3743-28-0

Basic information

• Product Name: M-HYDROXYBENZANILIDE
• Synonyms: M-HYDROXYBENZANILIDE;3-HYDROXYBENZANILIDE;N-(3-hydroxyphenyl)benzamide
• CAS NO: 3743-28-0
• Molecular Formula: C₁₃H₁₁NO₂
• Molecular Weight: 213.23
• Mol File: 3743-28-0.mol
• Article Data: 19

Chemical Properties

• Melting Point: 153 °C
• Boiling Point: 300.1°Cat760mmHg
• Flash Point: 135.3°C
• Appearance: /
• Density: 1.278g/cm³
• Vapor Pressure: 0.000229mmHg at 25°C
• Refractive Index: 1.675
• PKA: 9.57±0.10(Predicted)
• CAS DataBase Reference: M-HYDROXYBENZANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: M-HYDROXYBENZANILIDE(3743-28-0)
• EPA Substance Registry System: M-HYDROXYBENZANILIDE(3743-28-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 3743-28-0(Hazardous Substances Data)

Usage

General Description

M-Hydroxybenzanilide is a chemical compound commonly used in the production of pharmaceuticals and dyes. Also known as 2'-Hydroxyacetanilide, it is a white solid with a molecular formula of C13H11NO2 and a molecular weight of 213.23 g/mol. M-Hydroxybenzanilide has antimicrobial properties and is often utilized as a preservative in various products, including cosmetics and personal care items. It is also used as an intermediate in the synthesis of other organic compounds and dyes. Additionally, this compound has shown potential as an anti-inflammatory and analgesic agent in pharmaceutical research. However, it should be handled and stored with caution due to its potential irritant and harmful effects on human health and the environment.

InChI:InChI=1/C13H11NO2/c15-12-8-4-5-10(9-12)13(16)14-11-6-2-1-3-7-11/h1-9,15H,(H,14,16)

Upstream product

• 93-97-0 benzoic acid anhydride 
• 108-88-3 toluene 
• 591-27-5 m-Hydroxyaniline 
• 93-99-2 benzoic acid phenyl ester 
• 85915-70-4 acide hydroxy-4 N-benzoyl anthranilique 
• 10364-94-0 1-benzoylimidazole 
• 65-85-0 benzoic acid 
• 626-02-8 3-Iodophenol 
• 100-47-0 benzonitrile 
• 52252-80-9 N-(3-oxocyclohex-1-en-1-yl)benzamide 
• 121-47-1 3-aminobenzenesulfonic acid 
• 108-46-3 recorcinol 
• 98-88-4 benzoyl chloride 
• 583-04-0 vinyl benzoate 

Downstream Products

• 46457-64-1 N-benzyl-3-hydroxybenzenamine 
• 1152493-38-3 3-benzamidophenyl dimethylcarbamate 
• 110193-99-2 benzoic acid-[3-(4-nitro-phenacyloxy)-anilide] 
• 1184787-01-6 C₁₇H₁₉NO₄ 

Relevant articles and documents

Practical Chemoselective Acylation: Organocatalytic Chemodivergent Esterification and Amidation of Amino Alcohols with N-Carbonylimidazoles

Chemoselective transformations are a cornerstone of efficient organic synthesis; however, achieving this goal for even simple transformations, such as acylation reactions, is often a challenge. We report that N-carbonylimidazoles enable catalytic chemodivergent aniline or alcohol acylation in the presence of pyridinium ions or 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), respectively. Both acylation reactions display high and broad chemoselectivity for the target group. Unprecedented levels of chemoselectivity were observed in the DBU-catalyzed esterification: A single esterification product was obtained from a molecule containing primary aniline, alcohol, phenol, secondary amide, and N?H indole groups. These acylation reactions are highly practical as they involve only readily available, inexpensive, and relatively safe reagents; can be performed on a multigram scale; and can be used on carboxylic acids directly by in situ formation of the acylimidazole electrophile.

Novel 3/4-((Substitutedbenzamidophenoxy)methyl)-N-hydroxybenzamides/propenamides and its use

The present invention relates to novel 3/4-((substituted benzamidophenoxy) methyl) -N-hydroxy benzamide/propenamide, as a histone deacetylase (HDAC) inhibitor, and to an anticancer composition comprising the same as an active ingredient. More specifically

Structure–activity relationship investigation of benzamide and picolinamide derivatives containing dimethylamine side chain as acetylcholinesterase inhibitors

A series of benzamide and picolinamide derivatives containing dimethylamine side chain (4a–4c and 7a–7i) were synthesised and evaluated for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity in vitro. Structure–activity relat