351377-62-3

Upstream product

• 351378-62-6 5-iodo-2-methoxy-3-methyl-phenol 
• 244126-22-5 toluene-4-sulfonic acid 2-hydroxy-3-methyl-phenyl ester 
• 351379-12-9 3-Benzyloxy-1-iodo-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-benzene 
• 351378-60-4 2-hydroxy-5-iodo-3-methylphenyl 4-methylbenzenesulfonate 
• 351380-16-0 toluene-4-sulfonic acid 5-iodo-2-methoxy-3-methyl-phenyl ester 
• 351379-10-7 2-hydroxymethyl-3-iodo-6-methoxy-5-methyl-phenol 
• 488-17-5 3-methylbenzene-1,2-diol 
• 351380-02-4 [2-[3-benzyloxy-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-phenyl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-methyl-carbamic acid tert-butyl ester 
• 886450-24-4 [2-(2,2-di-tert-butyl-8-methoxy-7-methyl-4H-benzo[1,3,2]dioxasilin-5-yl)-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid tert-butyl ester 
• 886450-26-6 [2-(3-benzyloxy-2-hydroxymethyl-4-methoxy-5-methyl-phenyl)-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid tert-butyl ester 
• 351377-69-0 5-[2-azido-2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-2,2-di-tert-butyl-8-methoxy-7-methyl-4H-benzo[1,3,2]dioxasiline 
• 886450-07-3 3-azido-4-(2,2-di-tert-butyl-8-methoxy-7-methyl-4H-benzo[1,3,2]dioxasilin-5-yl)-butane-1,2-diol 
• 886450-25-5 [1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-(3-hydroxy-2-hydroxymethyl-4-methoxy-5-methyl-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 351377-68-9 4-(2,2-di-tert-butyl-8-methoxy-7-methyl-4H-benzo[1,3,2]dioxasilin-5-yl)-but-2-en-1-ol 

Downstream Products

• 886450-29-9 [1-[3-benzyloxy-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-benzyl]-2-(9-benzyloxymethyl-6-hydroxy-5-methoxy-4-methyl-6,9-dihydro-7H-[1,3]dioxolo[4,5-h]isoquinolin-8-yl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 851122-04-8 [2-(5-allyloxy-1-benzyloxymethyl-4-hydroxy-7,8-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-(3-benzyloxy-2-hydroxymethyl-4-methoxy-5-methyl-benzyl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 851121-89-6 [2-(5-allyloxy-1-benzyloxymethyl-7,8-dimethoxy-6-methyl-4-oxo-3,4-dihydro-1H-isoquinolin-2-yl)-1-(3-benzyloxy-2-formyl-4-methoxy-5-methyl-benzyl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 851122-06-0 C₄₆H₅₆N₂O₇Si 
• 851121-90-9 C₄₃H₄₆N₂O₈ 
• 851121-96-5 C₃₉H₄₈N₂O₉Si 
• 851122-08-2 C₃₉H₄₆N₂O₉Si 
• 851122-07-1 C₃₉H₄₈N₂O₈Si 
• 851121-95-4 C₃₉H₅₀N₂O₇Si 
• 851121-93-2 C₃₂H₃₀N₂O₉ 
• 851121-92-1 C₃₂H₃₀N₂O₈ 
• 886450-28-8 [1-[3-benzyloxy-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-benzyl]-2-(1-benzyloxymethyl-4-hydroxy-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 351378-20-6 [1-[3-benzyloxy-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-benzyl]-2-(1-benzyloxymethyl-5,7,8-trimethoxy-6-methyl-4-oxo-3,4-dihydro-1H-isoquinolin-2-yl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 351378-05-7 [1-[3-benzyloxy-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-benzyl]-2-(9-benzyloxymethyl-5-methoxy-4-methyl-6-oxo-6,9-dihydro-7H-[1,3]dioxolo[4,5-h]isoquinolin-8-yl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

The solution to a deep stereochemical conundrum: Studies toward the tetrahydroisoquinoline alkaloids

(Chemical Equation Presented) Facile construction of subunits 1 and 2 allowed the rapid assembly of the pentacyclic ring system 3 of the cytotoxic tetrahydroisoquinoline alkaloids. A surprising participation reaction was discovered, which necessitated rev

Total synthesis of cribrostatin IV: Fine-tuning the character of an amide bond by remote control

We report the enantioselective total synthesis of cribrostatin IV (1). Key features of this synthesis involve the convergent coupling of two highly functionalized homochiral components followed by a "lynchpin" Mannich cyclization to establish the pentacyc