35836-41-0

Basic information

• Product Name: (2,3-dihydroxy-4-methoxyphenyl)(phenyl)methanone
• CAS NO: 35836-41-0
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.2427
• Mol File: 35836-41-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 417.4°C at 760 mmHg
• Flash Point: 160.1°C
• Density: 1.296g/cm³
• Vapor Pressure: 1.46E-07mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: (2,3-dihydroxy-4-methoxyphenyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3-dihydroxy-4-methoxyphenyl)(phenyl)methanone(35836-41-0)
• EPA Substance Registry System: (2,3-dihydroxy-4-methoxyphenyl)(phenyl)methanone(35836-41-0)

Safety Data

• Hazardous Substances Data: 35836-41-0(Hazardous Substances Data)

Usage

General Description

(2,3-dihydroxy-4-methoxyphenyl)(phenyl)methanone, also known as dihydroxyacetophenone, is a chemical compound with the molecular formula C14H12O4. It is a ketone derivative with two hydroxyl groups and a methoxy group attached to a benzene ring. (2,3-dihydroxy-4-methoxyphenyl)(phenyl)methanone has been found in various plant species and is known to exhibit antioxidant and anti-inflammatory properties. It has also been studied for its potential use in pharmaceuticals and cosmetic products due to its beneficial effects on skin health and aging. Additionally, it has been implicated in the biosynthesis of secondary metabolites in certain plant species.

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Relevant articles and documents

Determination of the sequential order of acidity in a polyhydroxylated benzophenone series. Consequence on the oxidation reaction in relation to hepatotoxicity

The pKa values of successive acid-base equilibria involved in the pyrogallol ring ionisation of exifone, 2,3,4-trihydroxybenzophenone 1, and related methoxy derivatives were determined by UV-VIS absorption spectrometry and potentiometric titration.Due to strong intramolecular hydrogen bonding, the sequential order of acidity of the three hydroxy groups of 1 was found to be 4-OH > 3-OH > 2-OH.The polyhydroxylated benzophenones were oxidized to 3,4-quinone only in a narrow range of acidity in which the monoanionic 4-olate species predominated in solution.The attachment of an amino-alcohol residue resulted in the trapping of the transient 3,4-quinone and provided a convenient route to novel 1,4-benzoxazine derivatives.Cytotoxicity experiments in rat hepatocytes indicated that some of these compounds were significantly less toxic than the parent exifone.