34564-83-5Relevant academic research and scientific papers
Deaminative carbonylative coupling of alkylamines with styrenes under transition-metal-free conditions
Zhao, Fengqian,Li, Chong-Liang,Wu, Xiao-Feng
supporting information, p. 9182 - 9185 (2020/08/26)
A transition-metal-free deaminative carbonylation of alkylamines with styrenes has been developed. The reaction shows good functional group compatibility and various α,β-unsaturated ketones were obtained in moderate to good yields. The alkyl radical generated from Katritzky salts via base-promoted C-N bond cleavage is one of the key intermediates in this reaction. This journal is
Bisoxazoline-pincer ligated cobalt-catalyzed hydrogenation of alkenes
Ritz, Mikhaila D.,Parsons, Astrid M.,Palermo, Philip N.,Jones, William D.
supporting information, (2020/02/13)
The efficient and atom economical hydrogenation of alkenes using a novel bisoxazoline ligated cobalt complex has been developed. The hydrogenation of a variety of alkenes containing electron neutral and electron-donating groups proceeds in high yield, whi
Metal- and Oxidant-Free Alkenyl C?H/Aromatic C?H Cross-Coupling Using Electrochemically Generated Iodosulfonium Ions
Hayashi, Ryutaro,Shimizu, Akihiro,Davies, Jonathan A.,Ishizaki, Yu,Willis, Chris,Yoshida, Jun-ichi
, p. 12891 - 12895 (2018/09/14)
A three-step transformation consisting of 1) addition of electrochemically generated iodosulfonium ions to vinylarenes to give (1-aryl-2-iodoethoxy)sulfonium ions, 2) nucleophilic substitution by subsequently added aromatic compounds to give 1,1-diaryl-2-
Atom-efficient vinylic arylations with triarylbismuths as substoichiometric multicoupling reagents under palladium catalysis
Rao, Maddali L.N.,Jadhav, Deepak N.,Venkatesh, Varadhachari
experimental part, p. 4300 - 4306 (2011/02/24)
The first atom-efficient arylation of vinylic iodides was achieved by using triarylbismuths as substoichiometric multicoupling reagents under palladium catalysis. Vinylic iodides were efficiently coupled with electronically divergent triarylbismuths to furnish the corresponding arylated products in short reaction times.
Synthesis of 1,1-diaryl ethylenes by Cu-catalyzed arene C-H addition to aryl acetylenes
Bhilare, Sachin V.,Darvatkar, Nitin B.,Deorukhkar, Amol R.,Raut, Dilip G.,Trivedi, Girish K.,Salunkhe, Manikrao M.
scheme or table, p. 893 - 896 (2009/05/27)
An unprecedented copper-catalyzed C-H addition of arenes to aryl acetylenes provides a facile route to 1,1-diaryl ethylenes in moderate to excellent yields. Arylboronic acids were likewise used along with aryl acetylenes in generating 1,1-diaryl ethylene.
Preparation of prodrugs for selective drug delivery
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Page/Page column 102, (2010/02/11)
Synthesis of a chemical compound having the formula A-B-C that may serve for applications such as drug delivery where A is a chemiluminescent, moiety, B is a photochromic moiety, and C is a biologically active moiety where A-B-C may serve as a prodrug. No
Charge-transfer interactions in 4-donor 4′-acceptor substituted 1,1-diphenylethenes
Van Walree, Cornelis A.,Kaats-Richters, Veronica E. M.,Veen, Sandra J.,Wieczorek, Birgit,Van Der Wiel, Johanna H.,Van Der Wiel, Bas C.
, p. 3046 - 3056 (2007/10/03)
Two 1,1-diphenylethenes bearing either a 4-dimethylamino or 4-methoxy group as electron donor and a 4′-cyano group as electron acceptor, as well as compounds containing only a donor or acceptor functionality, were synthesized. The observation of strong fl
Substituent effects in solvolysis of 1,1-diphenylethyl p-nitrobenzoates. Symmetrically disubstituted and monosubstituted systems
Fujio, Mizue,Uddin, Md. Khabir,Kim, Hyun-Joong,Tsuno, Yuho
, p. 544 - 549 (2007/10/03)
The rates of solvolysis of 1,1-diarylethyl p-nitrobenzoates and chlorides were determined conductimetrically at 25 °C in 80% (v/v) aqueous acetone. Applying the Yukawa-Tsuno (Y-T) equation, the symmetrical (X = Y) subseries gave a precise additivity relationship for the whole substituent range with a rsym value of -3.78 and an rsym value of 0.77. While any Y subsets gave statistically less reliable Y-T correlations, the apparent ρ value changed significantly depending on the fixed Y substituents; the ρ value decreases with the more electron-donating fixed substituents Y, which is compatible with the Hammond shift of the transition state coordinate. Nevertheless, the concave correlations of the More O'Ferrall non-linearity relationship for any Y subsets are not in line with what is expected from the reactivity-selectivity relationship suggesting an anti-Hammond shift of transition state. However, we found a precise extended Bronsted relationship between the pKR+ values of 1,1-diarylethylenes and solvolysis rate process with a constant slope of α = 1.03 ± 0.03. This is direct evidence indicating that there is no significant shift of the transition-state coordinate over the whole range of substituent change. Copyright
