3488-57-1

Upstream product

• 62-53-3 aniline 
• 698-16-8 benzohydroximoyl chloride 
• 1527-91-9 N-phenylbenzamidine 
• 636-04-4 N-Phenylbenzothioamide 
• 60-29-7 diethyl ether 
• 64-17-5 ethanol 
• 7803-49-8 hydroxylamine 
• 4903-36-0 N-phenyl-benzimidoyl chloride 
• 100-52-7 benzaldehyde 
• 932-90-1 Benzaldoxime 
• 93-98-1 N-phenyl benzoyl amide 
• 98-88-4 benzoyl chloride 
• 873-67-6 benzonitrile oxide 

Downstream Products

• 3164-28-1 6-nitro-2-phenylbenzo[d]oxazole 
• 1527-91-9 N-phenylbenzamidine 
• 14562-01-7 3,4-diphenyl-1,2,4-oxadiazol-5(4H)-one 
• 65251-93-6 N-benzyloxy-N'-phenyl-benzamidine 
• 14562-00-6 (3,4-diphenyl-4H-[1,2,4]oxadiazol-5-ylidene)-phenyl-amine 
• 102-07-8 bis(diphenyl)urea 
• 22347-70-2 3,4-diphenyl-2-(toluene-4-sulfonylimino)-2,3-dihydro-2λ⁴-[1,2,3,5]oxathiadiazole 
• 35608-02-7 N-(3,4-diphenyl-4H-[1,2,4]oxadiazol-5-ylidene)-toluene-4-sulfonamide 
• 35608-01-6 N-(3,4-diphenyl-4H-[1,2,4]oxadiazol-5-ylidene)-benzenesulfonamide 
• 35608-04-9 4-chloro-N-(3,4-diphenyl-4H-[1,2,4]oxadiazol-5-ylidene)-benzenesulfonamide 
• 5319-63-1 2-phenyl-3-phenyl-4-phenyl-1,3,5,2-oxadiazoborole 
• 3815-50-7 3,4-diphenyl-3H-[1,2,3,5]oxathiadiazole 2-oxide 
• 65159-21-9 (3,4-diphenyl-4H-[1,2,4]oxadiazol-5-ylidene)-cyanamide 
• 64671-56-3 3,4-diphenyl-1,2,4-oxadiazole-5(4H)-thione 

Relevant academic research and scientific papers

Synthesis and substituent effect study on 13C NMR chemical shifts of 4-(substitue-phenyl)-6-methyl-3-phenyl-4H-1,2,4-oxadiazin-5(6H)-one

The twelve novel 4-(substituted-phenyl)-6-methyl-3-phenyl-4H-1,2,4-oxadiazin-5(6H)-one derivatives were synthesized by the reactions of N-Substituted-phenyl-benzamide oximes with 2-bromopropionyl chloride. The synthesized 1,2,4-oxadiazin-5-one derivatives

Iodine Promoted One-Pot Synthesis of 2-Aryl Benzoxazoles from Amidoximes via Oxidative Cyclization and Ring Contraction

A molecular I2-promoted one-pot synthesis of 2-aryl benzoxazoles has been developed by using amidoximes rather than the limited 2-aminophenols or 2-haloamides as substrates. The amidoxime substrates provided unique and efficient strategies for converting readily available aniline and benzaldehyde precursors into valuable chemicals. This transformation proceeded smoothly under transition-metal-free conditions through a sequential oxidative cyclization and ring contraction, and provided a potential route for introducing certain groups at any site of the scaffold.

A convenient one-pot synthesis of: N -substituted amidoximes and their application toward 1,2,4-oxadiazol-5-ones

The first direct one-pot approach for the synthesis of N-substituted amidoximes from secondary amides or the intermediate amides has been developed. Through the Ph3P-I2-mediated dehydrative condensation, a variety of N-aryl and N-alkyl amidoximes (R1(CNOH)NHR2, where R1 or R2 = aryl, alkyl, or benzyl) were readily afforded under mild conditions and short reaction times. The synthetic application of the obtained amidoximes has also been demonstrated through the formation of 1,2,4-oxadiazolones via base-mediated carbonylative cyclization with 1,1′-carbonyldiimidazole.

FeCl3·6H2O-mediated reaction of [60]fullerene with amidoximes

A FeCl3·6H2O-mediated reaction of [60]fullerene with amidoximes for the preparation of fulleroimidazolines has been presented. This reaction shows a wide substrate scope, and the products obtained from alkyl-substituted amidoximes ar

13C NMR substituent-induced chemical shifts in 4-(substituted phenyl)-3-phenyl-1,2,4-oxadiazol-5(4H)-ones (thiones)

In the present, study mostly novel ten 4-(substituted phenyl)-3-phenyl-1,2,4-oxadiazol-5(4H)-ones and ten 4-(substituted phenyl)-3-phenyl-1,2,4-oxadiazol-5(4H)-thiones were synthesized. These oxadiazole derivatives were characterized by IR, 1H

Practical synthesis of N -substituted cyanamides via tiemann rearrangement of amidoximes

A facile and general synthesis of various N-substituted cyanamides was accomplished by the Tiemann rearrangement of amidoximes with benzenesulfonyl chlorides (TsCl or o-NsCl) and DIPEA.