628-81-9 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 628-81-9 differently. You can refer to the following data:
1. colourless liquid
2. Ethyl butyl ether is a colorless liquid
Uses
Different sources of media describe the Uses of 628-81-9 differently. You can refer to the following data:
1. Extraction solvent, inert reaction medium.
2. As an extraction solvent
Synthesis Reference(s)
The Journal of Organic Chemistry, 39, p. 3050, 1974 DOI: 10.1021/jo00934a027
General Description
A clear colorless liquid with an ethereal odor. Flash point 40°F. Less dense than water. Vapors heavier than air.
Air & Water Reactions
Highly flammable. Slightly soluble in water. Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979. p.151-154, 164]. A mixture of liquid air and diethyl ether exploded spontaneously [MCA Case History 616. 1960].
Reactivity Profile
Ethers, such as Butyl ethyl ether, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
Hazard
Flammable, dangerous fire risk.
Health Hazard
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Flammable
Safety Profile
Moderately toxic by
ingestion. A skin and eye irritant. A very
dangerous fire hazard when exposed to heat
or flame; can react vigorously with oxidizing
materials. Keep away from heat and open
flame. To fight fire, use alcohol foam, CO2,
dry chemical. When heated to
decomposition it emits acrid smoke and
irritating fumes. See also ETHERS.
Potential Exposure
Used as a solvent for extraction and in
making other chemicals
Shipping
UN1179 Ethyl butyl ether, Hazard Class: 3;
Labels: 3-Flammable liquid.
Purification Methods
Purify by drying with CaSO4, by passage through a column of activated alumina (to remove peroxides), followed by prolonged refluxing with Na and then fractional distillation. [Beilstein 4 IV 1518.]
Incompatibilities
May form explosive mixture with air.
Heat or prolonged storage may cause the formation of unstable peroxides. Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, and epoxides. Attacks some plastics,
rubber and coatings. May accumulate static electrical
charges, and may cause ignition of its vapors.
Check Digit Verification of cas no
The CAS Registry Mumber 628-81-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 628-81:
(5*6)+(4*2)+(3*8)+(2*8)+(1*1)=79
79 % 10 = 9
So 628-81-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H14O/c1-3-5-6-7-4-2/h3-6H2,1-2H3
628-81-9Relevant articles and documents
Dehydrogenative ester synthesis from enol ethers and water with a ruthenium complex catalyzing two reactions in synergy
Ben-David, Yehoshoa,Diskin-Posner, Yael,Kar, Sayan,Luo, Jie,Milstein, David,Rauch, Michael
supporting information, p. 1481 - 1487 (2022/03/07)
We report the dehydrogenative synthesis of esters from enol ethers using water as the formal oxidant, catalyzed by a newly developed ruthenium acridine-based PNP(Ph)-type complex. Mechanistic experiments and density functional theory (DFT) studies suggest that an inner-sphere stepwise coupled reaction pathway is operational instead of a more intuitive outer-sphere tandem hydration-dehydrogenation pathway.
The Guanidine-Promoted Direct Synthesis of Open-Chained Carbonates
Shang, Yuhan,Zheng, Mai,Zhang, Haibo,Zhou, Xiaohai
, p. 933 - 938 (2019/09/30)
In order to reduce CO2 accumulation in the atmosphere, chemical fixation methodologies were developed and proved to be promising. In general, CO2 was turned into cyclic carbonates by cycloaddition with epoxides. However, the cyclic carbonates need to be converted into open-chained carbonates by transesterification for industrial usage, which results in wasted energy and materials. Herein, we report a process catalyzed by tetramethylguanidine (TMG) to afford linear carbonates directly. This process is greener and shows potential for industrial applications.
Conversion of ethanol into linear primary alcohols on gold, nickel, and gold–nickel catalysts
Chistyakov,Zharova,Tsodikov,Nikolaev,Krotova,Ezzhelenko
, p. 803 - 811 (2016/12/07)
The direct conversion of ethanol into the linear primary alcohols CnH2n+1OH (n = 4, 6, and 8) in the presence of the original mono- and bimetallic catalysts Au/Al2O3, Ni/Al2O3, and Au–Ni/Al2O3 was studied. It was established that the rate and selectivity of the reaction performed under the conditions of a supercritical state of ethanol sharply increased in the presence of Au–Ni/Al2O3. The yield of target products on the bimetallic catalyst was higher by a factor of 2–3 than that reached on the monometallic analogs. Differences in the catalytic behaviors of the Au, Ni, and Au–Ni systems were discussed with consideration for their structure peculiarities and reaction mechanisms.
