3362-33-2

Basic information

• Product Name: {[(diphenylmethylidene)amino]oxy}(phenyl)methanone
• Synonyms: methanone, [[(diphenylmethylene)amino]oxy]phenyl-
• CAS NO: 3362-33-2
• Molecular Formula: C₂₀H₁₅NO₂
• Molecular Weight: 301.3386
• Mol File: 3362-33-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 442°C at 760 mmHg
• Flash Point: 184°C
• Density: 1.08g/cm³
• Vapor Pressure: 5.18E-08mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: {[(diphenylmethylidene)amino]oxy}(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: {[(diphenylmethylidene)amino]oxy}(phenyl)methanone(3362-33-2)
• EPA Substance Registry System: {[(diphenylmethylidene)amino]oxy}(phenyl)methanone(3362-33-2)

Safety Data

• Hazardous Substances Data: 3362-33-2(Hazardous Substances Data)

Usage

General Description

The chemical {[(diphenylmethylidene)amino]oxy}(phenyl)methanone, also known as benzophenone imine, is an organic compound with the molecular formula C19H13NO2. It is a white to off-white solid that is insoluble in water but soluble in organic solvents. {[(diphenylmethylidene)amino]oxy}(phenyl)methanone is often used as a reagent in organic synthesis, particularly in the formation of carbon-carbon bonds. It can also be used as a photoinitiator in the production of photopolymers and as a synthetic intermediate in pharmaceuticals and agrochemicals. However, it is important to handle benzophenone imine with caution, as it may be harmful if ingested or inhaled and can cause irritation to the skin and eyes.

Upstream product

• 119-61-9 benzophenone 
• 574-66-3 Benzophenone oxime 
• 65-85-0 benzoic acid 
• 1485-71-8 benzophenone oxime 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1008-88-4 3-phenylpyridine 
• 1008-89-5 2-phenylpyridine 
• 939-23-1 p-phenylpyridine 
• 119-61-9 benzophenone 
• 92-52-4 biphenyl 
• 983-79-9 benzophenone azine 
• 93-98-1 N-phenyl benzoyl amide 
• 100-47-0 benzonitrile 
• 65-85-0 benzoic acid 
• 133469-21-3 N-benzhydryl-1-phenylethan-1-amine 
• 70591-20-7 N-(diphenylmethylene)aminoacetonitrile 
• 67174-42-9 N-(1-ethoxyethyl)-1,1-diphenylmethanimine 
• 83196-02-5 2-<(Diphenylmethylidene)amino>cyclohexanone 
• 7699-79-8 benzhydrylidene-benzyl-amine 

Relevant articles and documents

Direct C(sp3)-N Radical Coupling: Photocatalytic C-H Functionalization by Unconventional Intermolecular Hydrogen Atom Transfer to Aryl Radical

An unconventional approach for intermolecular direct C(sp3)-N radical coupling has been developed by photocatalytic C(sp3)-H activation of simple alkyl substrates using O-benzoyl oximes. The selective photocatalytic energy-transfer-driven homolysis followed by decarboxylation generates the persistent iminyl radical and aryl radical, which would undergo an unprecedented intermolecular hydrogen atom abstraction from the alkyl substrate to provide the key C(sp3) radical. Selective radical-radical C-N cross-coupling furnishes imines which are valuable amine building blocks.

A convenient practical synthesis of alkyl and aryl oxime esters

A facile access to the synthesis of alkyl and aryl oxime esters of ketoximes and aldoximes in high yields (90-97%) is reported. The reactions were performed using N-[3-(methylamino)propyl]-N′-ethylcarbodiimide hydrochloride (EDCI) reagent in the presence of 4-(dimethylamino)pyridine (DMAP) as a catalyst at room temperature. The isolation and purification of products is very simple and in cases where product is solid, column chromatography is avoided. Georg Thieme Verlag Stuttgart New York.

(E)-Phenyl- and -heteroaryl-substituted O-benzoyl-(or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitors

A series of (E)-phenyl- and -heteroaryl-substituted O-benzoyl- (or acyl)oximes 3a-n were synthesized for evaluating their human lipoprotein-associated phospholiphase A2 (Lp-PLA2) inhibitory activities. The less lipophilic derivatives 3a-c showed the most potent in vitro inhibitory activity on human Lp-PLA2.