3360-53-0

Usage

Appearance

Colorless to yellow liquid The compound's appearance ranges from colorless to yellow in its liquid state.

Strong, pungent odor

1-Bromo-2-phenylpropene has a noticeable and pungent smell.

Primary use

Intermediate in synthesis The compound is mainly used as an intermediate in the production of pharmaceuticals and agrochemicals.

Additional uses

Reagent in organic synthesis, building block in specialty chemicals It also serves as a reagent in organic synthesis and as a building block for creating specialty chemicals.

Flammability

Flammable 1-Bromo-2-phenylpropene is considered to be flammable, which requires caution during handling and storage.

Upstream product

• 704-80-3 (E)-3-phenyl-2-butenoic acid 
• 31778-29-7 1-bromo-2-phenylpropan-2-ol 
• 1034-49-7 (bromomethyl)triphenyl phosphonium bromide 
• 98-86-2 acetophenone 
• 98-83-9 isopropenylbenzene 
• 100-52-7 benzaldehyde 
• 60014-86-0 (2,2-dibromo 1-methylethenyl)benzene 
• 704-79-0 3-phenylbut-2-enoic acid 
• 60014-81-5 1,2-dibromo-2-trimethylsilyloxy-prop-2-yl-benzene 

Downstream Products

• 833-81-8 1,2-diphenylpropene 
• 16819-47-9 2,5-diphenylhexa-2,4-diene 
• 40962-69-4 diethyl 2-phenyl-2-methylvinylphosphonate 
• 98-86-2 acetophenone 
• 3360-55-2 β-chloro-α-methylstyrene 
• 673-32-5 1-Phenylprop-1-yne 
• 6054-00-8 3-phenyl-2H-benzopyran 
• 88040-01-1 6-chloro-3-phenyl-2H-benzopyran 
• 88039-97-8 6-Methoxy-3-phenyl-2H-chromene 
• 112635-45-7 C₁₅H₁₃BrO 
• 112635-57-1 6-Methyl-3-phenyl-2H-chromene 
• 112635-47-9 1-((E)-3-Bromo-2-phenyl-allyloxy)-4-methyl-benzene 
• 112635-49-1 1-((E)-3-Bromo-2-phenyl-allyloxy)-4-chloro-benzene 
• 112635-58-2 6,8-Dichloro-3-phenyl-2H-chromene 

Relevant academic research and scientific papers

Highly selective hydrosilylation of equilibrating allylic azides

The Pt-catalyzed hydrosilylation of equilibrating allylic azides is reported. The reaction provides only one out of four possible hydrosilylation products in good yields and with very high chemoselectivity (alk-1-enevs.alk-2-ene), regioselectivity (linearvs.branched), and excellent functional group tolerance.

Nickel-Catalyzed Reductive Cross-Coupling of Vinyl Bromides with Unactivated Alkyl Halides

The use of pyridine as the sole ligand for the reductive vinylation of unactivated secondary alkyl halides under Ni-catalyzed conditions has been developed. Both alkyl- and aryl-substituted vinyl bromides are suitable, in which alkyl-decorated α-alkenyl bromides resulted in the α-products in good results.

Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactions

Intramolecular [2+2] photocycloaddition reactions of diversely substituted N-Boc protected 4-(allylaminomethyl)-2(5H)-furanones resulted in rigid products (53-75%) with three spatially defined positions for further functionalisation. The Royal Society of Chemistry.

Syntheses of strychnine, norfluorocurarine, dehydrodesacetylretuline, and valparicine enabled by intramolecular cycloadditions of Zincke aldehydes

A full account of the development of the base-mediated intramolecular Diels-Alder cycloadditions of tryptamine-derived Zincke aldehydes is described. This important complexity-generating transformation provides the tetracyclic core of many indole monoterpene alkaloids in only three steps from commercially available starting materials and played a key role in short syntheses of norfluorocurarine (five steps), dehydrodesacetylretuline (six steps), valparicine (seven steps), and strychnine (six steps). Reasonable mechanistic possibilities for this reaction, a surprisingly facile dimerization of the products, and an unexpected cycloreversion to regenerate Zincke aldehydes under specific conditions are also discussed.

NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS

Photoinitiators of formula (Ia) or (Ib) having chain transfer groups, wherein n is 1 or 2; PI is for example a group of formula (IIa); PI' inter alia is a group of formula (IIIa); Ar is for example phenyl; Ar2 is inter alia phenylene; R1 and R2 are for ex

New synthesis of vaulted biaryl ligands via the Snieckus phenol synthesis

(Chemical Equation Presented) In an effort to develop a synthesis of the VAPOL ligand that avoids the use of a chromium carbene complex, a route was examined that involved the annulation of a naphthalene carboxamide via the method of Snieckus. The latter

Formation of nanoarchitectures including subnanometer palladium clusters and their use as highly active catalysts

Subnanometer Pd clusters stabilized within micelles of random copolymers were formed by direct immobilization of Pd(0) via ligand exchange. The clusters were estimated to contain approximately seven Pd atoms on average (cluster diameter ≈ 0.7 nm). Several

Polymer-micelle incarcerated ruthenium catalysts for oxidation of alcohols and sulfides

Highly active immobilized ruthenium catalysts, which can be used for oxidation of alcohols and sulfides, were developed on the basis of the polymer-micelle incarcerated (PMI) method. The catalysts could be recovered and reused several times without loss of activity and no metal leaching was observed. Selection of micelle-forming conditions and polymer structures were key in achieving high activities. TEM and SEM analyses were conducted to observe the structures of PMI-Ru.

CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine protease, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceut

A stable β-silyl carbocation with allyl conjugation

Phenyl group replaced by a double bond yielding a stable β-silyl carbocation was studied. Two systems were examined in which positive charge could be stabilized by one phenyl and one double bond or two double bonds. The carbocation was found to be stable at room temperature with tetrakis(pentafluorophenyl)borate as the anion benzene as the solvents. The range of β-silyl carbocations observed under stable ion conditions was relatively circumscribed.