis-Hillman adducts using polymethylhydrosiloxane (PMHS) and iodine in chloroform at room temperature. In addition, the reagent system has been utilized for the iodination of benzylic alcohols selectively.

Facile preparation of benzylic iodides under solvent-free conditions using microwave irradiation

Benzylic alcohols are rapidly converted to the corresponding benzylic iodides using combination of p-toluenesulfonic acid (PTSA) and potassium iodide under solvent-free microwave irradiation conditions.

Direct Conversion of Alcohols into the Corresponding Iodides

A mild and effective procedure for directly converting secondary, tertiary and benzylic alcohols into the corresponding iodides is described using I2 in refluxing petroleum ether.The reaction proceeds with inversion of configuration.

An efficient and facile hydroiodination of alkenes and alkynes PI using polymethylhydrosiloxane-iodine system

A mild and efficient method has been developed for the synthesis of alkyl and alkenyl iodides from alkenes and alkynes using polymethylhydrosiloxane (PMHS) and iodine in chloroform at room temperature. The reagent system generates hydrogen iodide which regioselectively adds to the alkenes and alkynes. Copyright

Convenient and efficient method for the iodination of benzylic and aliphatic alcohols by using Al(HSO4)3/KI in nonaqueous solution

A simple and efficient method for the iodination of benzylic and aliphatic alcohols by using Al(HSO4)3/KI in n-hexane as solvent is reported. Mild reaction conditions and good to excellent yields of the products are the noteworthy advantages of the method. Copyright Taylor & Francis LLC.