3418-21-1

Basic information

• Product Name: 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE
• Synonyms: 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE
• CAS NO: 3418-21-1
• Molecular Formula: C₁₀H₁₁BrO₂
• Molecular Weight: 243.1
• Mol File: 3418-21-1.mol
• Article Data: 20

Chemical Properties

• Melting Point: 63-65°
• Boiling Point: 308.1°Cat760mmHg
• Flash Point: 130.5°C
• Appearance: /
• Density: 1.449g/cm³
• Vapor Pressure: 0.00127mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE(3418-21-1)
• EPA Substance Registry System: 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE(3418-21-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3418-21-1(Hazardous Substances Data)

Usage

General Description

2-(Bromomethyl)-2-phenyl-1,3-dioxolane is a chemical compound with the molecular formula C9H9BrO2. It is a colorless liquid with a molecular weight of 227.08 g/mol. 2-(BROMOMETHYL)-2-PHENYL-1,3-DIOXOLANE is commonly used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It is also used as a crosslinking agent in the production of polymers and as a solvent in various chemical processes. The presence of both a bromomethyl group and a phenyl group in the molecule gives it the potential for diverse chemical reactivity, making it useful in a variety of applications. However, it is important to handle this chemical with care due to its potential to cause skin and eye irritation, as well as respiratory issues if inhaled.

InChI:InChI=1/C10H11BrO2/c11-8-10(12-6-7-13-10)9-4-2-1-3-5-9/h1-5H,6-8H2

Upstream product

• 3674-77-9 2-methyl-2-phenyl-1,3-dioxolane 
• 39416-48-3 pyridinium hydrobromide perbromide 
• 98-85-1 1-Phenylethanol 
• 107-21-1 ethylene glycol 
• 98-86-2 acetophenone 
• 2425-28-7 2-Bromo-1-phenylethanol 
• 7381-30-8 2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane 
• 70-11-1 α-bromoacetophenone 
• 100-42-5 styrene 
• 936-51-6 2-phenyl-1,3-dioxolane 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 60207-37-6 1-((2-phenyl-1,3-dioxolane-2-yl)methyl)-1H-1,2,4-triazole 
• 1092851-56-3 1-[(2-phenyl-1,3-dioxolan-2-yl)methyl]-1H-imidazole hydrochloride 
• 1092851-57-4 1-[(2-phenyl-1,3-dioxolan-2-yl)methyl]-1H-1,2,4-triazole hydrochloride 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 33868-51-8 2-hydroxymethyl-2-phenyl-1,3-dioxolane 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 611-73-4 Benzoylformic acid 
• 1612188-31-4 C₁₁H₁₄O₂Se 
• 1612188-30-3 C₁₀H₁₂O₂Se 
• 1612188-29-0 C₁₃H₁₈O₃Se 
• 1612188-28-9 C₁₂H₁₆O₃Se 
• 1612188-27-8 C₁₆H₁₅NO₄Se 
• 1612188-26-7 C₁₃H₁₉NO₂Se 
• 1612188-25-6 C₁₂H₁₇NO₂Se 

Relevant articles and documents

Novel Dioxolane Ring Compounds for the Management of Phytopathogen Diseases as Ergosterol Biosynthesis Inhibitors: Synthesis, Biological Activities, and Molecular Docking

Thirty novel dioxolane ring compounds were designed and synthesized. Their chemical structures were confirmed by 1H NMR, HRMS, and single crystal X-ray diffraction analysis. Bioassays indicated that these dioxolane ring derivatives exhibited ex

Application of poly(vinylphenyltrimethylammonium tribromide) resin as an efficient polymeric brominating agent in the α-bromination and α-bromoacetalization of acetophenones

The applications of a new supported tribromide reagent based on poly(vinylbenzyltrimethylammonium hydroxide) resin (Amberlite 717) were reported. This supported tribromide resin was used directly in α-bromination and α-bromoacetalization of acetophenones without any other catalyst under mild conditions. The effects of solvents and the amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of α-bromo and α-bromoacetal of acetophenones were selectively obtained in excellent yields.

One-step for the preparation of α-haloacetal of ketones with N-bromosuccinimide/N-chlorosuccinimide (NBS/NCS) and ethylene glycol

A new process that could directly prepare α-haloacetal of ketones from various ketones with N-halosuccinimide (NBS/NCS) and ethylene glycol in one step without any other catalysts was reported. The effects of solvents, NBS/NCS and reaction temperature were investigated. Under the optimal condition, most of α-haloacetals of ketones were obtained in 90–100% yield.