38435-02-8

Upstream product

• 3282-30-2 pivaloyl chloride 
• 75-98-9 Trimethylacetic acid 
• 27943-35-7 2,2-dimethyl-3-(phenylthio)propionic acid 
• 170891-76-6 α,α,α-trimethyl-N-(quinolin-8-yl)acetamide 
• 38434-93-4 (2,2-Dichloro-3,3-dimethyl-cyclopropanesulfonyl)-benzene 
• 35347-56-9 1,1-Dichloro-2,2-dimethyl-3-phenylmercaptocyclopropan 
• 49639-05-6 1-(phenylsulfonyl)-2-methyl-2-propene 
• 882-33-7 diphenyldisulfane 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 51916-36-0 2-Phenylthiomethyl-2-methyl-1-propanol 
• 247146-53-8 3-benzenesulfonyl-2,2-dimethyl-propan-1-ol 
• 87279-54-7 2,2-dimethyl-3-(phenylsulfonyl)propanenitrile 
• 38434-95-6 (2,2-Diethoxy-3,3-dimethyl-cyclopropanesulfonyl)-benzene 

Downstream Products

• 380579-43-1 (4-benzenesulfonyl-3,3-dimethyl-2-oxo-butyl)-phosphonic acid dimethyl ester 
• 380579-24-8 6-(2-benzenesulfonyl-1,1-dimethyl-ethyl)-2-[2,3-bis-(tert-butyl-dimethyl-silanyloxy)-butyl]-3,4-dihydro-2H-pyran 
• 380579-82-8 (7S,9R,10R)-1-Benzenesulfonyl-9,10-bis-(tert-butyl-dimethyl-silanyloxy)-7-hydroxy-2,2-dimethyl-undecan-3-one 
• 380579-12-4 (2S,6S)-2-(2-Benzenesulfonyl-1,1-dimethyl-ethyl)-6-[(2R,3R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-butyl]-2-methoxy-dihydro-pyran-3-one 
• 380579-87-3 (2S,3S,6S)-2-(2-Benzenesulfonyl-1,1-dimethyl-ethyl)-6-[(2R,3R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-butyl]-2-methoxy-tetrahydro-pyran-3-ol 
• 1053654-32-2 (E)-(7S,9R,10R)-1-Benzenesulfonyl-9,10-bis-(tert-butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2,2-dimethyl-undec-4-en-3-one 
• 380579-77-1 (7S,9R,10R)-1-Benzenesulfonyl-9,10-bis-(tert-butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2,2-dimethyl-undecan-3-one 
• 380579-07-7 (2S,6S)-2-(2-Benzenesulfonyl-1,1-dimethyl-ethyl)-6-[(2R,3R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-butyl]-4-[2-(tert-butyl-diphenyl-silanyloxy)-eth-(E)-ylidene]-2-methoxy-dihydro-pyran-3-one 
• 380579-02-2 (2S,3S,6S)-2-(2-Benzenesulfonyl-1,1-dimethyl-ethyl)-6-[(2R,3R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-butyl]-4-[2-(tert-butyl-diphenyl-silanyloxy)-eth-(E)-ylidene]-2-methoxy-tetrahydro-pyran-3-ol 
• 380578-98-3 (2S,3S,6S)-2-(2-Benzenesulfonyl-1,1-dimethyl-ethyl)-6-[(2R,3R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-butyl]-4-[2-(tert-butyl-diphenyl-silanyloxy)-eth-(E)-ylidene]-2-methoxy-3-triethylsilanyloxy-tetrahydro-pyran 
• 38434-99-0 3-Benzenesulfonyl-2,2-dimethyl-propionic acid methyl ester 
• 38435-00-6 3-Benzenesulfonyl-2,2-dimethyl-propionic acid ethyl ester 

Relevant academic research and scientific papers

Nickel-catalyzed direct thiolation of C(sp3)-H bonds in aliphatic amides

Nickel-catalyzed thiolation of the inactivated methyl C(sp3)-H bonds of aliphatic amides with disulfide is described. It is a novel strategy for the synthesis of thioethers with the ultimate goal of generating thioether carboxylic acids with various functional groups.

A short synthetic pathway to a fully-functionalized southern hemisphere of the antitumor macrolide bryostatin 1.

[reaction--see text] An 18-step asymmetric synthesis of the bryostatin 1 "southern hemisphere" fragment (1) has been developed. Key steps include an aldol reaction between 6 and 7 and a dehydration to establish the (E)-exocyclic alkene in 2 and a stereose

RETROVIRAL PROTEASE INHIBITORS

Urea-containing hydroxyethylamine peptide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

α-Oxo Sulfones. 4. Correction of a Pretended α-Oxo Sulfone by an Unambiguous Synthesis of the Revised Structure

By an independent synthesis the oxidation product of 1,1-dichloro-2,2-dimethyl-1-(phenylthio)-3-butene (1) was shown not to be α-oxo sulfone "2" as published earlier but a phenylsulfonyl γ-butyrolactone, 3.This synthesis involves the intramolecular reaction of a sulfenic carboxylic mixed anhydride with an olefinic bond.A rationale for the formation of 3 from 1 is presented.