37513-99-8

Upstream product

• 18369-65-8 3-acetyloxy-5,5-dimethyl-2-cyclohexenone 
• 57918-73-7 3-acetoxy-cyclohex-2-enone 
• 126-81-8 dimedone 
• 3471-13-4 dimedone 
• 108-24-7 acetic anhydride 
• 1445-45-0 Trimethyl orthoacetate 
• 631-57-2 Acetyl cyanide 

Downstream Products

• 55634-19-0 2-[1-(allyloxyamino)ethylidene]-5,5-dimethylcyclo-hexane-1,3-dione 
• 55634-21-4 5,5-Dimethyl-2-(1-propoxyamino-ethylidene)-cyclohexane-1,3-dione 
• 55634-11-2 2-[1-(ethoxyamino)ethylidene]-5,5-dimethylcyclohexane-1,3-dione 
• 51300-52-8 1-(4-methoxyphenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one 
• 79699-83-5 2-ethyl-2,4,4,6,6-pentachloro-5,5-dimethyl-1,3-cyclohexanedione 
• 79699-89-1 2-ethyl-4,4,6,6-tetrachloro-5,5-dimethyl-1,3-cyclohexanedione 
• 343854-87-5 2-ethyl-2-chlorodimedone 
• 79700-00-8 5-ethyl-3,3-dimethyl-1,2,4-cyclopentanetrione 
• 23014-42-8 2-acetyl-3-amino-5,5-dimethyl-2-cyclohexen-one 
• 16315-16-5 3,6,6-trimethyl-1⁽²⁾,5,6,7-tetrahydro-4H-indazole-4-one 
• 53173-69-6 3,6,6-trimethyl-6,7-dihydro-1,2-benzisoxazol-4(5H)-one 
• 101386-03-2 2-acetyl-2-chloro-5,5-dimethyl-1,3-cyclohexanedione 

Relevant academic research and scientific papers

Activator-free reactions of carboxylic ortho esters with cyclic β-diketones

The reaction mechanisms of cyclic 1,3-diketones with trialkyl orthoformates and trimethyl orthoacetate in the absence of activators were theoretically and experimentally studied. The reactions proceed via C-C-coupling of the ionized forms of the reactants giving dialkyl acetals, which further transform into vinyl ethers. The reactions of the latter with ortho esters afford aldehydes (ketones). Related 2-acetylcyclopentanone reacts with trimethyl orthoacetate under argon to form a mixture of methyl enol ethers, whereas in the presence of air oxygen dimethyl glutarate is formed.

Synthesis of novel triketone-based acidichromic colorants

This letter presents the synthesis and evaluation of two novel triketone-containing acidichromic colorants. Analysis results indicate that both prepared triketone-containing compounds undergo two distinct and reversible color changes under both strongly acidic and basic conditions. Thus, a pH sensitive triketone functional group is introduced for the first time to design and synthesize acidichromic colorants.

Method for acylating cyclic compounds

The method of this invention prepares acylated cyclic compounds by contacting phenyl esters as acylating agents with cyclic compounds in the presence of a cyanide or fluoride catalyst.

Molybdenum hexacarbonyl promoted ring-opening of hydroxyimino isoxazoles: Unexpected pyrazole formation

Fused isoxazoles underwent reductive ring-opening in the presence of molybdenum hexacarbonyl to give the corresponding β-disubstituted compounds. 3,6,6-Trimethyl-6,7-dihydro-1,2-benzisoxazol-4(5H)-one oxime underwent reductive ring-opening in the presence of molybdenum hexacarbonyl to give 3,6,6-trimethyl-6,7-dihydro-1H-indazol-4(5H)-one. A mechanism is proposed.

The cyanide catalyzed isomerization of enol esters derived from cyclic 1,3-diketones

Cross-over experiments unveil that the mechanism of the title reaction consists in cleavage of enol esters by cyanide with transient formation of acyl cyanides. These react as 'soft' C-acylating agents with the enolates freed in the initial step. Use is made of the acyl cyanide derived from pyrrole-2-carboxylic acid to set up the triketide type skeleton 12 of the antibiotic pyoluteorin 16. The aromatization of 12 with mercuric acetate gave the pyrrolo[a]indolone 18.

Synthesis of Conjugated Enamino Compounds Inhibiting Photosynthetic Electron Transport

2--1,3-dicarbonyl compounds were synthesized as photosynthetic electron transport (PET) inhibitors because of their structural resemblance to the potent new PET inhibitors "cyanoacrylates".Their functionalities were different f