38158-65-5

Basic information

• Product Name: N,4-dimethyl-N-phenylaniline
• Synonyms: N,4-dimethyl-N-phenylaniline
• CAS NO: 38158-65-5
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.2756
• Mol File: 38158-65-5.mol
• Article Data: 91

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,4-dimethyl-N-phenylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N,4-dimethyl-N-phenylaniline(38158-65-5)
• EPA Substance Registry System: N,4-dimethyl-N-phenylaniline(38158-65-5)

Safety Data

• Hazardous Substances Data: 38158-65-5(Hazardous Substances Data)

Upstream product

• 624-31-7 4-tolyl iodide 
• 100-61-8 N-methylaniline 
• 106-38-7 para-bromotoluene 
• 124-38-9 carbon dioxide 
• 620-84-8 4-methyldiphenylamine 
• 121-69-7 N,N-dimethyl-aniline 
• 99-97-8 Dimethyl-p-toluidine 
• 74-88-4 methyl iodide 
• 108-90-7 chlorobenzene 
• 108-86-1 bromobenzene 
• 591-17-3 meta-bromotoluene 
• 591-50-4 iodobenzene 
• 625-95-6 3-Iodotoluene 
• 3899-96-5 4-methylphenyl tosylate 

Downstream Products

• 41018-61-5 N-phenyl-N-(p-tolyl)nitrous amide 
• 24075-48-7 3,9-dimethyl-9H-carbazole 
• 1359859-45-2 C₂₃H₂₉NO₄ 

Relevant articles and documents

Cu(I)–N-heterocyclic carbene-catalyzed base free C–N bond formation of arylboronic acids with amines and azoles

A new N-heterocyclic carbene (NHC) precursor of imidazolium chloride and its corresponding Cu(I)–NHC complex 1 was synthesized. The complex 1 was found to be a highly effective catalyst for Chan-Evans-Lam coupling of arylboronic acid with amines and azoles (including imidazole, pyrazole and triazole), without addition of base at room temperature. Various substituents on three substrates can be tolerated, giving the desired coupling products in good to excellent yields (62–94%). The method is practical and offers an alternative to the corresponding copper-catalyzed Chan-Evans-Lam process for the construction of C–N bonds.

Double Ligands Enabled Ruthenium Catalyzed ortho-C?H Arylation of Dialkyl Biarylphosphines: Straight and Economic Synthesis of Highly Steric and Electron-Rich Aryl-Substituted Buchwald-Type Phosphines

A double-ligands enabled ruthenium catalyzed C(sp2)?H arylation of dialkyl phosphines is described, which provides a straight access to aryl-substituted dialkyl phosphine ligands. The combination of 1,3-diketone and amino acid ligands is essential for this transformation. An important six-membered cycloruthenium intermediate was successfully isolated and characterized by X-ray diffraction. Mechanistic studies showed that the 1,3-diketone promoted the process of oxidative addition of cycloruthenium intermediate. Some of modified CyJohnPhos ligands exhibited highly catalytic activity in palladium catalyzed C?N bond formation. (Figure presented.).

Design of Benzimidazolyl Phosphines Bearing AlterableP,OorP,N-Coordination: Synthesis, Characterization, and Insights into Their Reactivity

A new series of hemilabile benzimidazolyl phosphines is reported. Entities in this ligand family can be easily assembled and prepared on a large scale via a simple one-pot procedure. X-ray crystallographic analyses show that the Pd metal center can coordinate in different fashions, where it relies on the size of the ?PR2group. With the same ligand scaffold, the ligand having a ?PCy2moiety displays better efficiency in expediting aromatic C-C bond-coupling reactions, while the ligand associated with a ?P-t-Bu2group, in contrast, promotes C-N bond-forming reactions.