38824-11-2

Basic information

• Product Name: Methanone, (2-aminophenyl)(3-methoxyphenyl)-
• CAS NO: 38824-11-2
• Molecular Formula: C14H13NO2
• Molecular Weight: 227.263
• Mol File: 38824-11-2.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Methanone, (2-aminophenyl)(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-aminophenyl)(3-methoxyphenyl)-(38824-11-2)
• EPA Substance Registry System: Methanone, (2-aminophenyl)(3-methoxyphenyl)-(38824-11-2)

Safety Data

• Hazardous Substances Data: 38824-11-2(Hazardous Substances Data)

Upstream product

• 19056-41-8 3-bromo-p-anisidine 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 
• 1885-29-6 anthranilic acid nitrile 
• 118-92-3 anthranilic acid 
• 38824-10-1 N-(2-(3-methoxybenzoyl)phenyl)acetamide 
• 591-31-1 3-methoxy-benzaldehyde 
• 19591-17-4 o-iodoacetanilide 
• 1527-89-5 3-methoxybenzonitrile 
• 62-53-3 aniline 
• 10365-98-7 3-methoxyphenylboronic acid 
• 118-48-9 isatoic anhydride 
• 2398-37-0 3-methoxyphenyl bromide 

Downstream Products

• 265329-05-3 2,2,2-trichloro-N-[2-(3-metoxybenzoyl)phenyl]acetamide 
• 1449373-65-2 3-[5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-(3-methoxyphenyl)quinolin-2(1H)-one 
• 1449374-09-7 4-{5-(4-chlorophenyl)-3-[4-(3-methoxyphenyl)-2-oxo-1,2-dihydroquinolin-3-yl]-4,5-dihydro-1H-pyrazol-1-yl}-4-oxobutanoic acid 
• 1449373-20-9 (E)-3-[3-(4-chlorophenyl)acryloyl]-4-(3-methoxyphenyl)quinolin-2(1H)-one 
• 1449372-84-2 3-acetyl-4-(3-methoxyphenyl)quinolin-2(1H)-one 
• 1322605-52-6 2-[1-(3-methoxyphenyl)ethenyl]benzenamine 

Relevant articles and documents

Asymmetric Synthesis of Hydroquinazolines Bearing C4-Tetrasubstituted Stereocenters via Kinetic Resolution of α-Tertiary Amines

A novel protocol for asymmetric synthesis of hydroquinazolines bearing C4-tetrasubstituted stereocenters has been achieved through kinetic resolution of 2-amido α-tertiary benzylamines via chiral phosphoric acid catalyzed intramolecular dehydrative cyclizations. This method gave access to both α-tertiary benzylamines and hydroquinazolines with broad scope and high enantioselectivities. An intriguing restricted rotation of the C-N bond was observed for hydroquinazoline products bearing C4-tetrasubstituted stereocenters.

Visible Light Induced Cyclization to Spirobi[indene] Skeletons from Functionalized Alkylidienecyclopropanes

In this paper, we revealed a metal-free and visible light photoinduced method for the rapid construction of spirobi[indene] skeletons, providing a simple and efficient way for easy access to spirobi[indene] scaffolds under mild conditions along with a broad substrate scope and good functional group tolerance.

Palladium Catalyzed Direct Acylation of Iodo-Acetanilides/Iodo-Phenyl Acetates: Domino One-Pot Synthesis of 2-Quinolinones

Pd-catalyzed direct acylation reaction of iodoacetanilides/iodophenyl acetates with aldehydes is presented. Simple, bench-top aldehydes were used as non-toxic acylating agents. This protocol comprises direct coupling with aldehydes without activating the carbonyl group and without directing group assistance. The strategy was applied to a domino one-pot synthesis of 2-quinolinones through acylation and intramolecular aldol condensation. Significantly, the strategy was extended to the domino one-pot synthesis of drugs and bioactive compounds.