34523-87-0Relevant academic research and scientific papers
A simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl]fumarates: Potential intermediates in the synthesis of polysubstituted five- and six-membered heterocycles
?inkovec, Rok,Gro?elj, Uro?,Prek, Benjamin,Po?kaj, Marta,Ri?ko, Sebastijan,Svete, Jurij,Stanovnik, Branko
, p. 677 - 682 (2016/07/06)
In this communication, a simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl] fumarates is described. Methyl ketones were transformed by treatment with N,N-dimethylacetamide dimethyl acetal (DMADMA) into 3-dimethylamino-1-(subst
Reactions of methyl ketones and (hetero)arylcarboxamides with N,N-dimethylacetamide dimethyl acetal. A simple metal-free synthesis of 2,4,6-trisubstituted pyridines
Prek, Benjamin,Groelj, Uro,Kasuni, Marta,Zupani, Silvo,Svete, Jurij,Stanovnik, Branko
, p. 184 - 195 (2015/02/19)
Two metal-free syntheses of 2,4,6-trisubstituted pyridines 10a-m and 16a-j are described. N,N,6-Trimethyl-4-(substituted)pyridin-2-amines 10 were prepared from aryl or heteroaryl methyl ketones which were transformed with N,N-dimethylacetamide dimethyl ac
Clean and efficient synthesis of isoxazole derivatives in aqueous media
Dou, Guolan,Xu, Pan,Li, Qiang,Xi, Yukun,Huang, Zhibin,Shi, Daqing
, p. 13645 - 13653 (2014/01/06)
A series of 5-arylisoxazole derivatives were synthesized via the reaction of 3-(dimethyl-amino)-1-arylprop-2-en-1-ones with hydroxylamine hydrochloride in aqueous media without using any catalyst. This method has the advantages of easier work-up, mild rea
A SIMPLE PREPARATION OF SOME 4-METHYL-2H-PYRAN-2-ONES
Kepe, Vladimir,Polanc, Slovenko,Kocevar, Marijan
, p. 671 - 678 (2007/10/03)
A mehtod for the preparation of substituted 4-methyl-2H-pyran-2-ones (6-19) starting from methyl ketones (1), N,N-dimethylacetamide dimethyl acetal (2) and N-acylglycines (4) in acetic anhydride is described.
STUDY OF THE ESCHENMOSER SULFIDE CONTRACTION METHOD WITH AND WITHOUT A THIOPHILE
Corsaro, A.,Perrini, G.,Testa, M. G.,Chiacchio, U.
, p. 197 - 206 (2007/10/02)
Results obtained and observations made by applying the title method for the synthesis of enaminones 5a-o, using triphenylphosphine as a thiophile and triethylamine as a base, are reported.The product distributions of the deprotonations of α-phenacylthio iminium bromides with and without thiophile and those known from thiouronium and heterocyclic thionium analogs are compared.Key words: Enaminones; α-phenacylthio iminium bromides; disulfides; thiiranes.
A Simple Regioselective Synthesis of Pyrimidobenzimidazoles
Tseng, Shin-Shyong,Epstein, Joseph W.,Brabander, Herbert J.,Francisco, Gerardo
, p. 837 - 843 (2007/10/02)
2-Aminobenzimidazoles were reacted with enaminones in acetic acid to give pyrimidobenzimidazoles.With a substituted enaminone only one regioisomer was obtained.Structural assignments based on nmr and uv spectroscopy are presented.Possible pathways
Protonation and Acylation Reactions of Acyclic Enamino Ketones
Boehme, Horst,Traenka, Manfred
, p. 149 - 159 (2007/10/02)
α,β-Unsaturated β-dialkylamino ketones 4 are converted by means of tetrafluoroboric acid into thermodynamically stable Cα-protonated iminium salts 5. β-(Dialkylamino)vinyl ketones are shown to exist preferentially in the E-s-cis and E-s-trans c
New Synthesis of Isoxazoles and Isothiazoles. A Convenient Synthesis of Thioenaminones from Enaminones
Lin, Yang-i,Lang, Stanley, A.
, p. 4857 - 4860 (2007/10/02)
The reaction of 1-aryl-3-(dimethylamino)-2-propene-1-ones (enaminones) and 1-aryl-3-(dimethylamino)-2-propene-1-thiones (thioenaminones) with hydroxylamine-O-sulfonic acid gave, respectively, isoxazoles in 76-84 percent yields and isothiazoles in 60-65 pe
