37964-77-5Relevant articles and documents
The Concise Synthesis of Unsymmetric Triarylacetonitriles via Pd-Catalyzed Sequential Arylation: A New Synthetic Approach to Tri- and Tetraarylmethanes
Nambo, Masakazu,Yar, Muhammad,Smith, Joel D.,Crudden, Cathleen M.
, p. 50 - 53 (2015/07/28)
The selective synthesis of multiarylated acetonitriles via sequential palladium-catalyzed arylations of chloroacetonitrile is reported. The three aryl groups are installed via a Pd-catalyzed Suzuki-Miyaura cross coupling reaction followed by back-to-back C-H arylations to afford triarylacetonitriles in three steps with no over-arylation at any step. The triarylacetonitrile products can be converted into highly functionalized species including tetraarylmethanes. This new strategy provides rapid access to a variety of unsymmetrical tri- and tetraarylmethane derivatives from simple, readily available starting materials. (Chemical Presented)
Photolysis of Triarylacetonitriles. A Novel Photochemical Generation of Phenyl(cyano)carbene
Shi, Min,Okamoto, Yoshiki,Takamuku, Setsuo
, p. 1044 - 1054 (2007/10/02)
Upon UV irradiation in methanol, triarylacetonitrile underwent a novel α,α-elimination of two aryl groups to give biaryl and α-methoxyarylacetonitrile.However, when a methoxy group was introduced into the phenyl group, another photochemical process which gave the corresponding triarylmethane and methoxytriarylmethane as major products took place simultaneously.
