367520-82-9

Upstream product

• 155612-31-0 (2R)-2-methyl-2-p-tolyl-3-butenal 
• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 87959-45-3 1-(2,2-dibromo-1-methylcyclopropyl)-4-methylbenzene 
• 124-38-9 carbon dioxide 
• 63099-51-4 1-(buta-2,3-dien-2-yl)-4-methylbenzene 
• 74-85-1 ethene 
• 1258011-46-9 trimethyl(2-p-tolylallyloxy)silane 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 156817-47-9 (Z)-2-(p-methylphenyl)-2-buten-1-ol 
• 877077-49-1 (R)-(+)-2-(methoxycarbonyl)-2-(4-methylphenyl)propionic acid 
• 127047-07-8 (R)-(+)-methyl 3-hydroxy-2-methyl-2-(4-methylphenyl)propionate 

Downstream Products

• 155612-31-0 (2R)-2-methyl-2-p-tolyl-3-butenal 
• 105556-82-9 (R)-3-methyl-3-(p-tolyl)pent-4-enal 
• 105556-81-8 (3R)-(E)-1-methoxy-3-methyl-3-p-tolylpenta-1,4-diene 
• 147129-23-5 (S)-4-methyl-4-(p-tolyl)hex-5-enal 
• 105556-94-3 (3S)-3-methyl-3-p-tolyl-4-pentenal 
• 105556-96-5 (2R)-2-methyl-2-p-tolyl-3-butenyl(R)-α-methoxyphenylacetate 

Relevant academic research and scientific papers

Construction of All-Carbon Chiral Quaternary Centers through CuI-Catalyzed Enantioselective Reductive Hydroxymethylation of 1,1-Disubstituted Allenes with CO2

A catalytic enantioselective construction of all-carbon chiral quaternary centers through reductive hydroxymethylation of 1,1-disubstituted allenes with CO2 has been developed. In the presence of a copper/Mandyphos catalyst, CO2 is t

Asymmetric total synthesis of (R)-α-cuparenone, (S)-cuparene and formal synthesis of (R)-β-cuparenone through Meinwald rearrangement and ring closing metathesis (RCM) reaction

Asymmetric synthesis of enantiopure cuparenoid sesquiterpenes (R)-α-cuparenone, (S)-cuparene and a formal synthesis of (R)-β-cuparenone was presented in this article. Meinwald rearrangement of an enantiopure trisubstituted 2,3-epoxy alcohol derivative was

Nickel-catalyzed enantioselective hydrovinylation of silyl-protected allylic alcohols: An efficient access to homoallylic alcohols with a chiral quaternary center

Asymmetric hydrovinylation of silyl-protected allylic alcohols catalyzed by nickel complexes of chiral spiro phosphoramidite ligands was developed. A series of homoallylic alcohols with a chiral quaternary center were produced in high yields (up to 97%) and high enantioselectivities (up to 95% ee). The reaction provides an efficient method for preparing bifunctional compounds with a chiral quaternary carbon center.

Asymmetric Construction of Quaternary Carbons from Chiral Malonates : Total Syntheses of (+)-Epilaurene and (-)-Isolaurene

Enantiomerically pure (+)-epilaurene and (-)-isolaurene were obtained from the chiral malonic acid ester (R)-(+)-4, via the 4-methyl-4-p-tolylhex-5-en-1-al (S)-9 prepared by double Wittig reaction under sonication, which underwent subsequent radical induc