366-68-7

Basic information

• Product Name: 1,2-BIS-(4-FLUOROPHENYL)ETHANONE
• Synonyms: 1,2-BIS-(4-FLUOROPHENYL)ETHANONE;4'-Fluoro-2-(4-fluorophenyl)acetophenone
• CAS NO: 366-68-7
• Molecular Formula: C₁₄H₁₀F₂O
• Molecular Weight: 232.23
• Mol File: 366-68-7.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-BIS-(4-FLUOROPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-BIS-(4-FLUOROPHENYL)ETHANONE(366-68-7)
• EPA Substance Registry System: 1,2-BIS-(4-FLUOROPHENYL)ETHANONE(366-68-7)

Safety Data

• Hazardous Substances Data: 366-68-7(Hazardous Substances Data)

Usage

Uses

1,2-Bis(4-fluorophenyl)ethanone is a useful synthetic compound.

Upstream product

• 403-43-0 4-fluorobenzoyl chloride 
• 1196070-08-2 1,2-bis(4-fliorophenyl)-2-oxoethyl pivalate 
• 1196070-06-0 1,2-bis(4-fluorophenyl)-2-oxoethyl methanesulfonate 
• 1196070-07-1 1,2-bis(4-fluorophenyl)-2-oxoethyl acetate 
• 5216-31-9 1,2-bis(4-fluorophenyl)acetylene 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 459-56-3 4-fluorobenzylic alcohol 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 462-06-6 fluorobenzene 
• 456-04-2 2-Chloro-4'-fluoroacetophenone 
• 579-39-5 1,2-bis(4-fluorophenyl)ethane-1,2-dione 
• 405-50-5 p-Fluorophenylacetic acid 

Downstream Products

• 798-59-4 tris-(4-fluoro-phenyl)-ethene 
• 582-71-8 α-chloro-4,4'-difluoro-stilbene 
• 1373156-20-7 3-[4-[2,3-bis(4-fluorophenyl)-3-oxo-propyl]phenyl]isoxazole-5-carboxylic acid 
• 1373156-52-5 C₂₇H₂₁F₂NO₄ 
• 565-14-0 α,α'-dibromo-α-chloro-4,4'-difluoro-bibenzyl 
• 2729-18-2 1-(4-fluorophenyl)-2-(4-methoxyphenyl)ethan-1-one 
• 83882-76-2 2-(4-Fluorophenyl)-1-(4-hydroxyphenyl)ethanone 
• 456-22-4 4-Fluorobenzoic acid 
• 366-63-2 4-fluoro-N-phenylbenzamide 
• 459-57-4 4-fluorobenzaldehyde 
• 1609025-09-3 2,3-bis(4-fluorophenyl)-7-hydroxyquinoxaline-6-carboxylic acid 
• 133235-77-5 (+/-)-1,2-Bis(4-fluorophenyl)ethylamine hydrochloride 

Relevant articles and documents

Diazaphosphinyl radical-catalyzed deoxygenation of α-carboxy ketones: A new protocol for chemo-selective C-O bond scission: Via mechanism regulation

C-O bond cleavage is often a key process in defunctionalization of organic compounds as well as in degradation of natural polymers. However, it seldom occurs regioselectively for different types of C-O bonds under metal-free mild conditions. Here we report a facile chemo-selective cleavage of the α-C-O bonds in α-carboxy ketones by commercially available pinacolborane under the catalysis of diazaphosphinane based on a mechanism switch strategy. This new reaction features high efficiency, low cost and good group-tolerance, and is also amenable to catalytic deprotection of desyl-protected carboxylic acids and amino acids. Mechanistic studies indicated an electron-transfer-initiated radical process, underlining two crucial steps: (1) the initiator azodiisobutyronitrile switches originally hydridic reduction to kinetically more accessible electron reduction; and (2) the catalytic phosphorus species upconverts weakly reducing pinacolborane into strongly reducing diazaphosphinane. This journal is

Method for preparing diphenylethanone from benzyl alcohol through photocatalytic one-step method

The present invention relates to a method for preparing diphenylethanone from benzyl alcohol through a photocatalytic one-step method. According to the method, diphenylethanone is directly prepared byusing inexpensive benzyl alcohol as a raw material under the action of a solid photocatalyst; and the reaction process comprises: mixing benzyl alcohol, a catalyst and an acetonitrile solvent are mixed, placing in a pressure container, replacing with an inert gas, and carrying out illumination stirring at a room temperature, wherein the reaction time is more than 1 h, the catalyst is easily separated from the reaction system after the reaction and can be recycled multiple times, and the separation yield of diphenylethanone is up to 81%.

Selective reduction of carbonyl groups in the presence of low-valent titanium reagents

The chemoselective reduction of several structurally diverse compounds containing carbonyl groups was achieved in the presence of low-valent titanium reagents. This novel synthetic method provides easy access to highly selective reduction of carbonyl groups, and possesses several advantages including one-step procedure, convenient manipulation, good to excellent yields, and short reaction times.