3852-11-7

Basic information

• Product Name: 3-METHOXYISOBUTYRIC ACID METHYL ESTER
• Synonyms: 3-METHOXYISOBUTYRIC ACID METHYL ESTER;3-METHOXY-2-METHYLPROPIONIC ACID METHYL ESTER;METHYL 3-METHOXY-2-METHYLPROPIONATE;METHYL 3-METHOXYISOBUTYRATE;Methoxyisobutyricacidmethylester;3-METHOXYISOBUTYRIC ACID METHYL ESTER (BETA-) 97+%;methyl 3-methoxy-2-methylpropanoate;methyl 3-methoxy-2-methyl-propanoate
• CAS NO: 3852-11-7
• Molecular Formula: C₆H₁₂O₃
• Molecular Weight: 132.16
• EINECS: 223-359-7
• Mol File: 3852-11-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 148°C
• Flash Point: 46°C(lit.)
• Appearance: /
• Density: 0,98 g/cm3
• Refractive Index: 1.4040-1.4060
• CAS DataBase Reference: 3-METHOXYISOBUTYRIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXYISOBUTYRIC ACID METHYL ESTER(3852-11-7)
• EPA Substance Registry System: 3-METHOXYISOBUTYRIC ACID METHYL ESTER(3852-11-7)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 3272
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 3852-11-7(Hazardous Substances Data)

Usage

General Description

3-Methoxyisobutyric acid methyl ester, also known as MIBA, is a chemical compound with the formula C6H12O3. It is a colorless liquid with a fruity odor and is commonly used as a flavoring agent in the food and beverage industry. MIBA is also used as a fragrance ingredient in cosmetics and personal care products. In addition, it has been identified as a potential biomarker for certain metabolic disorders and has been studied for its potential role in energy metabolism and lipid homeostasis. MIBA is considered to be of low toxicity, with no known adverse effects on human health at typical exposure levels.

Upstream product

• 67-56-1 methanol 
• 31413-67-9 β-methoxy-isobutyronitrile 
• 10500-24-0 3-methoxy-2-methyl propanoic acid 
• 80-62-6 methacrylic acid methyl ester 
• 123-63-7 paracetaldehyde 
• 186581-53-3 diazomethane 
• 13836-62-9 2-methoxy-2-methylpropanoic acid 
• 22421-97-2 methyl 2-chloroisobutyrate 
• 124-41-4 sodium methylate 
• 13141-08-7 β-methoxy-isobutyraldehyde 

Downstream Products

• 80-62-6 methacrylic acid methyl ester 
• 79-41-4 poly(methacrylic acid) 
• 86177-97-1 N,N-Dimethylaminoethyl 2-methyl-3-methoxypropionate 
• 10500-24-0 3-methoxy-2-methyl propanoic acid 

Relevant articles and documents

MANUFACTURING METHOD OF β-SUBSTITUTED PROPIONIC ACID AMIDE AND N-SUBSTITUTED (METH)ACRYLAMIDE

PROBLEM TO BE SOLVED: To provide a method for industrially manufacturing β-alkoxy propionic acid amide, β-amino propionic acid amide and N-substituted (meth)acryl amide using (meth)acrylic acid ester as starting material at high yield and high purity. SOLUTION: There is provided a method for obtaining N-substituted (meth)acryl amide represented by target compound formula (7) by conducting an amidation reaction with amine using β-substituted propionic acid ester represented by the formula (1) of a product of a Michael addition reaction of (meth)acrylic acid ester and alcohol or amine in presence of a metal complex as a catalyst to obtain β-substituted propionic acid amide represented by the formula (3) and conducting a thermal decomposition reaction of β-substituted propionic acid amide in presence of the metal complex as the catalyst to eliminate alcohol or amine. A-CH2-C(R1)H-C(=O)-OR2 (1), A-CH2-C(R1)H-C(=O)-N(R3)R4 (3), CH2=C(R1)-C(=O)-N(R3)R4 (7) SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

QUATERNARY SALTS OF N,N-DIMETHYLAMINOETHYL ESTERS OF PIVALIC AND 2-METHYL-3-METHOXYPROPIONIC ACID AND THEIR HYDROLYSIS

The synthesis and kinetics of quaternization of model compounds of poly(N,N-dimethylaminoethyl methacrylate) in water-alcoholic solutions brought about by methyl iodide and the alkaline hydrolysis of products in water have been investigated.N,N-Dimethylaminoethyl pivalate was selected as a model of the structural unit of the reported polymer; N,N-dimethylaminoethyl-2-methyl-3-methoxypropionate was the model of the terminal unit of the anionically prepared polymer.