33525-72-3

Basic information

• Product Name: 2-(1-butylamino)pyridine
• Synonyms: 2-(1-butylamino)pyridine
• CAS NO: 33525-72-3
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 150
• Mol File: 33525-72-3.mol
• Article Data: 25

Chemical Properties

• Melting Point: 42 °C
• Boiling Point: 116 °C(Press: 10 Torr)
• Appearance: /
• Density: 0.990±0.06 g/cm3(Predicted)
• PKA: 6.72±0.10(Predicted)
• CAS DataBase Reference: 2-(1-butylamino)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-butylamino)pyridine(33525-72-3)
• EPA Substance Registry System: 2-(1-butylamino)pyridine(33525-72-3)

Safety Data

• Hazardous Substances Data: 33525-72-3(Hazardous Substances Data)

Usage

Classification

Aromatic amine, Pyridine derivative

Usage

Building block in organic synthesis and pharmaceutical research

Potential

Medicinal and bioactive applications, drug development, treatments

Role

Ligand in coordination chemistry

Industrial applications

Structural versatility, reactivity

Unique features

Chemical properties, functional groups

Value

Component in the synthesis of diverse molecular structures with potential uses in various fields.

Upstream product

• 110-86-1 pyridine 
• 109-73-9 N-butylamine 
• 109-09-1 2-chloropyridine 
• 109-65-9 1-bromo-butane 
• 40825-17-0 Natrium-Verbindung des [2]Pyridylamins 
• 778-28-9 butyl para-toluenesulfonate 
• 504-29-0 2-aminopyridine 
• 71-36-3 butan-1-ol 
• 5029-67-4 2-iodopyridine 
• 109-04-6 2-bromo-pyridine 
• 1541-40-8 2,3-dihydrothiazolo<3,2-a>pyridinium bromide 
• 107-92-6 butyric acid 
• 34813-97-3 2-(formylamino)pyridine 
• 13606-95-6 N-(pyridin-2-yl)butyramide 

Downstream Products

• 850724-07-1 3-{4-[2-(butyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester 
• 893429-18-0 3-{3-[2-(butyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid ethyl ester 
• 1100049-69-1 4-{4-[2-(n-butyl-2-pyridinylamino)ethoxy]phenyl}butyric acid methyl ester 
• 1176950-31-4 C₁₈H₁₈N₂O₂ 

Relevant articles and documents

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Pyridine mediated transition-metal-free direct alkylation of anilines using alcohols: via borrowing hydrogen conditions

Herein, we report pyridine and other similar azaaromatics as efficient biomimetic hydrogen shuttles for a transition-metal-free direct N-alkylation of aryl and heteroaryl amines using a variety of benzylic and straight chain alcohols. Mechanistic studies including deuterium labeling and the isolation of dihydro-intermediates of the benzannulated pyridine confirmed the role of pyridine and a borrowing hydrogen process operating in these reactions. In addition, we have extended this methodology for the development of dehydrogenative synthesis of quinolines and indoles, as well as the transfer hydrogenation of ketones. This journal is

Mesoionic pyrido[1,2-a]pyrimidinones: A novel class of insecticides inhibiting nicotinic acetylcholine receptors

A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species, particularly hemiptera and lepidoptera. Mode-of-action studies showed that they act on nicotinic acetylcholine receptors (nAChRs) primarily as inhibitors. Here we report the discovery, evolution, and preparation of this class of chemistry. Our efforts in structure–activity relationship elucidation and biological activity evaluation are also presented.