345-66-4

Upstream product

• 95-52-3 2-Fluorotoluene 
• 98-88-4 benzoyl chloride 
• 455-84-5 4-fluoro-3-methylbonzoyl chloride 
• 71-43-2 benzene 
• 403-15-6 4-fluoro-3-methyl-benzoic acid 
• 452-75-5 4-chloro-2-fluorotoluene 
• 100-52-7 benzaldehyde 
• 345-65-3 C₁₄H₁₃FO 
• 51437-00-4 5-bromo-2-fluorotoluene 

Downstream Products

• 85588-38-1 3-bromomethyl-4-fluoro benzophenone 
• 834895-54-4 3-methyl-4-pyrrolidinobenzophenone 
• 834895-60-2 1-(3-methyl-4-pyrrolidinophenyl)-1-phenylprop-2-yn-1-ol 
• 834895-46-4 3-(3-methyl-4-pyrrolidinophenyl)-3-phenyl-3H-naphtho[2,1-b]pyran 
• 834895-47-5 3-(3-methoxy-4-pyrrolidinophenyl)-3-phenyl-3H-naphtho[2,1-b]pyran 
• 85588-41-6 6-fluoro-3-benzoylphenyl acetonitrile 

Relevant academic research and scientific papers

Intramolecular Charge Transfer Controls Switching Between Room Temperature Phosphorescence and Thermally Activated Delayed Fluorescence

Chemical modification of phenothiazine-benzophenone derivatives tunes the emission behavior from triplet states by selecting the geometry of the intramolecular charge transfer (ICT) state. A fundamental principle of planar ICT (PICT) and twisted ICT (TICT

Synthesis of fluorenone derivatives through Pd-catalyzed dehydrogenative cyclization

Palladium-catalyzed dual C-H functionalization of benzophenones to form fluorenones by oxidative dehydrogenative cyclization is reported. This method provides a concise and effective route toward the synthesis of fluorenone derivatives, which shows outstanding functional group compatibility.

Synthesis and photochromic properties of substituted 3H-naphtho[2,1-b] pyrans

The synthesis and spectroscopic properties of novel 3H-naphtho[2,1-b]pyrans are described. Subtle variation of the colour of the photo-generated merocyanine dyes derived from these naphthopyrans can be accomplished by controlling the steric interactions between a terminal pyrrolidine donor group and a proximal substituent.

Synthesis of substituted phenyl ketones via Pd-catalysed hydrodechlorination of their polychlorinated derivatives

The following compounds, 2- and 3-methylacetophenones, 2- and 3-methylbenzophenones, and 2,2'-, 2,3'- and 3,3'-dimethylbenzophenones have been synthesized through a Pd-catalysed hydrodechlorination of the corresponding dichlorinated derivatives. The reaction has been carried out under multiphase conditions at 30-50°C, by bubbling H2 at atmospheric pressure into a biphasic system constituted by an organic substrate solution (isooctane solvent) and an aqueous alkaline solution (50% aq KOH), in the presence of Pd/C (5% wt) and Aliquat 336 (tricaprylylmethylammonium chloride). Likewise, fluorinated aceto- and benzophenones (4-fluoro-3-methylacetophenone and 4-fluoro-3-methylbenzo-, 4-fluoro-2',3-dimethylbenzo-, 4-fluoro-3,3'-dimethylbenzophenones) have been prepared starting from the corresponding chlorinated methylfluoro and dimethyfluoro ketones. Under such conditions, the presence of the onium salt allows the reaction to proceed with a high chemoselectivity: chlorine is removed while both the reduction of the carbonyl group and/or fluorine removal are prevented.

6-Halogen derivatives of 2-(3-benzoylphenyl)propionic acid.

The synthesis of the 6-fluoro (I a), 6-chloro (I b) and 6-bromo (I c) derivatives of the known antiinflammatory agent 2-(3-benzoylphenyl)propionic acid (ketoprofen) is reported. The procedure employed involves the direct phase-transfer methylation of the