32770-97-1Relevant academic research and scientific papers
GLYCOSIDASE INHIBITORS
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, (2016/03/22)
Compounds of formula (I) wherein A, R, W, Q, n and m have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS
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, (2015/11/25)
In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.
Total synthesis and antitumor activity of ZK-EPO: The first fully synthetic epothilone in clinical development
Klar, Ulrich,Buchmann, Bernd,Schwede, Wolfgang,Skuballa, Werner,Hoffmann, Jens,Lichtner, Rosemarie B.
, p. 7942 - 7948 (2007/10/03)
Going to trial: From about 350 active epothilone analogues synthesized by a highly convergent synthesis, one (ZK-EPO, see picture) has been chosen for clinical development on the basis of its outstanding preclinical data. This compound exhibits higher activity and efficacy than taxanes (e.g. paclitaxel) and second-generation epothilones, a fast and efficient cellular uptake, no recognition by efflux mechanisms, and an improved therapeutic window. (Chemical Equation Presented)
Synthesis of a new spiropyran based on [60]fullerene unit
Xu, Ju-Hua,Li, Yu-Liang,Zhu, Dao-Ben
, p. 1647 - 1652 (2007/10/03)
A new compound 2: spiropyran with [60]fullerene unit was synthesized and characterized by FT-IR, MALDI-TOF MS, NMR, and UV-Vis spectra.
