35000-22-7

Upstream product

• 75-31-0 isopropylamine 
• 107-05-1 3-chloroprop-1-ene 
• 106-95-6 allyl bromide 
• 67-64-1 acetone 
• 107-11-9 1-amino-2-propene 
• 75-26-3 isopropyl bromide 

Downstream Products

• 100614-70-8 N-allyl-N'-(3,4-dichloro-phenyl)-N-isopropyl-thiourea 
• 84053-74-7 N-Allyl-N-isopropyl-α-methyl-zimtsaeureamid 
• 64330-44-5 N-isopropyl-4-methyl-3-pyrrolin-2-one 

Relevant academic research and scientific papers

Stereodynamics of N-allyl-N-methyl-2-aminopropane. 1H and 13C{1H} DNMR studies. Molecular mechanics calculations

N-Allyl-N-methyl-2-aminopropane (AMAP) is a relatively simple tertiary amine that has a chiral center at the pyramidal nitrogen. The 1H and 13C{1H} dynamic nuclear magnetic resonance (NMR) spectra of AMAP show a higher temperature decoalescence due to slowing inversion-rotation at nitrogen and a more complex decoalescence at lower temperatures due to slowing isolated rotation about carbon-nitrogen bonds. A well-defined 1H NMR spectrum at 100 K is simulated accurately by invoking the presence of five equilibrium conformations including two conformers that interconvert rapidly at 100 K.

Palladium/Norbornene Catalyzed ortho Amination/Cyclization of Aryl Iodide: Process to 3-Methyl-indole Derivates and Controllable Reductive Elimination against the Second Amination

A palladium/norbornene cooperative catalyzed selective C-H bond amination of aryl iodides was explored, providing an efficient tool for constructing benzocyclic molecules. When ortho-substituted iodobenzene was involved, the C-H bond amination and following Heck cyclization efficiently delivered a 3-methyl-indole scaffold. On the other hand, we realized the controllable synthesis of monoaminated benzo-cyclobutanyl scaffold. The possible coordination of an installed terminal alkenyl group with palladium and steric hindrance were proposed to be responsible for the monoamination selectivity.

Phospha derivatives of Tris(2-aminoethyl)amine (tren) and tris(3-aminopropyl)amine (trpn): Synthesis and complexation studies with group 4 metals

The N,N′,N-triphenyl-substituted derivative of tris(2-aminoethyl)phosphine (Ph3-phospha-tren, P(CH2CH2NHR)3, R = Ph) and four derivatives of the related tris(3-aminopropyl)phosphine (phospha-trpn, P(CH2CH2CH2NHR)3, R = iPr, tBu, SitBuMe2, Ph) have been synthesized in addition to the parent phospha-trpn. Out of these ligand systems, only the N,N′,N-triphenyl-substituted phospha-trpn derivative P(CH2CH2CH2NHPh)3 was found to be suitable for coordination to group 4 metals. For titanium, zirconium, and hafnium, the C3-symmetric endo-P-configured dimethylamido complexes Ph[PN3]M(NMe2) of the former ligand have been prepared and converted into the corresponding triflates Ph[PN3]M(OTf). Starting from these triflates, the benzyl complexes Ph[PN3]M(Bn) (M = Ti, Zr, Hf) have been obtained via reaction with Bn2Mg(THF)2. In case of titanium, the benzyl species Ph[PN3]Ti(Bn) is prone to thermal elimination of toluene, which results in the formation of a cyclometalated species. These findings are discussed in context with the very few group 4 trisamidophosphine complexes that have been reported earlier.

Pseudopeptide, synthesis method, reagent and applications

The invention concerns a pseudopeptide of at least 6 amino acids comprising at least a unit selected among the general formulae (I) and/or (II) wherein: R1, R2 and R3 each independently of one another represent a side-chain of amino acids and can be identical or different; X represents an oxygen or sulphur atom. The invention also concerns its synthesis process, a reagent containing it, a detection kit comprising such a reagent, a method for detecting an antigen or an antibody using said pseudopeptide, and antibody or and anti-idiotype and finally a therapeutic composition.

Oxidative addition of N-aminophthalimide to conjugated and nonconjugated alkylazoalkanes

A series of γ,δ-unsaturated azo compounds was prepared by thermal isomerization of allylalkylhydrazones obtained from the simplest carbonyl compounds. The oxidation of N-aminophthalimide with lead tetraacetate in the presence of these unsaturated compound

Carbamoylphenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators

Compounds of the formula (I) or salts thereof in which R1, R3=H, (subst.) hydrocarbon radical (HC) or (subst.) heterocyclyl which, including substituents, have 1-30 carbon atoms, R2=R0—Q0—, in which R

PHOSPHONIUM DIAZA-DIYLIDS AND AZA-YLDIID AS NEW AND EFFICIENT REAGENTS FOR PRIMARY AND SECONDARY AMINES SYNTHESIS

Metallated aminophosphonium ylids, diaza-diylids and aza-yldiid, are investigated as reagents for primary and secondary amines synthesis.

DIRECT REGIO- AND STEREO-SELECTIVE LITHIATION OF SECONDARY ALLYL AND METHYLALLYL AMINES: A NEW TYPE OF γ-AMINATED ORGANOLITHIUM REAGENTS IN ORGANIC SYNTHESIS

Several secondary allyl and methylallylamines (6) have been regio- and stereo-selectively lithiated with t-butyl-lithium, giving the corresponding sp2 γ-aminated organolithium intermediates (7), which by reaction with electrophiles D2O, Me2S2,