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2-(Bromomethyl)-2-phenyl-1,3-dioxolane, a chemical compound with the molecular formula C9H9BrO2, is a colorless liquid characterized by a molecular weight of 227.08 g/mol. This versatile molecule features both a bromomethyl group and a phenyl group, which endows it with a wide range of chemical reactivity and potential applications across different industries.

3418-21-1

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3418-21-1 Usage

Uses

Used in Organic Synthesis:
2-(Bromomethyl)-2-phenyl-1,3-dioxolane is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, facilitating the creation of complex organic molecules.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane is utilized as a key intermediate in the synthesis of drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Production:
2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE also serves as a reagent in the production of agrochemicals, playing a role in the synthesis of pesticides and other agricultural chemicals to protect crops and enhance yields.
Used as a Crosslinking Agent in Polymer Production:
2-(Bromomethyl)-2-phenyl-1,3-dioxolane is employed as a crosslinking agent in polymer chemistry, enhancing the properties of polymers by creating a network structure that improves stability and durability.
Used as a Solvent in Chemical Processes:
Due to its solubility properties, 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE functions as a solvent in a variety of chemical processes, aiding in the dissolution of substances and facilitating reactions.
It is crucial to handle 2-(Bromomethyl)-2-phenyl-1,3-dioxolane with care, as it can cause skin and eye irritation and respiratory issues if inhaled, indicating the need for proper safety measures during its use.

Check Digit Verification of cas no

The CAS Registry Mumber 3418-21-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,1 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3418-21:
(6*3)+(5*4)+(4*1)+(3*8)+(2*2)+(1*1)=71
71 % 10 = 1
So 3418-21-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H11BrO2/c11-8-10(12-6-7-13-10)9-4-2-1-3-5-9/h1-5H,6-8H2

3418-21-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

1.2 Other means of identification

Product number -
Other names bromomethylphenyldioxolane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3418-21-1 SDS

3418-21-1Relevant articles and documents

Novel Dioxolane Ring Compounds for the Management of Phytopathogen Diseases as Ergosterol Biosynthesis Inhibitors: Synthesis, Biological Activities, and Molecular Docking

Min, Li-Jing,Wang, Han,Bajsa-Hirschel, Joanna,Yu, Chen-Sheng,Wang, Bin,Yao, Meng-Meng,Han, Liang,Cantrell, Charles L.,Duke, Stephen O.,Sun, Na-Bo,Liu, Xing-Hai

, p. 4303 - 4315 (2022/04/15)

Thirty novel dioxolane ring compounds were designed and synthesized. Their chemical structures were confirmed by 1H NMR, HRMS, and single crystal X-ray diffraction analysis. Bioassays indicated that these dioxolane ring derivatives exhibited ex

Propiconazole-like compound, and preparation method and application thereof

-

Paragraph 0023-0025, (2021/08/11)

The invention discloses a propiconazole-like compound, and a preparation method and application thereof. The structural formula of the propiconazole-like compound is represented by formula (I)shown in the specification. In the formula (I), X is H, bromine

Application of poly(vinylphenyltrimethylammonium tribromide) resin as an efficient polymeric brominating agent in the α-bromination and α-bromoacetalization of acetophenones

Han, Bingbing,Zheng, Zubiao,Zheng, Dongcheng,Zhang, Lei,Cui, Peng,Shi, Jianjun,Li, Changjiang

supporting information, p. 2512 - 2520 (2019/07/04)

The applications of a new supported tribromide reagent based on poly(vinylbenzyltrimethylammonium hydroxide) resin (Amberlite 717) were reported. This supported tribromide resin was used directly in α-bromination and α-bromoacetalization of acetophenones without any other catalyst under mild conditions. The effects of solvents and the amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of α-bromo and α-bromoacetal of acetophenones were selectively obtained in excellent yields.

One-pot synthesis of α-bromoacetals of ketones from secondary alcohols and 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) in ethylene glycol

Han, Bingbing,Zheng, Zubiao,Wu, Fang,Wang, Aidong

supporting information, p. 2387 - 2394 (2017/11/15)

α-Bromoacetals of ketones were prepared from various secondary alcohols with 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) and ethylene glycol through oxidation, bromination, and acetalization in one pot without the use of other catalysts under mild conditions. The effects of DBDMH, the solvent, and N-bromosuccinimide on the reaction were investigated. Under the optimal conditions, most α-bromoacetals of ketones were obtain in 90–98% yields.

One-step for the preparation of α-haloacetal of ketones with N-bromosuccinimide/N-chlorosuccinimide (NBS/NCS) and ethylene glycol

Zheng, Zubiao,Han, Bingbing,Wu, Fang,Shi, Tengfei,Liu, Jie,Zhang, Yong,Hao, Jialong

, p. 7738 - 7743 (2016/11/17)

A new process that could directly prepare α-haloacetal of ketones from various ketones with N-halosuccinimide (NBS/NCS) and ethylene glycol in one step without any other catalysts was reported. The effects of solvents, NBS/NCS and reaction temperature were investigated. Under the optimal condition, most of α-haloacetals of ketones were obtained in 90–100% yield.

Cyclopentyl methyl ether-NH4X: A novel solvent/catalyst system for low impact acetalization reactions

Azzena, Ugo,Carraro, Massimo,Mamuye, Ashenafi Damtew,Murgia, Irene,Pisano, Luisa,Zedde, Giuseppe

supporting information, p. 3281 - 3284 (2015/06/25)

Cyclopentyl methyl ether, a low impact ether forming a positive azeotrope with water, was successfully employed as a solvent in the synthesis of 1,3-dioxanes and 1,3-dioxolanes carried out under Dean-Stark conditions by the acetalization of aliphatic and aromatic aldehydes or ketones, employing ammonium salts as environmentally friendly acidic catalysts.

Synthesis, characterization, and structures of α-substituted selenenyl-acetophenones

Hodage, Ananda S.,Phadnis, Prasad P.,Wadawale, Amey,Priyadarsini,Jain, Vimal K.

supporting information, p. 700 - 710 (2014/06/09)

A series of α-substituted selenenyl acetophenone derivatives of the types, [PhC(OCH2CH2O)CH2Se]2, [PhC(OCH2CH2O)CH2SeR], (PhCOCH2Se) 2, and [PhCOCH2/s

An eco-friendly and efficient synthesis of benzoylformic acid and methyl benzoylformate from styrene

Dai, Zhihong,Peng, Xinhua,Dong, Xiongzi,Shi, Chunjie,Rong, Yuan

, p. 4979 - 4985 (2012/10/07)

The HBr/H2O2 system was found to be highly efficient and green catalytic system for the selective oxidation of styrene to benzoylformic acid in excellent yields under water as solvent. The process of etherification is simple, highly efficient and inexpensive by using TiO 2/ SO42- as catalyst.

Optimization of Grignard ring-opening of α-brominated dioxolanes for the preparation of β-hydroxy-protected vinyl ethers by a three-step one-pot procedure

André, Mathieu,Letribot, Boris,Bayle, Martine,Mounetou, Emmanuelle,Chezal, Jean-Michel

, p. 6107 - 6110 (2012/11/07)

Aliphatic, cyclic, and aromatic benzoate-protected γ-hydroxy enol ethers were prepared from α-brominated dioxolanes by a three-step reaction procedure and a one-pot protocol involving Grignard reagent formation, ring-opening, and final benzoate protection

Enantioselective synthesis of quinolizidines and indolizidines via a catalytic asymmetric hydrogenation cascade

Rueping, Magnus,Hubener, Lukas

supporting information; experimental part, p. 1243 - 1246 (2011/07/31)

A catalytic enantioselective synthesis of a new class of quinolizidines and indolizidines is presented. An asymmetric Bronsted acid catalyzed hydrogenation cascade as well as a sequential Bronsted acid/metal catalyzed hydrogenation protocol of 2-substituted quinolines yields benzofused quinolizidines and indolizidines in good yields with high diastereo- and enantioselectivities. Georg Thieme Verlag Stuttgart - New York.

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