34025-29-1

Basic information

• Product Name: 2-hydroxy-2-phenyl-acetaldehyde
• Synonyms: 2-hydroxy-2-phenyl-acetaldehyde
• CAS NO: 34025-29-1
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 136.15
• Mol File: 34025-29-1.mol
• Article Data: 23

Chemical Properties

• Melting Point: 135-138 °C
• Boiling Point: 237.3°Cat760mmHg
• Flash Point: 96.8°C
• Appearance: /
• Density: 1.155g/cm³
• Vapor Pressure: 0.0247mmHg at 25°C
• Refractive Index: 1.549
• PKA: 12.53±0.20(Predicted)
• CAS DataBase Reference: 2-hydroxy-2-phenyl-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-2-phenyl-acetaldehyde(34025-29-1)
• EPA Substance Registry System: 2-hydroxy-2-phenyl-acetaldehyde(34025-29-1)

Safety Data

• Hazardous Substances Data: 34025-29-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8O2/c9-6-8(10)7-4-2-1-3-5-7/h1-6,8,10H

Upstream product

• 93-56-1 phenylethane 1,2-diol 
• 50-00-0 formaldehyd 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 23120-95-8 (4,5-dihydro-1H-imidazol-2-yl)-phenyl-methanol 
• 87682-28-8 Phenyl-trimethylsilanyloxy-acetaldehyde 
• 100520-05-6 2,2-bis(ethylthio)-1-phenylethanol 
• 21504-23-4 2,2-dimethoxy-1-(phenyl)ethanol 
• 21087-52-5 2-methoxy-3-phenyl-oxirane 
• 100-52-7 benzaldehyde 
• 100-42-5 styrene 
• 1169707-70-3 (S,Z)-1-phenylbut-2-ene-1,4-diol 
• 1074-12-0 phenylglyoxal hydrate 
• 109459-35-0 methyl (R)-2-phenyl-2-((trimethylsilyl)oxy)acetate 
• 20698-91-3 (R)-methyl mandelate 

Downstream Products

• 16761-08-3 phenylvinylene carbonate 
• 17199-29-0 (S)-Mandelic acid 
• 16355-00-3 (R)-1-phenyl-1,2-ethanediol 
• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 
• 875-74-1 (R)-phenylglycine 
• 2935-35-5 (S)-2-phenylglycine 
• 611-73-4 Benzoylformic acid 
• 611-71-2 MANDELIC ACID 
• 5021-43-2 2-phenylquinoxaline 
• 73166-13-9 2,4-diphenyl-morpholine 
• 90005-59-7 E/Z-mandelaldoxime 
• 611-71-2 (R)-Mandelic Acid 
• 78648-24-5 2,5-Bis-acetoxy-3,6-diphenyl-1,4-dioxan 
• 79224-27-4 2,3-dihydroxy-3-phenylpropanenitrile 

Relevant articles and documents

Carbanions with two N substituents: Nucleophilic acyl-group-transfer reagents

(Chemical Equation Presented) Without mercury or thallium: A new umpoled nucleophilic acylation reagent is formed in the direct deprotonation of 1,3,5-trimethyl-1,3,5-triazacyclohexane with butyllithium. The carbanionic center is flanked by two amino grou

Thiamine Diphosphate Dependent KdcA-Catalysed Formyl Elongation of Aldehydes

The formose reaction, one of the oldest name reactions in organic chemistry, uses formaldehyde as a C1 unit resulting in different monosaccharides and sugar-like compounds. Nucleophilic formyl elongation is an attractive option to obtain 1,2-fu

A simple primary amine catalyst for enantioselective α-hydroxylations and α-fluorinations of branched aldehydes

A new primary amine catalyst for the asymmetric α-hydroxylation and α-fluorination of α-branched aldehydes is described. The products of the title transformations are generated in excellent yields with high enantioselectivities. Both processes can be performed within short reaction times and on gram scale. The similarity in results obtained in both reactions, combined with computational evidence, implies a common basis for stereoinduction and the possibility of a general catalytic mechanism for α-functionalizations. Promising initial results in α-amination and α-chlorination reactions support this hypothesis.