3615-44-9 Usage
Description
D-Glucose is phosphorylated by glucokinase and three tissue-specific hexokinases to produce glucose-6-phosphate in humans. D-Mannoheptulose is a heptose that inhibits glucokinases and hexokinases from diverse organisms through competition with D-glucose (Ki = 0.25 mM). It blocks glucose oxidation and glucose-mediated insulin release from pancreatic islet cells. D-Mannoheptulose prevents the conversion of glucose to glucose-6-phosphate that can mediate the activation of the carbohydrate response element binding protein. By blocking glucose phosphorylation, D-mannoheptulose causes transient hyperglycemia in dogs when given at 1 g/kg but not at 8 mg/kg, although postprandial energy expenditure is increased at the lower dose.
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 3615-44-9 differently. You can refer to the following data:
1. Mannoheptulose occurs naturally in avocado fruit. It is used for normalizing insulin levels and reducing weight.
2. Mannoheptulose occurs naturally in avocado fruit.
Check Digit Verification of cas no
The CAS Registry Mumber 3615-44-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,1 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3615-44:
(6*3)+(5*6)+(4*1)+(3*5)+(2*4)+(1*4)=79
79 % 10 = 9
So 3615-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H14O7/c8-1-3-4(10)5(11)6(12)7(13,2-9)14-3/h3-6,8-13H,1-2H2/t3?,4-,5-,6?,7?/m1/s1
