35534-19-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(Methylamino)-1-phenylethanone is utilized as a therapeutic agent for the treatment of specific medical conditions such as attention deficit hyperactivity disorder (ADHD) and obesity. Its stimulant properties aid in enhancing focus and reducing weight, although its use is strictly regulated due to its high potential for abuse.
Used in Recreational Context:
Despite its severe legal and health ramifications, methamphetamine is illicitly employed as a recreational drug. Its ability to induce a sense of euphoria, increased energy, and alertness makes it a sought-after substance in the context of parties and other social settings, although this use is strongly discouraged due to the associated risks of addiction and severe health consequences.

InChI:InChI=1/C9H11NO/c1-10-7-9(11)8-5-3-2-4-6-8/h2-6,10H,7H2,1H3

Upstream product

• 5840-76-6 sarcosine-N-carboxyanhydride 
• 71-43-2 benzene 
• 124-40-3 dimethyl amine 
• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 
• 74-89-5 methylamine 
• 6476-40-0 cis-1-methyl-2-benzoyl-3-phenylaziridine 
• 74300-28-0 ((2R,3R)-1-Methyl-3-p-tolyl-aziridin-2-yl)-phenyl-methanone 
• 100-42-5 styrene 
• 123-39-7 N-Methylformamide 
• 25808-30-4 2-(methylamino)acetonitrile hydrochloride 
• 593-51-1 methylamine hydrochloride 
• 74879-77-9 [(2S,3S)-1-Methyl-3-(3-nitro-phenyl)-aziridin-2-yl]-phenyl-methanone 
• 74300-26-8 [(2R,3R)-3-(4-Bromo-phenyl)-1-methyl-aziridin-2-yl]-phenyl-methanone 

Downstream Products

• 65-85-0 benzoic acid 
• 35746-37-3 N-methyl-N-(2-oxo-2-phenylethyl)acetamide 
• 114376-13-5 (3S,4R,5R)-clausenamidone 
• 65058-52-8 N-methyl (S)-2-hydroxy-2-phenylethylamine 
• 495-42-1 (-)-Halostachine 
• 68579-60-2 2-(methylamino)-1-phenylethanol 
• 112698-39-2 2-amino-6--5-nitro-4(3H)-pyrimidinone 
• 56157-01-8 N,4-dimethyl-N-(2-oxo-2-phenylethyl)benzenesulfonamide 

Relevant academic research and scientific papers

A METAL FREE PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED CARBONYL COMPOUNDS FROM ALKENES

The present invention discloses a novel metal free process for the regioselective synthesis of α-substituted carbonyl compounds of formula I from alkene, X is selected from the following compounds (A, B).

Regioselective oxo-amination of alkenes and enol ethers with N-bromosuccinimide-dimethyl sulfoxide combination: A facile synthesis of α-amino-ketones and esters

An unprecedented conversion of alkenes and enol ethers to the corresponding α-imido carbonyl compounds with excellent regioselectivity and yields has been developed. This oxo-amination process employs readily available N-bromosuccinimide (NBS) and secondary amines as N-sources and dimethyl sulfoxide (DMSO) as the oxidant and also leads to the production of amino alcohols in a single step on reduction, thus broadening the scope of this operationally simple reaction. For the first time, the formation of reactive Me2S+-O-Br species generated by the interaction of NBS with DMSO has been proven.

Superelectrophilic chemistry of amino-nitriles and related substrates

The superacid-promoted Houben/Hoesch reactions of amino-nitriles and related compounds have been studied. The nitriles form dicationic electrophiles and react with benzene in fair to good yields (12-95%). The intermediate iminium ions may also be reduced to the benzylic amines by NaBH4 or H 2.

SYNTHESIS AND STEREOCHEMISTRY OF 2,2,3-TRIMETHYL-5-ARYL-4-AROYLOXYZOLIDINES

cis-2,2,3-Trimethyl-5-aryl-4-aroyloxazolidines were obtained by heating complex boron trifluoride salts of trans-1-methyl-2-aryl-3-aroylaziridines with acetone.The reaction of complex boron trifluoride salts of cis-1-methyl-2-aryl-3-aroylaziridines leads to substituted benzaldehydes and ω-N-methylaminoacetophenones.